Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
SSB Antibody, Autoantigen La Antibody, La Antibody, La ribonucleoprotein Antibody, Lupus La antigen Antibody, SS-B Antibody, SS-B/La protein Antibody, La autoantigen Antibody, LARP3 Antibody, Lupus La protein Antibody
SSB / La is involved in diverse aspects of RNA metabolism, including binding and protecting poly(U) termini of nascent RNA polymerase III transcripts from exonuclease digestion, processing 5' and 3' ends of pre-tRNA precursors, acting as an RNA chaperone, and binding viral RNAs associated with hepatitis C virus. Autoantibodies reacting with this protein are found in the sera of patients with Sjogren syndrome and systemic lupus erythematosus.
Formalin-fixed and paraffin-embedded human hepatocarcinoma reacted with SSB Antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
Western blot of SSB Antibody in K562, HeLa, 293 cell line lysates (35 ug/lane). SSB (arrow) was detected using the purified antibody.
Requested From: United States
Date Requested: 12/4/2016