Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
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Technical.Support@LSBio.com - To request technical information requests about an LSBio product
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Sales@LSBio.com - To request information about fee-for-service contract IHC studies, IHC reports, distribution
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Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.
Human (tested or 100% immunogen sequence identity)
Mouse, Chicken (at least 90% immunogen sequence identity)
Polyclonal
Unconjugated
Protein A purified
Unmodified
Applications
Western blot (1:1000)
Flow Cytometry (1:10 - 1:50)
Specificity and Use
LS-E1469 - Lyophilized - 100 µg - $145.00
Immunizing peptide used to generate LS-C161582. Useful for pre-absorption and neutralization of the antibody's antigen binding site.
aa236-263
This STUB1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 236-263 amino acids from the C-terminal region of human STUB1.
Packaging
PBS, 0.09% sodium azide
Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
E3 ubiquitin-protein ligase which targets misfolded chaperone substrates towards proteasomal degradation. Collaborates with ATXN3 in the degradation of misfolded chaperone substrates: ATXN3 restricting the length of ubiquitin chain attached to STUB1/CHIP substrates and preventing further chain extension. Ubiquitinates NOS1 in concert with Hsp70 and Hsp40. Modulates the activity of several chaperone complexes, including Hsp70, Hsc70 and Hsp90.
STUB1 Antibody western blot of 293 cell line lysates (35 ug/lane). The STUB1 antibody detected the STUB1 protein (arrow).
Flow Cytometry
STUB1 Antibody flow cytometry of K562 cells (right histogram) compared to a negative control cell (left histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.