Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Human (tested or 100% immunogen sequence identity)
Tissue culture supernatant
IHC - Frozen
Specificity and Use
Synuclein antibody was raised against recombinant human alpha synuclein
Reacts with alpha Synuclein. By Western blot the antibody shows no reactivity with beta or gamma synuclein. This antibody was shown to stain Lewy bodies in frozen section of human brain with Parkinson's disease and glial inclusions in frozen section of human brain with Multiple System Atrophy
Western blotting on recombinant alpha synuclein: 1:2000-1:4000. Lane 1: Recombinant human alpha synuclein. Lane 2: Recombinant human beta synuclein. Lane 3: Recombinant human gamma synuclein. Immunohistochemistry (frozen sections): 1:250-1:500. Optimal wo
Tissue culture supernatant, 0.2 micron filtered
Store at -20°C. Aliquot to avoid freeze/thaw cycles. Store undiluted.