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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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SYP / Synaptophysin Antibody (clone SY38) LS‑C11464
Synaptophysin antibody LS-C11464 is an unconjugated mouse monoclonal antibody to Synaptophysin (SYP) from human, mouse and rat. Validated for IHC and WB.
Antibody
Catalog
Size
Price
LS-C11464-25
25 µg (0.05 mg/ml)
$800

Popular SYP / Synaptophysin Products

IHC of paraffin-embedded Human pancreas tissue using anti-SYP mouse monoclonal antibody.
Species: Human
Applications: IHC, IHC - Paraffin, Immunofluorescence, Western blot
Antibody
Species: Rat, Mouse
Applications: IHC, Western blot
Anti-SYP mouse monoclonal antibody immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY SYP.
Species: Human, Dog
Applications: Immunofluorescence, Western blot
SYP Antibody immunohistochemistry of formalin-fixed and paraffin-embedded human brain tissue followed by peroxidase-conjugated secondary antibody and DAB staining.
Species: Human, Mouse
Applications: IHC, IHC - Paraffin, Immunofluorescence, Western blot, Flow Cytometry

Product Description

Synaptophysin antibody LS-C11464 is an unconjugated mouse monoclonal antibody to Synaptophysin (SYP) from human, mouse and rat. Validated for IHC and WB.

Specifications

Target
Human SYP / Synaptophysin
Synonyms
SYP, MRX, Synaptophysin, MRXSYP
Host
Mouse
Reactivity
Human, Mouse, Rat (tested or 100% immunogen sequence identity)
Clonality
IgG1 Monoclonal [SY38]
Conjugations
Unconjugated
Purification
Protein A purified
Modifications
Unmodified
Applications
  • IHC
  • IHC - Paraffin
  • IHC - Frozen
  • Western blot
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Immunogen
Synaptophysin presynaptic vesicles.
Specificity
Recognizes synaptophysin, also known as Major synaptic vesicle protein p38. Synaptophysin is a 313 amino acid ~38kD multi pass transmembrane glycoprotein containing a single domain. Synaptophysin is characteristic of small neurosecretory vesicles and is also present in neuroendocrine cells of neuronal and epithelial phenotype. Synaptophysin is widely used as a marker for nerve terminals and for differentiating neuroendocrine tumors. Has been used to detect synaptophysin in a number of neuronal and adrenal tumors including, pheochromocytomas, ganglioneuromas, neuroendocrine tumors of epithelial origin; pancreatic islet cell carcinoma, bronchial and gastrointestinal carcinoids and medullary carcinoma of the thyroid.
Presentation
PBS, 0.09% Sodium Azide, 0.5% BSA
Storage
Short term: -20°C; Long term: -20°C.
Restrictions
For research use only.
About SYP / Synaptophysin
Synaptophysin (Syn1) is an abundant synaptic vesicle membrane protein that contains four transmembrane regions. It forms a high molecular weight complex in the vesicle membrane containing at least four Syn I subunits and an 18 kD protein termed synaptobrevin/VAMP. Syn I is phosphorylated by both serine/threonine and tyrosine kinases on its cytoplasmic tail. Knockout studies in mice have shown that it is not essential for neurotransmitter release. P08247 X06389 CAA29686.1


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Requested From: United States
Date Requested: 10/19/2018

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