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Anti-STXBP2 Antibody (aa58-70) IHC-plus™ LS-B2356

Note: This antibody replaces LS-C25383


Wt. Vol. Conc. Price
50 µg - 1 mg/ml Unavailable

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Anti-STXBP2 Antibody (aa58-70) IHC-plus™ LS-B2356
Rabbit Polyclonal to Human STXBP2
Human, Monkey, Mouse, Rat, Bovine, Dog, Hamster, Horse, Pig, Xenopus
IHC - Paraffin, Western blot, Immunoprecipitation
Immunohistochemistry Image
Anti-STXBP2 Antibody (aa440-469) LS-C161598
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Anti-STXBP2 Antibody IHC-plus™ LS-B13261
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Human, Mouse, Rat, Guinea pig, Horse, Rabbit, Cow
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Anti-STXBP2 Antibody LS-C404383
Rabbit Polyclonal (IgG) to Human STXBP2
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Anti-STXBP2 Antibody IHC-plus™ LS-B14591
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100% Guaranteed 100% Guaranteed
Rabbit Polyclonal to Human STXBP2
Human, Monkey, Mouse, Rat, Bovine, Dog, Hamster, Horse, Pig, Xenopus
IHC - Paraffin, Western blot, Immunoprecipitation


Human STXBP2
Human, Monkey, Mouse, Rat, Bovine, Dog, Hamster, Horse, Pig, Xenopus (tested or 100% immunogen sequence identity)
Rabbit, Chicken, Zebrafish (at least 90% immunogen sequence identity)
Immunoaffinity purified


  • IHC - Paraffin (2.5 µg/ml)
  • Western blot
  • Immunoprecipitation

Specificity and Use

STXBP2 antibody was raised against synthetic peptide corresponding to aa 58-70 (V58EDINKRREPIPS70) of human Munc-18. Percent identity by BLAST analysis: Human, Gorilla, Orangutan, Gibbon, Monkey, Marmoset, Mouse, Rat, Hamster, Elephant, Panda, Bovine, Dog, Horse, Pig, Opossum, Platypus, Xenopus (100%); Rabbit, Turkey, Chicken, Salmon, Stickleback, Pufferfish, Zebrafish, Eye worm, Nematode (92%); Lizard (85%).
Recognizes human Munc at ~67kD by Western Blot. Species cross-reactivity: mouse and rat.
Immunohistochemistry: LS-B2356 was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for LS-B2356 was determined to be 2.5 ug/ml.


PBS, 1 mg/ml BSA, 0.05% sodium azide.
+4°C or -20°C, Avoid repeated freezing and thawing.
For research use only.

About STXBP2

Q15833 NM_006949 NP_008880.2

STXBP2 Antibody, Hunc18b Antibody, MUNC18-2 Antibody, Protein unc-18 homolog B Antibody, UNC18B Antibody, Pp10122 Antibody, Syntaxin binding protein 2 Antibody, Syntaxin-binding protein 2 Antibody, Protein unc-18 homolog 2 Antibody, Unc-18B Antibody, UNC18-2 Antibody

Involved in intracellular vesicle trafficking and vesicle fusion with membranes. Contributes to the granule exocytosis machinery through interaction with soluble N-ethylmaleimide-sensitive factor attachment protein receptor (SNARE) proteins that regulate membrane fusion. Regulates cytotoxic granule exocytosis in natural killer (NK) cells.


Anti-STXBP2 antibody IHC of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B2356 concentration 5 ug/ml.

Western blot

Western blot
Western blot analysis for Munc18 in 750 ug rat brain homogenate immunoprecipitated with 1 ug, 5 ug, and 10 ug of (lanes 2-4) of LS-B2356 (lane 1: extract only).

Requested From: 
Date Requested: 4/24/2017

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