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Anti-SREBF2 / SREBP2 Antibody (aa455-469) IHC-plus™ LS-B1609

Note: This antibody replaces LS-C11180

Ordering

Wt. Vol. Conc. Price
- 1 ea - $450
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)
206-374-1102
866-206-6909
Orders@LSBio.com
 

Most Popular SREBF2 / SREBP2 Antibodies

Anti-SREBF2 / SREBP2 Antibody (aa434-483) IHC-plus™ LS-B1002
Rabbit Polyclonal to Human SREBF2 / SREBP2
Human, Monkey, Mouse, Rat, Bat, Bovine, Dog, Guinea pig, Hamster, Horse, Pig, Rabbit, Chicken
IHC - Paraffin, Western blot
Unconjugated
Immunohistochemistry Image
Anti-SREBF2 / SREBP2 Antibody (aa304-353) IHC-plus™ LS-B4695
Rabbit Polyclonal to Human SREBF2 / SREBP2
Human, Monkey, Mouse, Rat, Bat, Bovine, Dog, Guinea pig, Hamster, Horse, Pig, Chicken
IHC - Paraffin, Western blot
Unconjugated
Immunohistochemistry Image
Anti-SREBF2 / SREBP2 Antibody (aa399-427, APC) LS-C270344
Rabbit Polyclonal (IgG) to Human SREBF2 / SREBP2
Human
IHC, ICC, Immunofluorescence, Western blot, ELISA
APC Conjugated

100% Guaranteed 100% Guaranteed
Rabbit Polyclonal (IgG) to Human SREBF2 / SREBP2
Human, Monkey, Mouse, Rat, Bovine, Dog, Hamster, Horse, Pig, Chicken
IHC - Paraffin, ICC, Western blot
Unconjugated

Details

Human SREBF2 / SREBP2
Rabbit
Human, Monkey, Mouse, Rat, Bovine, Dog, Hamster, Horse, Pig, Chicken (tested or 100% immunogen sequence identity)
Bat, Xenopus (at least 90% immunogen sequence identity)
IgG Polyclonal
Unconjugated
Affinity purified
Unmodified

Applications

  • IHC - Paraffin (5 µg/ml)
  • ICC
  • Western blot

Specificity and Use

SREBF2 / SREBP2 antibody was raised against human SREBP-2 amino acids 455-469 (SPLLDDAKVKDEPDS). Percent identity by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Mouse, Rat, Dog, Bovine, Hamster, Elephant, Panda, Horse, Pig, Turkey, Chicken, Platypus, Lizard (100%); Bat, Xenopus (93%).
aa455-469
human SREBP-2 amino acids 455-469 (SPLLDDAKVKDEPDS)
Immunohistochemistry: LS-B1609 was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for LS-B1609 was determined to be 5 ug/ml.

Packaging

Tris buffered saline.
Long term: -20°C; Short term: +4°C. Avoid repeat freeze-thaw cycles.
For research use only.

About SREBF2 / SREBP2

Q12772 NM_004599 NP_004590.2

SREBF2 Antibody, SREBP2 Antibody, SREBP-2 Antibody, BHLHd2 Antibody

Transcriptional activator required for lipid homeostasis. Regulates transcription of the LDL receptor gene as well as the cholesterol and to a lesser degree the fatty acid synthesis pathway (By similarity). Binds the sterol regulatory element 1 (SRE-1) (5'-ATCACCCCAC-3') found in the flanking region of the LDRL and HMG-CoA synthase genes.

Immunohistochemistry

Immunohistochemistry
Anti-SREBP-2 antibody IHC of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B1609 concentration 5 ug/ml.

Western blot

Western blot
Lane 1: Human fibroblast cell lysate (60 ug); Lane 2: Rat brown fat homogenate (60 ug); Lane 3: Rat testis supernatant (60 ug)

Requested From: United States
Date Requested: 12/7/2016

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