Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Human (tested or 100% immunogen sequence identity)
Ammonium sulfate precipitation
IHC - Frozen
Specificity and Use
Identification of CD15+ granulocytes by indirect immunofluorescence or by FC analysis Identification of CD15+ granulocytes present in frozen sections. Phenotyping of lymphomas and leukemias. Inhibition of neutrophil phagocytosis and bactericidal activity. Precipitation studies of the CD15 antigen. The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.
10 mM sodium azide, 1 mg/ml BSA.
For research use only.
About SSEA-1 / Lewis x / CD15
Also known as CD15, Lewis x, and 3-fucosyl-N-acetyl-lactosamine. It is synthezised by Fucosyltransferase 4 (FUT4).