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Binds to extracellular matrix proteins. Binds to pathogen-associated molecular patterns (PAMPs) present on the cell walls of Gram-positive and Gram-negative bacteria and fungi, behaving as a pattern recognition receptor (PRR). Induces bacterial and fungal aggregation and subsequent inhibition of PAMP-induced cytokine release. Does not possess intrinsic bactericidal activity. May play a role in the innate defense and homeostasis of certain epithelial surfaces.
Gene Name: | scavenger receptor cysteine rich domain containing (5 domains) |
Synonyms: | SSC5D |
Target Sequences: | NM_001144950 NP_001138422.1 A1L4H1 |
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