Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Mouse Monoclonal [clone 6H5] (IgG1,k) to Human SRPK1
IHC - Paraffin, Western blot, ELISA
Human (tested or 100% immunogen sequence identity)
IgG1,k Monoclonal [6H5]
Purified from ascites by Protein A
IHC - Paraffin (5 µg/ml)
Specificity and Use
SRPK1 antibody was raised against sRPK1 (AAH38292, 371 a.a. ~ 470 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Western Blot (Cell lysate) - positive control HepG2. Western Blot (Cell lysate) - positive control IMR-32. Western Blot (Transfected lysate) - positive control transfected 293T cell line. Sandwich ELISA (Recombinant protein).
PBS, pH 7.4
Store at -20°C. Aliquot to avoid freeze/thaw cycles.
SRPK1 Antibody, SFRS protein kinase 1 Antibody, SFRSK1 Antibody, SR-protein-specific kinase 1 Antibody, SRSF protein kinase 1 Antibody
Serine/arginine-rich protein-specific kinase which specifically phosphorylates its substrates at serine residues located in regions rich in arginine/serine dipeptides, known as RS domains and is involved in the phosphorylation of SR splicing factors and the regulation of splicing. Plays a central role in the regulatory network for splicing, controlling the intranuclear distribution of splicing factors in interphase cells and the reorganization of nuclear speckles during mitosis.