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Anti-SRY Antibody (clone 2C7) LS-C174165

Catalog Size Price
LS-C174165-100 100 µl (1 mg/ml) Unavailable

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100% Guaranteed
Mouse Monoclonal [clone 2C7] (IgG1) to Human SRY
Human
Western blot
Unconjugated

Details

Human SRY
Mouse
Human (tested or 100% immunogen sequence identity)
IgG1 Monoclonal [2C7]
Unconjugated
Protein A/G purified
Unmodified

Applications

Western blot (1:1000)

Specificity and Use

SRY antibody was raised against full length human recombinant protein of human SRY(NP_003131) produced in E. coli.
Human SRY

Packaging

PBS, pH 7.3, 1% BSA, 50% glycerol, 0.02% sodium azide
Store at -20°C. Avoid freeze-thaw cycles.
For research use only.

About SRY

Q05066 NM_003140 NP_003131.1

SRY Antibody, Sex determining region protein Antibody, Sex-determining region on Y Antibody, SRXX1 Antibody, SRXY1 Antibody, TDF Antibody, Testis-determining factor Antibody, Sex determining region Y Antibody, TDY Antibody

Transcriptional regulator that controls a genetic switch in male development. It is necessary and sufficient for initiating male sex determination by directing the development of supporting cell precursors (pre-Sertoli cells) as Sertoli rather than granulosa cells (By similarity). In male adult brain involved in the maintenance of motor functions of dopaminergic neurons (By similarity). Involved in different aspects of gene regulation including promoter activation or repression (By similarity).

Western blot

Western blot
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY SRY (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-SRY.

Requested From: 
Date Requested: 8/16/2017

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