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| Catalog Number | Size | Price |
|---|---|---|
| LS-B1609-1 | 1 Each (500 µg/µl) | $485 |
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IHC‑plus™ Polyclonal Rabbit anti‑Human SREBF2 / SREBP2 Antibody (aa455‑469, IHC, WB) LS‑B1609
IHC‑plus™ Polyclonal Rabbit anti‑Human SREBF2 / SREBP2 Antibody (aa455‑469, IHC, WB) LS‑B1609
Note: This antibody replaces LS-C11180
Antibody:
SREBF2 / SREBP2 Rabbit anti-Human Polyclonal (aa455-469) Antibody
Application:
IHC-P, ICC, WB
Reactivity:
Human, Monkey, Mouse, Rat, Bovine, Dog, Hamster, Horse, Pig, Chicken
Format:
Unconjugated, Unmodified
Toll Free North America
206-374-1102
206-374-1102For Research Use Only
Overview
Antibody:
SREBF2 / SREBP2 Rabbit anti-Human Polyclonal (aa455-469) Antibody
Application:
IHC-P, ICC, WB
Reactivity:
Human, Monkey, Mouse, Rat, Bovine, Dog, Hamster, Horse, Pig, Chicken
Format:
Unconjugated, Unmodified
Specifications
Description
SREBP2 antibody LS-B1609 is an unconjugated rabbit polyclonal antibody to SREBP2 (SREBF2) (aa455-469) from human. It is reactive with human, mouse, rat and other species. Validated for ICC, IHC and WB. Tested on 20 paraffin-embedded human tissues. Cited in 2 publications.
Target
Human SREBF2 / SREBP2
Synonyms
SREBF2 | SREBP2 | SREBP-2 | BHLHd2
Host
Rabbit
Reactivity
Human, Monkey, Mouse, Rat, Bovine, Dog, Hamster, Horse, Pig, Chicken
(tested or 100% immunogen sequence identity)
Predicted
Bat, Xenopus (at least 90% immunogen sequence identity)
Clonality
IgG
Polyclonal
Conjugations
Unconjugated
Purification
Affinity purified
Modifications
Unmodified
Immunogen
Human SREBP-2 amino acids 455-469 (SPLLDDAKVKDEPDS). Percent identity by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Mouse, Rat, Dog, Bovine, Hamster, Elephant, Panda, Horse, Pig, Turkey, Chicken, Platypus, Lizard (100%); Bat, Xenopus (93%).
Epitope
aa455-469
Specificity
human SREBP-2 amino acids 455-469 (SPLLDDAKVKDEPDS)
Applications
- IHC - Paraffin (5 µg/ml)
- ICC (1:150)
- Western blot (1:200)
|
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents
ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
|
Usage
Immunohistochemistry: LS-B1609 was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for LS-B1609 was determined to be 5 ug/ml.
Presentation
PBS, pH 7.2, 0.02% Sodium Azide, 50% Glycerol
Storage
Aliquot and store at -20°C.
Restrictions
For research use only. Intended for use by laboratory professionals.
About SREBF2 / SREBP2
Validation
Nuclear Staining in Human Lung: Formalin-Fixed, Paraffin-Embedded (FFPE)
Nuclear Staining in Human Lung: Formalin-Fixed, Paraffin-Embedded (FFPE)
Nuclear Staining in Human Skin: Formalin-Fixed, Paraffin-Embedded (FFPE)
Nuclear Staining in Human Skin: Formalin-Fixed, Paraffin-Embedded (FFPE)
Nuclear Staining in HumanSpleen: Formalin-Fixed, Paraffin-Embedded (FFPE)
Nuclear Staining in HumanSpleen: Formalin-Fixed, Paraffin-Embedded (FFPE)
Nuclear Staining in Human Testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
Nuclear Staining in Human Testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
Nuclear Staining in Human Breast: Formalin-Fixed, Paraffin-Embedded (FFPE)
Nuclear Staining in Human Breast: Formalin-Fixed, Paraffin-Embedded (FFPE)
Nuclear Staining in Human Colon: Formalin-Fixed, Paraffin-Embedded (FFPE)
Nuclear Staining in Human Colon: Formalin-Fixed, Paraffin-Embedded (FFPE)
See More About...
LSBio Ratings
IHC-plus™ SREBF2 / SREBP2 Antibody (aa455-469) for IHC, ICC, WB/Western LS-B1609 has an LSBio Rating of
Publications (4.1)
Laboratory Validation Score (4)
Learn more about The LSBio Ratings Algorithm
Publications (2)
Effect of cholesterol reduction on receptor signaling in neurons. Fukui K, Ferris HA, Kahn CR. The Journal of biological chemistry. 2015 290:26383-92. (WB; Mouse)
Loss of astrocyte cholesterol synthesis disrupts neuronal function and alters whole-body metabolism. Ferris HA, Perry RJ, Moreira GV, Shulman GI, Horton JD, Kahn CR. Proceedings of the National Academy of Sciences of the United States of America. 2017 January;114:1189-1194. (Human)
Customer Reviews (0)
Featured Products
Species:
Human, Mouse
Applications:
IHC, IHC - Paraffin, Western blot
Species:
Human
Applications:
IHC, IHC - Paraffin, Western blot
Species:
Human
Applications:
IHC, ICC, Immunofluorescence, Western blot, ELISA
Reactivity:
Human
Range:
0.312-20 ng/ml
Request SDS/MSDS
To request an SDS/MSDS form for this product, please contact our Technical Support department at:
Technical.Support@LSBio.com
Requested From: United States
Date Requested: 4/19/2024
Date Requested: 4/19/2024
