STAT5B

signal transducer and activator of transcription 5B

STAT5B is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein mediates the signal transduction triggered by various cell ligands, such as IL2, IL4, CSF1, and different growth hormones. It has been shown to be involved in diverse biological processes, such as TCR signaling, apoptosis, adult mammary gland development, and sexual dimorphism of liver gene expression. This gene was found to fuse to retinoic acid receptor-alpha (RARA) gene in a small subset of acute promyelocytic leukemias (APLL). The dysregulation of the signaling pathways mediated by this protein may be the cause of the APLL.

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Products

Antibodies (94)

ELISA Kits (14)

Proteins (8)

Type

Cell-Based (1)

Cell-Based Phosphorylation (3)

Custom (4)

DNA Binding (1)

DNA Binding Phosphorylation (1)

Over-Expression Lysate (2)

Primary (94)

Recombinant (6)

Sandwich (4)

Target

STAT5B (116)

Reactivity

Human (98)

Mouse (55)

Rat (51)

Bovine (5)

Chicken (3)

Chimpanzee (6)

Dog (13)

Gibbon (9)

Guinea pig (6)

Hamster (1)

Horse (8)

Monkey (1)

Pig (15)

Rabbit (10)

Sheep (4)

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Application

IHC (37)

IHC-P (19)

WB (89)

ChrIP (1)

ELISA (37)

GS (1)

ICC (3)

IF (11)

IP (24)

Peptide-ELISA (4)

Host

rabbit (75)

mouse (19)

Product Group

IHCPlus (5)

Isotype

IgG (56)

IgG1 (4)

IgG1,k (8)

IgG2a,l (6)

IgG2b (1)

Clonality

monoclonal mc (19)

polyclonal pc (74)

recombinant monoclonal rmc (1)

Clone

2D1 (1)

5B3 (2)

5D6 (1)

Format

12 x 8-Well Microstrips (2)

96-Well Microplate (4)

96-Well Strip Plate (8)

APC (1)

APC Conjugated (6)

Azide-free (1)

Biotin Conjugated (12)

Cy3 Conjugated (1)

Cy7 Conjugated (1)

FITC Conjugated (12)

HRP Conjugated (12)

PE Conjugated (6)

Unconjugated (44)

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Epitope

C-Terminus (10)

aa497-749 (8)

aa760-787 (7)

N-Terminus (5)

aa180-229 (4)

aa410-459 (4)

pSer731 (4)

aa40-280 (1)

aa675-703 (1)

aa697-746 (1)

aa737-787 (1)

aa767-787 (1)

aa774-787 (1)

aa777-787 (1)

p731 (1)

pSer133 (1)

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Publications

No (116)

Sample Type

Adherent Cell Cultures (4)

Cell Lysates (2)

Cell Supernatant (1)

Nuclear Lysates (2)

Plasma (3)

Serum (3)

Tissue Homogenates (1)

Tag

6His, C-terminus (2)

GST (1)

GST, N-terminus (1)

His-T7 (1)

Myc-DDK (Flag) (3)

Species

Human (7)

Source

293T Cells (1)

E. coli (3)

HEK 293 Cells (2)

Wheat Germ Extract (2)

Purification

Purified (1)

Low Endotoxin Level

Low endotoxin level (2)

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IHC-plus™ STAT5B Antibody (clone 5D6) LS-B5540

(4.0) Rating

Antibody:

STAT5B Mouse anti-Human Monoclonal (5D6) Antibody

Reactivity:

Human

Applications:

ELISA, IF, IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µg/$460

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IHC-plus™ STAT5B Antibody (N-Terminus) LS-B1679

(4.0) Rating

Antibody:

STAT5B Rabbit anti-Human Polyclonal (N-Terminus) Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µl/$460

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IHC-plus™ STAT5B Antibody (clone 2D1) LS-B5541

(4.0) Rating

Antibody:

STAT5B Mouse anti-Human Monoclonal (2D1) Antibody

Reactivity:

Human

Applications:

ELISA, IF, IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µg/$460

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STAT5B Antibody (aa40-280) LS-C376711

Antibody:

STAT5B Rabbit anti-Human Polyclonal (aa40-280) Antibody

Reactivity:

Human

Applications:

ChrIP, ELISA, IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µl/$294; 100 µl/$360

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Human STAT5B (Sandwich ELISA) ELISA Kit - LS-F35257

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.78 - 50 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Tissue Homogenates

Price:

1 Plate/$579

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Mouse/Human/Rat STAT5B (DNA-Binding ELISA) ELISA Kit - LS-F820

Type:

DNA Binding

Format:

12 x 8-Well Microstrips

Reactivity:

Mouse, Human, Rat

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Lysates, Nuclear Lysates

Price:

1 Plate/$694

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STAT5B Antibody (N-Terminus) LS-B4002

Antibody:

STAT5B Rabbit anti-Human Polyclonal (N-Terminus) Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

100 µl/$485

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STAT5B Antibody (N-Terminus, HRP) LS-C437902

Antibody:

STAT5B Rabbit anti-Human Polyclonal (N-Terminus) (HRP) Antibody

Reactivity:

Chicken, Rabbit, Mouse, Dog, Rat, Pig, Horse, Gibbon, Human

Applications:

IHC, IHC-P, WB

Format:

HRP Conjugated

Price:

100 µl/$469

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STAT5B Antibody (N-Terminus, Biotin) LS-C437900

Antibody:

STAT5B Rabbit anti-Human Polyclonal (N-Terminus) (Biotin) Antibody

Reactivity:

Chicken, Rabbit, Mouse, Dog, Rat, Pig, Horse, Gibbon, Human

Applications:

IHC, IHC-P, WB

Format:

Biotin Conjugated

Price:

100 µl/$469

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STAT5B Antibody (N-Terminus, FITC) LS-C437901

Antibody:

STAT5B Rabbit anti-Human Polyclonal (N-Terminus) (FITC) Antibody

Reactivity:

Chicken, Rabbit, Mouse, Dog, Rat, Pig, Horse, Gibbon, Human

Applications:

IHC, IHC-P, WB

Format:

FITC Conjugated

Price:

100 µl/$469

• Unconjugated
• HRP
• Biotin
• FITC

• Unconjugated
• HRP
• Biotin
• More...
  • FITC

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STAT5B Antibody LS-C499870

Antibody:

STAT5B Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, IF, IHC, WB

Format:

Unconjugated

Price:

50 µg/$294; 100 µg/$360

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STAT5B Antibody LS-C482236

Antibody:

STAT5B Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ICC, IF, IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µl/$286; 100 µl/$321; 200 µl/$386

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STAT5B Antibody LS-C753980

Antibody:

STAT5B Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IF, IHC, IP, WB

Format:

Unconjugated

Price:

100 µg/$341

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STAT5B Antibody LS-C753977

Antibody:

STAT5B Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IF, IHC, IP, WB

Format:

Unconjugated

Price:

100 µg/$351

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STAT5B Antibody (aa180-229) LS-B4572

Antibody:

STAT5B Rabbit anti-Human Polyclonal (aa180-229) Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

100 µl/$485

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STAT5B Antibody LS-C330891

Antibody:

STAT5B Rabbit anti-Human Polyclonal Antibody

Reactivity:

Rat, Human

Applications:

IF, IHC, WB

Format:

Unconjugated

Price:

20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503

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STAT5B Antibody (C-Terminus) LS-C10425

Antibody:

STAT5B Rabbit anti-Mouse Polyclonal (C-Terminus) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, GS, IP, WB

Format:

Unconjugated

Price:

100 µg/$913

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STAT5B Antibody LS-C836194

Antibody:

STAT5B Rabbit Recombinant Monoclonal Antibody

Applications:

ICC, IHC, IP, WB

Format:

Unconjugated

Price:

10 µl/$299; 100 µl/$548

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STAT5B Antibody (aa697-746) LS-C117581

Antibody:

STAT5B Rabbit anti-Human Polyclonal (aa697-746) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC, IHC-P, Peptide-ELISA, WB

Format:

Unconjugated

Price:

50 µl/$334; 100 µl/$397

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STAT5B Antibody (phospho-Ser731) LS-C199615

Antibody:

STAT5B Rabbit anti-Human Polyclonal (pSer731) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC, IHC-P, Peptide-ELISA, WB

Format:

Unconjugated

Price:

50 µl/$334; 100 µl/$397

Select

STAT5B Antibody (aa497-749) LS-C372804

Antibody:

STAT5B Rabbit anti-Human Polyclonal (aa497-749) Antibody

Reactivity:

Human

Applications:

ICC, IP, WB

Format:

Unconjugated

Price:

100 µl/$303; 200 µl/$343; 500 µl/$476; 1 ml/$543; 2 ml/$715; 5 ml/$1,182

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STAT5B Antibody (aa767-787) LS-C312984

Antibody:

STAT5B Rabbit anti-Human Polyclonal (aa767-787) Antibody

Reactivity:

Rabbit, Mouse, Sheep, Bovine, Rat, Pig, Horse, Human, Monkey

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

10 µg/$318; 100 µg/$470

Select

STAT5B Antibody (aa760-787) LS-C330677

Antibody:

STAT5B Rabbit anti-Human Polyclonal (aa760-787) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

200 µl/$734

Select

STAT5B Antibody (phospho-Ser731) LS-C808527

Antibody:

STAT5B Rabbit anti-Human Polyclonal (pSer731) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC, Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µl/$379; 200 µl/$421

Select

STAT5B Antibody (C-Terminus) LS-C10426

Antibody:

STAT5B Mouse anti-Mouse Monoclonal (C-Terminus) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, IP, WB

Format:

Unconjugated

Price:

100 µg/$842

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