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STAT4
signal transducer and activator of transcription 4
STAT4 is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is essential for mediating responses to IL12 in lymphocytes, and regulating the differentiation of T helper cells. Mutations in this gene may be associated with systemic lupus erythematosus and rheumatoid arthritis. Alternate splicing results in multiple transcript variants that encode the same protein.
| Gene Name: | signal transducer and activator of transcription 4 |
| Synonyms: | STAT4, SLEB11 |
| Target Sequences: | NM_003151 NP_003142.1 Q14765 |
Publications (1)
1
A toolbox of immunoprecipitation-grade monoclonal antibodies to human transcription factors. Venkataraman A, Yang K, Irizarry J, Mackiewicz M, Mita P, Kuang Z, Xue L, Ghosh D, Liu S, Ramos P, Hu S, Bayron Kain D, Keegan S, Saul R, Colantonio S, Zhang H, Behn FP, Song G, Albino E, Asencio L, Ramos L, Lugo L, Morell G, Rivera J, Ruiz K, Almodovar R, Nazario L, Murphy K, Vargas I, Rivera-Pacheco ZA, Rosa C, Vargas M, McDade J, Clark BS, Yoo S, Khambadkone SG, de Melo J, Stevanovic M, Jiang L, Li Y, Yap WY, Jones B, Tandon A, Campbell E, Montelione GT, Anderson S, Myers RM, Boeke JD, Fenyö. Nature methods. 2018 May;15:330-338. [Full Text Article]
[PubMed:29638227]
[PMC:PMC6063793]
Related Antibodies: LS-B5539.
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STAT4
(126)
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(105)
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STAT4 Mouse anti-Human Monoclonal (1C2-1C12) Antibody
Human
ELISA, IF, IHC, IHC-P, IP, WB
Unconjugated
50 µg/$460
STAT4 Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Human
IHC, IHC-P, WB
Unconjugated
50 µl/$460
STAT4 Rabbit anti-Human Polyclonal (pTyr693) Antibody
Rabbit, Mouse, Dog, Sheep, Rat, Pig, Human
IHC, IHC-P, WB
Unconjugated
100 µl/$315
Sandwich
96-Well Strip Plate
Human
0.313 - 20 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$768
STAT4 Mouse anti-Human Monoclonal (OTI2F3) Antibody
Human
Flo, IF, IHC, IHC-P, WB
Unconjugated
100 µl/$434
STAT4 Mouse anti-Human Monoclonal (Carrier-free) (OTI2F3) Antibody
Human
Flo, IF, IHC, WB
Unconjugated, Carrier-free
100 µg/$511
STAT4 Mouse anti-Human Monoclonal (OTI 1H3) Antibody
Human
IF, IHC, IHC-P, WB
Unconjugated
100 µl/$434
STAT4 Mouse anti-Human Monoclonal (Carrier-free) (OTI 1H3) Antibody
Human
IF, IHC, WB
Unconjugated, Carrier-free
100 µg/$511
STAT4 Mouse anti-Human Monoclonal (OTI4H6) Antibody
Human
Flo, IHC, IHC-P, WB
Unconjugated
100 µl/$434
STAT4 Mouse anti-Human Monoclonal (Carrier-free) (OTI4H6) Antibody
Human
Flo, IHC, WB
Unconjugated, Carrier-free
100 µg/$511
STAT4 Mouse anti-Human Monoclonal (OTI1G9) Antibody
Human
Flo, IF, WB
Unconjugated
100 µl/$434
STAT4 Rabbit anti-Human Polyclonal (630-710 aa) Antibody
Mouse, Rat, Human, Monkey
ELISA, IHC, IP, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
STAT4 Rabbit anti-Human Polyclonal (pTyr693) Antibody
Mouse, Rat, Human
IHC, IHC-P, IP, Peptide-ELISA, WB
Unconjugated
50 µl/$334; 100 µl/$397
STAT4 Rabbit anti-Human Polyclonal (pTyr693) Antibody
Mouse, Rat, Human
IHC, IHC-P, IP, WB
Unconjugated
50 µl/$328; 100 µl/$419
STAT4 Mouse anti-Human Monoclonal (aa633-652) (Carrier-free) (OTI2A2) Antibody
Human
IHC, WB
Unconjugated, Carrier-free
100 µg/$511
STAT4 Mouse anti-Human Monoclonal (OTI3B6) Antibody
Human
Flo, IF, IHC, IHC-P, WB
Unconjugated
100 µl/$434
STAT4 Mouse anti-Human Monoclonal (Carrier-free) (OTI3B6) Antibody
Human
Flo, IF, IHC, WB
Unconjugated, Carrier-free
100 µg/$511
STAT4 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF, IHC, IHC-P, WB
Unconjugated
50 µg/$294; 100 µg/$360
STAT4 Mouse anti-Human Monoclonal (OTI1B1) Antibody
Human
Flo, IHC, IHC-P, WB
Unconjugated
100 µl/$434
STAT4 Mouse anti-Human Monoclonal (OTI4F9) Antibody
Human
Flo, IHC, IHC-P, WB
Unconjugated
100 µl/$434
STAT4 Rabbit anti-Human Monoclonal (Lys151) Antibody
Mouse, Rat, Human
WB
Unconjugated
100 µl/$688
STAT4 Rabbit anti-Human Polyclonal (pTyr693) Antibody
Mouse, Rat, Human
IF, IHC, IP, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
STAT4 Rabbit anti-Human Polyclonal (aa666-695) Antibody
Human
ELISA, IF, IHC, WB
Unconjugated
200 µl/$734
STAT4 Rabbit anti-Human Polyclonal (aa666-695) Antibody
Human
IF, IHC, IHC-P, WB
Unconjugated
400 µl/$393
STAT4 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF, IHC, WB
Unconjugated
100 µg/$341
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