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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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STXBP1 / MUNC18‑1 Antibody (aa504‑553) LS‑C102845
Antibody
MUNC18-1 antibody LS-C102845 is an unconjugated rabbit polyclonal antibody to MUNC18-1 (STXBP1) from human, mouse, rat and other species. Validated for WB.
Catalog
Size
Price
LS-C102845-50
50 µg
Unavailable

Popular STXBP1 / MUNC18-1 Products

Antibody
Species: Human, Mouse, Rat
Applications: IHC, Western blot
Anti-STXBP1 antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B4446 concentration 5 ug/ml.
Species: Human, Monkey, Mouse, Rat, Bat, Bovine, Dog, Hamster, Rabbit
Applications: IHC, IHC - Paraffin, Western blot, Peptide Enzyme-Linked Immunosorbent Assay
Anti-STXBP1 antibody IHC of human brain, neuropil. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B5542 concentration 5 ug/ml.
Species: Human, Mouse
Applications: IHC, IHC - Paraffin, Western blot, ELISA
Antibody
Species: Human, Mouse, Rat
Applications: Immunofluorescence, Western blot, ELISA
Antibody
Species: Human, Monkey, Mouse, Rat
Applications: Western blot, ELISA

Product Description

MUNC18-1 antibody LS-C102845 is an unconjugated rabbit polyclonal antibody to MUNC18-1 (STXBP1) from human, mouse, rat and other species. Validated for WB.
About STXBP1 / MUNC18-1
May participate in the regulation of synaptic vesicle docking and fusion, possibly through interaction with GTP-binding proteins. Essential for neurotransmission and binds syntaxin, a component of the synaptic vesicle fusion machinery probably in a 1:1 ratio. Can interact with syntaxins 1, 2, and 3 but not syntaxin 4. May play a role in determining the specificity of intracellular fusion reactions. P61764 NM_003165 NP_003156.1

STXBP1 Antibody, EIEE4 Antibody, HUNC18 Antibody, MUNC18-1 Antibody, N-Sec1 Antibody, NSEC1 Antibody, Protein unc-18 homolog 1 Antibody, Protein unc-18 homolog A Antibody, UNC18 Antibody, Unc18-1 Antibody, p67 Antibody, RBSEC1 Antibody, Unc-18A Antibody, Munc18 Antibody, Neuronal SEC1 Antibody, Syntaxin binding protein 1 Antibody, Syntaxin-binding protein 1 Antibody, UNC18A Antibody


Specifications

Target
Human STXBP1 / MUNC18-1
Host
Rabbit
Reactivity
Human, Monkey, Mouse, Rat, Bat, Bovine, Dog, Guinea pig, Horse, Pig, Rabbit, Chicken, Xenopus, Zebrafish (tested or 100% immunogen sequence identity)
Clonality
IgG Polyclonal
Conjugations
Unconjugated. Also available conjugated with Biotin, FITC, HRP.
Purification
Immunoaffinity purified
Modifications
Unmodified
Applications
  • Western blot (0.2 - 1 µg/ml)
  • (applications tested for the base form of this product only)
Failed Applications
  • IHC - Paraffin
Immunogen
Synthetic peptide located between aa504-553 of human STXBP1 (P61764, NP_001027392). Percent identity by BLAST analysis: Human, Chimpanzee, Gorilla, Orangutan, Monkey, Marmoset, Mouse, Rat, Elephant, Dog, Bovine, Bat, Rabbit, Horse, Pig, Opossum, Guinea pig, Zebra finch, Chicken, Platypus, Xenopus (100%); Gibbon (93%); Zebrafish (86%).
Blocking Peptide
LS-E10722 - Lyophilized - 100 µg - $145.00
Immunizing peptide used to generate LS-C102845. Useful for pre-absorption and neutralization of the antibody's antigen binding site.
Epitope
aa504-553
Specificity
Human STXBP1
Usage
Western Blot: Suggested dilution at 1µg/ml in 5% skim milk / PBS buffer, and HRP conjugated anti-Rabbit IgG should be diluted in 1: 50,000 - 100,000 as second antibody. ELISA titer in peptide based assay: 1:12500.
Presentation
Lyophilized from PBS with 2% sucrose
Reconstitution
Distilled water
Storage
Long term: -20°C, the use of 50% glycerol is recommended if storing aliquots in -20°C for long term use (up to 1 year); Short term (less than 1 week): 4°C. Avoid freeze-thaw cycles.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Requested From: 
Date Requested: 6/21/2018

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