LSBio
LSBio
Products
Services
Research Areas
Resources
Contact Us
Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

LSBio
2401 Fourth Avenue Suite 900
Seattle WA 98121

Phone: 866-819-4732 (Toll Free North America)
206-374-1102 (International)

Fax: 866-206-6909 (Toll Free North America)
206-577-4565 (International)

How to Buy - Details about how to buy our products.

Orders@LSBio.com - To submit a new order.

Customer.Support@LSBio.com - To submit questions about existing orders, pricing, availability, bulk quotes, proforma invoice requests, or other billing issues.

Technical.Support@LSBio.com - To request technical information requests about an LSBio product or its application.

Sales@LSBio.com - To request information about fee-for-service contract IHC studies, IHC reports, distribution agreements, or general business development.

Worldwide Distributors List - To find your local distributor if you're not within the United States.
Products
Services
Research Areas
Resources
Contact Us
SRSF1 / SF2 Antibody LS‑C10324
SF2 antibody LS-C10324 is an unconjugated rabbit polyclonal antibody to SF2 (SRSF1) from human, mouse, rat and other species. Validated for ELISA and WB.
Antibody
Catalog
Size
Price
LS-C10324-50
50 µg
$345
LS-C10324-100
100 µg
$465

Popular SRSF1 / SF2 Products

Anti-SF2 antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B2340 concentration 5 ug/ml.
Species: Human, Mouse, Rat
Applications: IHC, IHC - Paraffin, Immunofluorescence, Western blot, Immunoprecipitation
Anti-SF2 antibody IHC of human breast. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B3263 concentration 10 ug/ml.
Species: Human, Mouse, Rat
Applications: IHC, IHC - Paraffin, Immunofluorescence, Western blot
Formalin-fixed and paraffin-embedded human colon carcinoma reacted with SFRS1 Antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
Species: Human
Applications: IHC, IHC - Paraffin, Western blot, Flow Cytometry
A: Marker, B: HepG2 Cell Lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Species: Human, Monkey, Mouse, Rat, Bat, Bovine, Dog, Guinea pig, Hamster, Horse, Pig, Chicken, Xenopus, Zebrafish
Applications: Western blot
SF2 antibody IHC-paraffin: Rat Brain Tissue.
Species: Human, Chimpanzee, Orangutan, Gibbon, Monkey, Mouse, Rat, Bat, Bovine, Dog, Guinea pig, Hamster, Pig, Xenopus
Applications: IHC, IHC - Paraffin, Western blot

Product Description

SF2 antibody LS-C10324 is an unconjugated rabbit polyclonal antibody to SF2 (SRSF1) from human, mouse, rat and other species. Validated for ELISA and WB.
About SRSF1 / SF2
Plays a role in preventing exon skipping, ensuring the accuracy of splicing and regulating alternative splicing. Interacts with other spliceosomal components, via the RS domains, to form a bridge between the 5'- and 3'-splice site binding components, U1 snRNP and U2AF. Can stimulate binding of U1 snRNP to a 5'-splice site-containing pre-mRNA. Binds to purine-rich RNA sequences, either the octamer, 5'-RGAAGAAC-3' (r=A or G) or the decamers, AGGACAGAGC/AGGACGAAGC. Q07955 NM_006924 NP_008855.1

SRSF1 Antibody, Alternative-splicing factor 1 Antibody, ASF Antibody, SF2 Antibody, SF2p33 Antibody, SFRS1 Antibody, Splicing factor 2 Antibody, ASF-1 Antibody, SR splicing factor 1 Antibody, SRp30a Antibody


Specifications

Target
Human SRSF1 / SF2
Host
Rabbit
Reactivity
Human, Monkey, Mouse, Rat, Bovine, Dog, Hamster, Horse, Pig, Chicken, Xenopus, Zebrafish (tested or 100% immunogen sequence identity)
Predicted
Bat, Rabbit (at least 90% immunogen sequence identity)
Clonality
IgG Polyclonal
Conjugations
Unconjugated
Purification
Immunoaffinity purified
Modifications
Unmodified
Applications
  • Western blot
  • ELISA
Immunogen
SRSF1 / SF2 antibody was raised against synthetic peptide corresponding to LDNTKFRSHEGET of humanSFRS1 (KLH). MW: 27.7kD. Percent identity by BLAST analysis: Human, Gorilla, Orangutan, Gibbon, Monkey, Marmoset, Mouse, Rat, Hamster, Elephant, Panda, Dog, Bovine, Horse, Pig, Chicken, Platypus, Xenopus, Salmon, Pufferfish, Zebrafish (100%); Bat, Rabbit, Seq squirt, Nematode (92%); Opossum, Eye worm, Sea anemone, Trichoplax (85%).
Specificity
Recognizes Splicing Factor, Arginine/Serine-Rich 1. Cross-reacts with SFRS9. Species cross-reactivity: Human and rodent.
Usage
Suitable for use in ELISA. ELISA (Serum Titer): 1:250000. Western Blot: Preliminary results: Human placenta 50, 65kD, Human cerebellum 50kD.
Presentation
PBS, 0.02% Sodium Azide, 40% Glycerol
Storage
Short term: -20°C; Long term: -20°C.
Restrictions
For research use only.

Publications (0)


Customer Reviews (0)


Requested From: United States
Date Requested: 9/24/2018

Get Social With Us!
Follow us on Facebook Follow us on Google+ Follow us on LinkedIn PSL Alliance Member
Copyright © 2018 LifeSpan BioSciences, Inc. All Rights Reserved Privacy Policy