Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Mouse Monoclonal [clone 3D10] (IgG1) to Human SUZ12
IHC, IHC - Paraffin, Western blot, ELISA
Mouse Monoclonal (IgG1) to Human SUZ12
ICC, Western blot, ELISA
Human (tested or 100% immunogen sequence identity)
Protein G purified
ICC (10 µg/ml)
Western blot (1 - 2 µg/ml)
ELISA (0.5 - 1 µg/ml)
Specificity and Use
SUZ12 antibody was raised against e. coli-derived rhSUZ12. (aa 131 - 305).
Recognizes human SUZ12.
Suitable for use in Direct ELISA, Western Blot, and Immunocytochemistry. Direct ELISA: 0.5-1.0 ug/ml detection limit for rhSUZ12 is ~5 ng/well. Western Blot: 1-2 ug/ml detection limit for rhSUZ12 is ~25 ng/lane under non-reducing and reducing conditions. Immunocytochemistry: 10 ug/ml.
Lyophilized from PBS, 5% trehalose. Reconstitute, 200 ul sterile 40-50% glycerol, PBS.
SUZ12 Antibody, ChET 9 protein Antibody, Joined to JAZF1 protein Antibody, CHET9 Antibody, JJAZ1 Antibody, KIAA0160 Antibody, Polycomb protein SUZ12 Antibody
Polycomb group (PcG) protein. Component of the PRC2/EED-EZH2 complex, which methylates 'Lys-9' (H3K9me) and 'Lys-27' (H3K27me) of histone H3, leading to transcriptional repression of the affected target gene. The PRC2/EED-EZH2 complex may also serve as a recruiting platform for DNA methyltransferases, thereby linking two epigenetic repression systems. Genes repressed by the PRC2/EED-EZH2 complex include HOXC8, HOXA9, MYT1 and CDKN2A.