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Anti-Synuclein Alpha + Beta Antibody (Nitrated) LS-C76183


Wt. Vol. Conc. Price
100 µg - - $530
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)

Most Popular Synuclein Alpha + Beta Antibodies

Anti-Synuclein Alpha + Beta Antibody (Nitrated) LS-C26330
Mouse Monoclonal to Human Synuclein Alpha + Beta
IHC, ICC, Western blot
Anti-Synuclein Alpha + Beta Antibody (Tyr39) LS-C26331
Mouse Monoclonal to Human Synuclein Alpha + Beta
IHC, ICC, Western blot
Anti-Synuclein Alpha + Beta Antibody IHC-plus™ LS-B2330
Mouse Monoclonal (IgG2a) to Human Synuclein Alpha + Beta
Human, Mouse
IHC - Paraffin, Immunofluorescence, Western blot, Immunoprecipitation, ELISA
Immunohistochemistry Image

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Mouse Monoclonal (IgG) to Human Synuclein Alpha + Beta
IHC, Western blot, ELISA


Human Synuclein Alpha + Beta
Human (tested or 100% immunogen sequence identity)
IgG Monoclonal
Protein A purified


  • IHC
  • Western blot (1 - 3 µg/ml)
  • ELISA (0.1 - 1 µg/ml)

Specificity and Use

Recombinant full-length oxidized human a-Synuclein, which shares 95% amino acid sequence homology with mouse and rat a-Synucleins.
Reacts with the C-terminal region1 of the nitrated/oxidized form of human a-Synuclein, as well as with mutated b-Synuclein.1 The binding of nSyn 12 is dependent upon nitration of either Tyr125 or Tyr136, with the recognition of Tyr136 dominating that of Tyr125.1 On Western blots, it identifies the target band at ~18kD. Reactivity has been confirmed with WT ONOO-, a recombinant wild-type form of a-Synuclein nitrated at Tyr39, 125, 133, and 136 by peroxynitrate, and with human brain extracts by Western blotting. Reactivity has also been confirmed with human DLB (dementia with Lewy bodies) and MSA (multiple system atrophy) brains by immunohistochemistry.1 Cross-reactivity with b-synuclein has been observed using bacterially-expressed and purified recombinant human proteins.1.
Suitable for use in ELISA, Western Blot, Immunohistochemistry. ELISA: 0.1-1.0 ug/ml. Western Blot: 1-3 ug/ml. Immunohistochemistry1:1-5 ug.


PBS, pH 7.4, 0.1% sodium azide.
For research use only.

About Synuclein Alpha + Beta

Requested From: United States
Date Requested: 10/25/2016

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