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STAT5A

signal transducer and activator of transcription 5A

STAT5A is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is activated by, and mediates the responses of many cell ligands, such as IL2, IL3, IL7 GM-CSF, erythropoietin, thrombopoietin, and different growth hormones. Activation of this protein in myeloma and lymphoma associated with a TEL/JAK2 gene fusion is independent of cell stimulus and has been shown to be essential for tumorigenesis. The mouse counterpart of this gene is found to induce the expression of BCL2L1/BCL-X(L), which suggests the antiapoptotic function of this gene in cells. Alternatively spliced transcript variants have been found for this gene.

Gene Name: signal transducer and activator of transcription 5A
Synonyms: STAT5A, MGF, STAT5
Target Sequences: NM_003152 NP_003143.2 P42229

Publications (1)

1
Hyperactivated STAT3 in ALK-positive diffuse large B-cell lymphoma with clathrin-ALK fusion. Momose S, Tamaru J, Kishi H, Mikata I, Mori M, Toyozumi Y, Itoyama S. Human pathology. 2009 40:75-82. (ICC) [PubMed:18755494]

☰ Filters
Antibodies (135)
ELISA Kits (18)
Proteins (7)
Cell-Based (1)
Cell-Based Phosphorylation (2)
Competitive EIA (1)
Custom (3)
DNA Binding (1)
DNA Binding Phosphorylation (1)
Over-Expression Lysate (2)
Primary (135)
Recombinant (5)
Sandwich (9)
STAT5A (160)
Human (133)
Mouse (59)
Rat (58)
Bovine (3)
Chicken (2)
Chimpanzee (3)
Dog (5)
Horse (2)
Monkey (9)
Pig (12)
Porcine (1)
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Sheep (2)
Xenopus (1)
Zebrafish (1)
IHC (70)
IHC-P (17)
WB (130)
Flo (25)
DB (9)
ELISA (43)
GS (7)
ICC (7)
IF (30)
IP (16)
Peptide-ELISA (14)
rabbit (98)
mouse (35)
goat (2)
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monoclonal mc (35)
polyclonal pc (99)
recombinant monoclonal rmc (1)
4.00E+07 (1)
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pTyr694 (17)
aa586-688 (8)
aa673-773 (8)
pSer780 (8)
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aa722-771 (4)
640-720 aa (2)
720-800 aa (2)
Asym-Me2-Arg31 (2)
C-Terminus (2)
Me-Arg31 (2)
aa774-794 (2)
Amino Acid: 583-794 (1)
Internal (1)
Trp287 (1)
Tyr694 (1)
aa2-104 (1)
aa371-420 (1)
aa386-435 (1)
aa562-774 (1)
aa666-715 (1)
aa681-692 (1)
aa696-745 (1)
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aa744-794 (1)
aa745-794 (1)
aa763-797 (1)
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Purified (1)
STAT5A Antibody - Anti-STAT5A antibody IHC staining of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
Select
STAT5A Mouse anti-Human Monoclonal (9F7) Antibody
Dog, Rat, Human, Monkey
Flo, IF, IHC, IHC-P, WB
Unconjugated
50 µl/$460
Select
STAT5A Mouse anti-Human Monoclonal (aa774-794) (CF) Antibody
Human
Flo
CF Conjugated
100 Tests/$711
STAT5A Antibody - Anti-STAT5A antibody IHC staining of human breast. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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STAT5A Mouse anti-Human Monoclonal (4E7) Antibody
Human
Flo, IF, IHC, IHC-P, WB
Unconjugated
100 µl/$485
STAT5A Antibody - Anti-Stat5 pY694 Monoclonal Antibody - Immunohistochemistry. Immunohistochemistry using Anti-Stat5 pY694 monoclonal antibody shows detection of phosphorylated Stat5pY694 in human breast tissue (40X). The antibody was used a dilution to 20 ug/mL. The image shows breast epithelium with moderate nuclear staining. Tissue was formalin fixed and paraffin embedded. Antigen retrieval: steam sections in 0.1 M sodium citrate buffer, pH 6, for 20 min. The image shows the localization of antibody as the precipitated red signal, with a hematoxylin purple nuclear counterstain. Personal communication, Andrew Elston, Lifespan Biosciences, Seattle, WA.
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STAT5A Mouse anti-Mouse Monoclonal (pTyr694) (5F6.F1) Antibody
Mouse, Rat, Human
ELISA, IF, IHC, WB
Unconjugated
100 µg/$574
STAT5A ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
0.625 - 40 ng/ml
Colorimetric - 450nm (TMB)
Tissue Homogenates
1 Plate/$579
STAT5A ELISA Kit
Select
Sandwich
12 x 8-Well Microstrips
Mouse
31.25 - 2000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$651
STAT5A Antibody - STAT5 alpha Antibody in Immunohistochemistry (IHC)
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STAT5A Mouse anti-Human Monoclonal (Amino Acid: 583-794) (6D4) Antibody
Human
Flo, ICC, IF, IHC, WB
Unconjugated
100 µg/$503
STAT5A Antibody - IHC of paraffin-embedded ovarian cancer tissues using STAT5A mouse monoclonal antibody with DAB staining.
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STAT5A Mouse anti-Human Monoclonal (6D4) Antibody
Human
ELISA, Flo, IF, IHC, WB
Unconjugated
100 µl/$459
STAT5A Antibody - IHC of paraffin-embedded Human lymph node tissue using anti-STAT5A mouse monoclonal antibody.
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STAT5A Mouse anti-Human Monoclonal (OTI6D6) Antibody
Human
Flo, IF, IHC, IHC-P, WB
Unconjugated
100 µl/$434
STAT5A Antibody - IHC of paraffin-embedded Human lymph node tissue using anti-STAT5A mouse monoclonal antibody.
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STAT5A Mouse anti-Human Monoclonal (Carrier-free) (OTI6D6) Antibody
Human
Flo, IF, IHC, WB
Unconjugated, Carrier-free
100 µg/$511
STAT5A Antibody - IHC of paraffin-embedded Human lymph node tissue using anti-STAT5A mouse monoclonal antibody.
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STAT5A Mouse anti-Human Monoclonal (OTI9A5) Antibody
Human
Flo, IF, IHC, IHC-P, WB
Unconjugated
100 µl/$434
STAT5A Antibody - IHC of paraffin-embedded Human lymph node tissue using anti-STAT5A mouse monoclonal antibody.
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STAT5A Mouse anti-Human Monoclonal (Carrier-free) (OTI9A5) Antibody
Human
Flo, IF, IHC, WB
Unconjugated, Carrier-free
100 µg/$511
STAT5A Antibody - Anti-STAT5A antibody IHC staining of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
Select
STAT5A Mouse anti-Human Monoclonal (Carrier-free) (9F7) Antibody
Dog, Rat, Human, Monkey
Flo, IF, IHC, WB
Unconjugated, Carrier-free
100 µg/$511
STAT5A Antibody - Anti-STAT5A antibody IHC staining of human breast. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Select
STAT5A Mouse anti-Human Monoclonal (Carrier-free) (4.00E+07) Antibody
Dog, Rat, Human, Monkey
Flo, IF, IHC, WB
Unconjugated, Carrier-free
100 µg/$511
STAT5A Antibody - Immunohistochemistry using Anti-STAT5 pY694 monoclonal antibody shows detection of phosphorylated STAT5 pY694 in human breast tissue (40X). The antibody was used a dilution to 20 µg/mL. The image shows breast epithelium with moderate nuclear staining. Tissue was formalin fixed and paraffin embedded. No pre-treatment of sample was required. The image shows the localization of antibody as the precipitated red signal, with a hematoxylin purple nuclear counterstain.
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STAT5A Mouse anti-Mouse Monoclonal (pTyr694) (5F6.F1) Antibody
Mouse, Rat, Human
ELISA, IF, IHC, WB
Unconjugated
1 mg/$2,600
STAT5A Antibody - Immunohistochemistry of Monoclonal Anti-Stat5 pY694 Antibody. Tissue: human breast tissue (40X). Fixation: formalin fixed paraffin embedded (FFPE). Antigen retrieval: steam sections in 0.1 M sodium citrate buffer, pH 6, for 20 min. Rinse with 1XTBST. Primary antibody: Anti-Stat5pY694 at 20 µg/mL. Localization: breast epithelium with moderate nuclear staining. Staining: Stat5 pY694 as precipitated red signal, with a hematoxylin purple nuclear counterstain.
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STAT5A Mouse anti-Mouse Monoclonal (pTyr694) (5F6.F1) Antibody
Mouse, Rat, Human
ELISA, IF, IHC, WB
Unconjugated
25 µl/$304
STAT5A Antibody - IHC of paraffin-embedded Human prostate tissue using anti-STAT5A mouse monoclonal antibody.
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STAT5A Mouse anti-Human Monoclonal (OTI11A9) Antibody
Human
Flo, IHC, IHC-P, WB
Unconjugated
100 µl/$434
STAT5A Antibody - Anti-STAT5A antibody IHC of human tonsil. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:100.
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STAT5A Rabbit anti-Human Polyclonal (aa745-794) Antibody
Mouse, Rat, Human
IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50 µl/$460
STAT5A Antibody - Immunohistochemical analysis of STAT5A (pS780) staining in human breast cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with hematoxylin and mounted with DPX.
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STAT5A Rabbit anti-Human Polyclonal (pSer780) Antibody
Human, Monkey
ICC, IF, IHC, IHC-P, IP, WB
Unconjugated
100 µl/$315
STAT5A Antibody - 1:100 staining human breast carcinoma tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.
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STAT5A Rabbit anti-Human Polyclonal (pSer725,pSer730) Antibody
Mouse, Rat, Human
IF, IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
STAT5A Antibody - Human Spleen: Formalin-Fixed, Paraffin-Embedded (FFPE)
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STAT5A Goat anti-Human Polyclonal (aa681-692) Antibody
Human
IHC-P, Peptide-ELISA, WB
Unconjugated
50 µg/$460
STAT5A Antibody - P-peptide - + Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue using STAT5A (Phospho-Ser725) antibody.
Select
STAT5A Rabbit anti-Human Polyclonal (pSer725) Antibody
Rat, Human
ELISA, IF, IHC, WB
Unconjugated
100 µg/$357
STAT5A Antibody - 1:200 staining human brain tissue by IHC-P. The tissue was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The tissue was then blocked and incubated with the antibody for 1.5 hours at 22° C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.
Select
STAT5A Rabbit anti-Human Polyclonal (pSer780) Antibody
Mouse, Rat, Human
IF, IHC, IP, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
STAT5A Antibody - 1:100 staining human liver tissue by IHC-P. The tissue was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The tissue was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.
Select
STAT5A Rabbit anti-Human Polyclonal (pTyr694) Antibody
Mouse, Rat, Human
IF, IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
STAT5A Antibody - Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.
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STAT5A Rabbit anti-Human Polyclonal (pTyr694) Antibody
Human
IF, IHC, IHC-P, WB
Unconjugated
400 µl/$393
Viewing 1-25 of 160 product results



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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).