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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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STAT3 Antibody (phospho‑Tyr705) LS‑C10385
STAT3 antibody LS-C10385 is an unconjugated rabbit polyclonal antibody to STAT3 from human, mouse, rat and other species. Validated for ELISA, ICC, IP and WB.
Antibody
Catalog
Size
Price
LS-C10385-100
100 µl
$575

Popular STAT3 Products

Anti-STAT3 antibody IHC of human liver. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B4102 dilution 1:200.
Species: Human
Applications: IHC, IHC - Paraffin, Western blot, ELISA
Anti-STAT3 antibody IHC of human thymus. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B4693 concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Species: Human, Monkey, Mouse, Rat, Bat, Bovine, Dog, Horse, Pig, Rabbit
Applications: IHC, IHC - Paraffin, Western blot
Anti-STAT3 antibody IHC staining of human skin. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Species: Mouse, Human, Rat
Applications: IHC, IHC - Paraffin, Western blot, Immunoprecipitation
Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.
Species: Human
Applications: IHC, IHC - Paraffin, Western blot
Antibody
Species: Human, Mouse, Rat
Applications: ICC, Western blot, Immunoprecipitation, Flow Cytometry, ELISA

Product Description

STAT3 antibody LS-C10385 is an unconjugated rabbit polyclonal antibody to STAT3 from human, mouse, rat and other species. Validated for ELISA, ICC, IP and WB.

Specifications

Target
Mouse STAT3
Synonyms
STAT3, Acute-phase response factor, APRF, DNA-binding protein APRF, HIES
Host
Rabbit
Reactivity
Mouse, Human, Rat, Chicken (tested or 100% immunogen sequence identity)
Clonality
IgG Polyclonal
Conjugations
Unconjugated
Purification
Protein A purified
Modifications
Unmodified
Applications
  • ICC (1:50)
  • Western blot (1:1000)
  • Immunoprecipitation (1:100)
  • ELISA
Immunogen
STAT3 antibody was raised against synthetic phosphopeptide corresponding to residues around Tyr705 of mouse Stat3 (KLH coupled).
Epitope
pTyr705
Specificity
Detects endogenous levels of mouse Stat3 only when phosphorylated at tyrosine 705. Does not appreciably cross-react with the corresponding phospho-tyrosines of other Stat proteins. Species cross-reactivity: Chicken, mouse, human and rat.
Usage
Suitable for use in ELISA, Western Blot, Immunoprecipitation, and Immunocytochemistry. Flow Cytometry: 1:50. Western Blot: 1:1000. Immunocytochemistry (ICC): 1:50. Immunoprecipitation: 1:100.
Presentation
10 mM HEPES, pH 7.5, 150 mM NaCl, 0.1 mg/ml BSA, 50% Glycerol, No preservatives added
Storage
Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.
Restrictions
For research use only.
About STAT3
STAT3 is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is activated through phosphorylation in response to various cytokines and growth factors including IFNs, EGF, IL5, IL6, HGF, LIF and BMP2. P40763 NM_003150 NP_003141.2


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Requested From: United States
Date Requested: 10/19/2018

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