Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
(applications tested for the base form of this product only)
STAT2 antibody was raised against fusion Protein corresponding to residues 672-925 of murine STAT2.
Recognizes mouse STAT2, Mr 130kD.
Western Blot: 0.5-2 ug/ul. 3T3 cell lysate probed with anti-STAT2 (0.5 ug/ul). Immunocytochemistry: Positive immunostaining reported on fresh cells fixed with 3.7% formaldehyde and permeabilized with 0.2% Triton1.
0.1 M Tris-Glycine, pH 7.4, 0.15 M NaCl, 0.05% Sodium Azide, 30% Glycerol
Short term: 4°C; Long term: Add glycerol (40-50%) -20°C.
STAT2 is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators.