SRSF1 / SF2

serine/arginine-rich splicing factor 1

Plays a role in preventing exon skipping, ensuring the accuracy of splicing and regulating alternative splicing. Interacts with other spliceosomal components, via the RS domains, to form a bridge between the 5'- and 3'-splice site binding components, U1 snRNP and U2AF. Can stimulate binding of U1 snRNP to a 5'-splice site-containing pre-mRNA. Binds to purine-rich RNA sequences, either the octamer, 5'-RGAAGAAC-3' (r=A or G) or the decamers, AGGACAGAGC/AGGACGAAGC. Binds preferentially to the 5'-CGAGGCG-3' motif in vitro. Three copies of the octamer constitute a powerful splicing enhancer in vitro, the ASF/SF2 splicing enhancer (ASE) which can specifically activate ASE-dependent splicing. Isoform ASF-2 and isoform ASF-3 act as splicing repressors. May function as export adapter involved in mRNA nuclear export through the TAP/NXF1 pathway.

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Products

Antibodies (46)

Proteins (12)

ELISA Kits (6)

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Custom (4)

Over-Expression Lysate (6)

Primary (46)

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Target

SRSF1 / SF2 (64)

Reactivity

Human (48)

Mouse (25)

Rat (24)

Bat (7)

Bovine (7)

Chicken (7)

Chimpanzee (7)

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Hamster (7)

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Orangutan (7)

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IHC (12)

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rabbit (34)

mouse (12)

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IHCPlus (3)

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monoclonal mc (12)

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aa16-224 (8)

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293T Cells (3)

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IHC-plus™ SRSF1 / SF2 Antibody (N-Terminus) LS-B2340

(5.0) Rating

(1) Publication(s)

Antibody:

SRSF1 / SF2 Mouse anti-Human Monoclonal (N-Terminus) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IF, IHC, IHC-P, IP, WB

Format:

Unconjugated

Price:

50 µg/$485

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SRSF1 / SF2 Antibody (HRP) LS-C549543

Antibody:

SRSF1 / SF2 Mouse anti-Human Monoclonal (HRP) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IF, IP, WB

Format:

HRP Conjugated

Price:

100 µl/$1,063

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SRSF1 / SF2 Antibody (Biotin) LS-C529453

Antibody:

SRSF1 / SF2 Mouse anti-Human Monoclonal (Biotin) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IF, IP, WB

Format:

Biotin Conjugated

Price:

100 µl/$1,063

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SRSF1 / SF2 Antibody (FITC) LS-C539373

Antibody:

SRSF1 / SF2 Mouse anti-Human Monoclonal (FITC) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IF, IP, WB

Format:

FITC Conjugated

Price:

100 µl/$1,063

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SRSF1 / SF2 Antibody (APC) LS-C519298

Antibody:

SRSF1 / SF2 Mouse anti-Human Monoclonal (APC) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IF, IP, WB

Format:

APC Conjugated

Price:

100 µl/$1,063

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SRSF1 / SF2 Antibody (PE) LS-C657519

Antibody:

SRSF1 / SF2 Mouse anti-Human Monoclonal (PE) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IF, IP, WB

Format:

PE Conjugated

Price:

100 µl/$1,063

• Unconjugated
• HRP
• Biotin
• FITC
• APC
• PE

• Unconjugated
• HRP
• Biotin
• More...
  • FITC
  • APC
  • PE

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SRSF1 / SF2 Antibody (aa158-186) LS-C169019

Antibody:

SRSF1 / SF2 Rabbit anti-Human Polyclonal (aa158-186) Antibody

Reactivity:

Human

Applications:

Flo, IHC, IHC-P, WB

Format:

Unconjugated

Price:

400 µl/$393

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IHC-plus™ SRSF1 / SF2 Antibody (N-Terminus) LS-B3263

(4.0) Rating

Antibody:

SRSF1 / SF2 Mouse anti-Human Monoclonal (N-Terminus) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IF, IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µg/$485

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SRSF1 / SF2 Antibody (FITC) LS-C539374

Antibody:

SRSF1 / SF2 Mouse anti-Human Monoclonal (FITC) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IF, WB

Format:

FITC Conjugated

Price:

100 µl/$1,017

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SRSF1 / SF2 Antibody (APC) LS-C519299

Antibody:

SRSF1 / SF2 Mouse anti-Human Monoclonal (APC) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IF, WB

Format:

APC Conjugated

Price:

100 µl/$1,017

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SRSF1 / SF2 Antibody (PE) LS-C657517

Antibody:

SRSF1 / SF2 Mouse anti-Human Monoclonal (PE) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IF, WB

Format:

PE Conjugated

Price:

100 µl/$1,017

• Unconjugated
• FITC
• APC
• PE

• Unconjugated
• FITC
• APC
• More...
  • PE

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Human SRSF1 / SF2 Protein (Recombinant His-T7) (aa16-224) - LS-G24709

Source:

E. coli

Tag:

His-T7

Molecular Weight:

27.2 kDa

Price:

10 µg/$259; 50 µg/$332; 100 µg/$487; 200 µg/$610; 1 mg/$1,567; 500 µg/$1,167; 5 mg/$2,498; 2 mg/$1,737

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Human SRSF1 / SF2 (Sandwich ELISA) ELISA Kit - LS-F12658

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.312 - 20 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$783

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SRSF1 / SF2 Antibody (aa6-33) LS-C357591

Antibody:

SRSF1 / SF2 Rabbit anti-Human Polyclonal (aa6-33) Antibody

Reactivity:

Xenopus, Rat, Hamster, Mouse, Dog, Guinea pig, Bovine, Bat, Pig, Gibbon, Human, Monkey, Chimpanzee, Orangutan

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

10 µg/$318; 100 µg/$470

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SRSF1 / SF2 Antibody LS-C806212

Antibody:

SRSF1 / SF2 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human, Monkey

Applications:

IHC, Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µl/$379; 200 µl/$421

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IHC-plus™ SRSF1 / SF2 Antibody (aa1-50) LS-B15063

(4.0) Rating

Antibody:

SRSF1 / SF2 Rabbit anti-Human Polyclonal (aa1-50) Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, IP, WB

Format:

Unconjugated

Price:

50 µl/$460

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SRSF1 / SF2 Antibody LS-C482298

Antibody:

SRSF1 / SF2 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ICC, IF, IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µl/$286; 100 µl/$321; 200 µl/$386

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SRSF1 / SF2 Antibody (aa161-210) LS-C30325

Antibody:

SRSF1 / SF2 Rabbit anti-Human Polyclonal (aa161-210) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$424

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SRSF1 / SF2 Antibody LS-C331609

Antibody:

SRSF1 / SF2 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IF, IHC, WB

Format:

Unconjugated

Price:

20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503

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Human SRSF1 / SF2 Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G66635

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

27.6 kDa

Price:

20 µg/$1,107

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SRSF1 / SF2 Antibody LS-C490083

Antibody:

SRSF1 / SF2 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

100 µg/$575

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SRSF1 / SF2 Antibody (aa11-38) LS-C169020

Antibody:

SRSF1 / SF2 Rabbit anti-Human Polyclonal (aa11-38) Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

400 µl/$393

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SRSF1 / SF2 Antibody (aa1-248) LS-C376588

Antibody:

SRSF1 / SF2 Rabbit anti-Human Polyclonal (aa1-248) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, IHC-P

Format:

Unconjugated

Price:

50 µl/$294; 100 µl/$360

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SRSF1 / SF2 Antibody LS-C664370

Antibody:

SRSF1 / SF2 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IP, WB

Format:

Unconjugated

Price:

100 µg/$341

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SRSF1 / SF2 Antibody LS-C193020

Antibody:

SRSF1 / SF2 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC, WB

Format:

Unconjugated

Price:

50 µl/$356; 100 µl/$461

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