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Anti-STXBP1 / MUNC18-1 Antibody (phospho-Ser515) LS-C61872

Ordering

Wt. Vol. Conc. Price
- 100 µl - $355
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)
206-374-1102
866-206-6909
Orders@LSBio.com
 

Most Popular STXBP1 / MUNC18-1 Antibodies

Anti-STXBP1 / MUNC18-1 Antibody (clone 6D1) IHC-plus™ LS-B5542
Mouse Monoclonal [clone 6D1] (IgG2a,k) to Human STXBP1 / MUNC18-1
Human, Mouse
IHC - Paraffin, Western blot, ELISA
Unconjugated
Immunohistochemistry Image
Anti-STXBP1 / MUNC18-1 Antibody (phospho-Thr574) LS-C153567
Rabbit Polyclonal to Human STXBP1 / MUNC18-1
Human, Mouse, Rat
Immunofluorescence, Western blot, ELISA
Unconjugated
Anti-STXBP1 / MUNC18-1 Antibody (Internal) LS-C368532
Rabbit Polyclonal to Human STXBP1 / MUNC18-1
Human, Mouse, Rat, Bovine
IHC - Paraffin, ICC, Immunofluorescence, Western blot
Unconjugated
Immunohistochemistry Image

100% Guaranteed 100% Guaranteed
Rabbit Polyclonal to Rat STXBP1 / MUNC18-1
Rat, Human, Mouse, Bovine, Dog, Chicken, Xenopus
Western blot
Unconjugated

Details

Rat STXBP1 / MUNC18-1
Rabbit
Rat, Human, Mouse, Bovine, Dog, Chicken, Xenopus (tested or 100% immunogen sequence identity)
Polyclonal
Unconjugated
Immunoaffinity purified
Unmodified

Applications

Western blot (1:1000)

Specificity and Use

STXBP1 / MUNC18-1 antibody was raised against phosphopeptide corresponding to amino acid residues surrounding the phosphoSer515 of Munc-18.
pSer515
Specific for the ~65k Munc-18 protein phosphorylated at Ser515. Immunolabeling is blocked by the phosphopeptide used as antigen but not by the corresponding dephosphopeptide

Packaging

50 uL of 10 mM HEPES, pH 7.5, 150 mM sodium chloride, 0.1 mg/mL BSA, 50% glycerol.
Long term: -20°C; Short term: -20°C
For research use only.

About STXBP1 / MUNC18-1

P61764 NM_003165 NP_003156.1

STXBP1 Antibody, EIEE4 Antibody, HUNC18 Antibody, MUNC18-1 Antibody, N-Sec1 Antibody, NSEC1 Antibody, Protein unc-18 homolog 1 Antibody, Protein unc-18 homolog A Antibody, UNC18 Antibody, Unc18-1 Antibody, p67 Antibody, RBSEC1 Antibody, Unc-18A Antibody, Munc18 Antibody, Neuronal SEC1 Antibody, Syntaxin binding protein 1 Antibody, Syntaxin-binding protein 1 Antibody, UNC18A Antibody

May participate in the regulation of synaptic vesicle docking and fusion, possibly through interaction with GTP-binding proteins. Essential for neurotransmission and binds syntaxin, a component of the synaptic vesicle fusion machinery probably in a 1:1 ratio. Can interact with syntaxins 1, 2, and 3 but not syntaxin 4. May play a role in determining the specificity of intracellular fusion reactions.

Western blot

Western blot
Western blot of rat cortex lysate showing specific immunolabeling of the ~65k Munc-18 protein phosphorylated at Ser515. Immunolabeling is blocked by the phosphopeptide (peptide) used as antigen but not by the corresponding dephosphopeptide (not shown).
 

Requested From: United States
Date Requested: 12/5/2016

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