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| Catalog Number | Size | Price |
|---|---|---|
| LS-B4920-50 | 50 µg (0.5 mg/ml) | $485 |
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IHC‑plus™ Polyclonal Goat anti‑Human STAP2 Antibody (aa436‑449, IHC, WB) LS‑B4920
IHC‑plus™ Polyclonal Goat anti‑Human STAP2 Antibody (aa436‑449, IHC, WB) LS‑B4920
Note: This antibody replaces LS-C55533
Antibody:
STAP2 Goat anti-Human Polyclonal (aa436-449) Antibody
Application:
IHC, IHC-P, WB, Peptide-ELISA
Reactivity:
Human, Monkey
Format:
Unconjugated, Unmodified
Toll Free North America
206-374-1102
206-374-1102For Research Use Only
Overview
Antibody:
STAP2 Goat anti-Human Polyclonal (aa436-449) Antibody
Application:
IHC, IHC-P, WB, Peptide-ELISA
Reactivity:
Human, Monkey
Format:
Unconjugated, Unmodified
Specifications
Description
STAP2 antibody LS-B4920 is an unconjugated goat polyclonal antibody to STAP2 (aa436-449) from human. It is reactive with human and monkey. Validated for IHC, Peptide-ELISA and WB. Tested on 20 paraffin-embedded human tissues. Cited in 4 publications.
Target
Human STAP2
Synonyms
STAP2 | BRK substrate | BKS | Brk kinase substrate | STAP-2 | Breast tumor kinase substrate
Host
Goat
Reactivity
Human, Monkey
(tested or 100% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated
Purification
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Modifications
Unmodified
Immunogen
Peptide with sequence C-ELQKKLEKRRALEH, from the C-Terminus of protein sequence according to NP_060190.2NP_001013863.1.
Epitope
aa436-449
Specificity
Human STAP2. This antibody is expected to recognise isoforms 1 (NP_060190.2) and isoform 2 (NP_001013863.1).
Applications
- IHC
- IHC - Paraffin (3.75 µg/ml)
- Western blot (0.5 - 1.5 µg/ml)
- Peptide Enzyme-Linked Immunosorbent Assay (1:128000)
|
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents
ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
|
Presentation
TBS, pH 7.3, 0.02% Sodium Azide, 0.5% BSA
Storage
Aliquot and store at -20°C. Avoid freeze-thaw cycles.
Restrictions
For research use only. Intended for use by laboratory professionals.
About STAP2
Validation
Anti-STAP2 antibody IHC of human prostate. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 3.75 ug/ml.
Anti-STAP2 antibody IHC of human prostate. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 3.75 ug/ml.
Anti-STAP2 antibody IHC of human small intestine. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 3.75 ug/ml.
Anti-STAP2 antibody IHC of human small intestine. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 3.75 ug/ml.
Anti-STAP2 antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 3.75 ug/ml.
Anti-STAP2 antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 3.75 ug/ml.
See More About...
LSBio Ratings
IHC-plus™ STAP2 Antibody (aa436-449) for IHC, WB/Western LS-B4920 has an LSBio Rating of
Publications (4.3)
Laboratory Validation Score (4)
Learn more about The LSBio Ratings Algorithm
Publications (4)
STAP-2 is phosphorylated at tyrosine-250 by Brk and modulates Brk-mediated STAT3 activation. Ikeda O, Miyasaka Y, Sekine Y, Mizushima A, Muromoto R, Nanbo A, Yoshimura A, Matsuda T. Biochemical and biophysical research communications. 2009 384:71-5.
Signal-transducing adaptor protein-2 regulates stromal cell-derived factor-1 alpha-induced chemotaxis in T cells. Sekine Y, Ikeda O, Tsuji S, Yamamoto C, Muromoto R, Nanbo A, Oritani K, Yoshimura A, Matsuda T. Journal of immunology (Baltimore, Md. : 1950). 2009 183:7966-74.
Interactions of STAP-2 with Brk and STAT3 participate in cell growth of human breast cancer cells. Ikeda O, Sekine Y, Mizushima A, Nakasuji M, Miyasaka Y, Yamamoto C, Muromoto R, Nanbo A, Oritani K, Yoshimura A, Matsuda T. The Journal of biological chemistry. 2010 285:38093-103.
Involvement of STAP-2 in Brk-mediated phosphorylation and activation of STAT5 in breast cancer cells. Ikeda O, Mizushima A, Sekine Y, Yamamoto C, Muromoto R, Nanbo A, Oritani K, Yoshimura A, Matsuda T. Cancer science. 2011 102:756-61.
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Featured Products
Species:
Human, Monkey, Bat
Applications:
IHC - Paraffin
Reactivity:
Mouse
Range:
0.156-10 ng/ml
Species:
Clostridium botulinum
Applications:
Western blot, ELISA
Request SDS/MSDS
To request an SDS/MSDS form for this product, please contact our Technical Support department at:
Technical.Support@LSBio.com
Requested From: United States
Date Requested: 4/19/2024
Date Requested: 4/19/2024
