Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
STAT3, Acute-phase response factor, APRF, DNA-binding protein APRF, HIES
Mouse, Human, Rat, Chicken
(tested or 100% immunogen sequence identity)
Protein A purified
Western blot (1:1000)
STAT3 antibody was raised against synthetic phosphopeptide corresponding to residues around Tyr705 of mouse Stat3 (KLH coupled).
Detects endogenous levels of mouse Stat3 only when phosphorylated at tyrosine 705. Does not appreciably cross-react with the corresponding phospho-tyrosines of other Stat proteins. Species cross-reactivity: Chicken, mouse, human and rat.
Suitable for use in ELISA, Western Blot, Immunoprecipitation, and Immunocytochemistry. Flow Cytometry: 1:50. Western Blot: 1:1000. Immunocytochemistry (ICC): 1:50. Immunoprecipitation: 1:100.
10 mM HEPES, pH 7.5, 150 mM NaCl, 0.1 mg/ml BSA, 50% Glycerol, No preservatives added
Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.
STAT3 is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is activated through phosphorylation in response to various cytokines and growth factors including IFNs, EGF, IL5, IL6, HGF, LIF and BMP2.