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SPTLC2 / LCB2

serine palmitoyltransferase, long chain base subunit 2

Serine palmitoyltransferase (SPT). The heterodimer formed with LCB1/SPTLC1 constitutes the catalytic core. The composition of the serine palmitoyltransferase (SPT) complex determines the substrate preference. The SPTLC1-SPTLC2-SPTSSA complex shows a strong preference for C16-CoA substrate, while the SPTLC1-SPTLC2-SPTSSB complex displays a preference for C18-CoA substrate.

Gene Name: serine palmitoyltransferase, long chain base subunit 2
Synonyms: SPTLC2, HSN1C, HLCB2a, KIAA0526, LCB2, LCB2A, SPT 2, NSAN1C, SPT2, LCB 2, Serine palmitoyltransferase 2
Target Sequences: NM_004863 NP_004854.1 O15270

Publications (1)

1
Intestine-selective farnesoid X receptor inhibition improves obesity-related metabolic dysfunction. Jiang C, Xie C, Lv Y, Li J, Krausz KW, Shi J, Brocker CN, Desai D, Amin SG, Bisson WH, Liu Y, Gavrilova O, Patterson AD, Gonzalez FJ. Nature communications. 2015 6:10166. (ICC; Human) [Full Text Article] [PubMed:26670557] [PMC:PMC4682112] Related Antibodies: LS-B9514.

☰ Filters
Antibodies (37)
Proteins (6)
ELISA Kits (1)
Over-Expression Lysate (2)
Primary (37)
Recombinant (4)
Sandwich (1)
SPTLC2 / LCB2 (44)
Human (29)
Mouse (23)
Rat (6)
Bovine (3)
Chimpanzee (3)
Gibbon (3)
Guinea pig (3)
Hamster (3)
Monkey (3)
Pig (1)
Rabbit (3)
Sheep (1)
Xenopus (3)
Zebrafish (3)
IHC (3)
IHC-P (3)
WB (32)
ELISA (18)
ICC (1)
IF (2)
Peptide-ELISA (1)
rabbit (37)
Product Group
IHCPlus (2)
IgG (26)
polyclonal pc (37)
96-Well Strip Plate (1)
APC (1)
APC Conjugated (3)
Azide-free (2)
Biotin Conjugated (5)
Cy3 Conjugated (1)
Cy7 Conjugated (1)
FITC Conjugated (5)
HRP Conjugated (5)
PE Conjugated (3)
Unconjugated (14)
aa453-560 (8)
aa372-401 (7)
aa531-562 (7)
aa72-121 (4)
aa88-562 (4)
aa548-562 (1)
No (43)
Yes (1)
Tissue Homogenates (1)
GST (1)
GST, N-terminus (1)
His-SUMO (1)
His-T7 (1)
Myc-DDK (Flag) (2)
Human (4)
Mouse (1)
293T Cells (1)
E. coli (2)
HEK 293 Cells (1)
Wheat Germ Extract (2)
Purified (1)
SPTLC2 / LCB2 Antibody - Anti-SPTLC2 / LCB2 antibody IHC staining of human adrenal. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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SPTLC2 / LCB2 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, ICC, IF, IHC, IHC-P, WB
Unconjugated
50 µg/$460
SPTLC2 / LCB2 Antibody - Anti-SPTLC2 antibody IHC of human heart. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
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SPTLC2 / LCB2 Rabbit anti-Human Polyclonal (aa548-562) Antibody
Mouse, Sheep, Rat, Pig, Human
IHC, IHC-P, WB
Unconjugated
1 Each/$485
SPTLC2 / LCB2 Antibody - 1:100 staining human lymph carcinoma tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.
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SPTLC2 / LCB2 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
IF, IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
SPTLC2 / LCB2 Protein
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E. coli
His-SUMO
69.69 kD
1 mg/$1,355; 100 µg/$420; 20 µg/$323
SPTLC2 / LCB2 Protein - 12.5% SDS-PAGE of human SPTLC2 stained with Coomassie Blue
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Wheat Germ Extract
GST
89.3 kDa
2 µg/$439
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SPTLC2 / LCB2 Rabbit anti-Human Polyclonal (aa531-562) Antibody
Mouse, Human
ELISA, WB
Unconjugated
200 µl/$734
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SPTLC2 / LCB2 Rabbit anti-Human Polyclonal (aa531-562) (Biotin) Antibody
Mouse, Human
ELISA, WB
Biotin Conjugated
200 µl/$952
Select
SPTLC2 / LCB2 Rabbit anti-Human Polyclonal (aa531-562) (FITC) Antibody
Mouse, Human
ELISA, WB
FITC Conjugated
200 µl/$952
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SPTLC2 / LCB2 Rabbit anti-Human Polyclonal (aa531-562) (APC) Antibody
Mouse, Human
ELISA, WB
APC Conjugated
200 µl/$952
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SPTLC2 / LCB2 Rabbit anti-Human Polyclonal (aa531-562) (Azide-free) (HRP) Antibody
Mouse, Human
ELISA, WB
HRP Conjugated, Azide-free
200 µl/$952
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SPTLC2 / LCB2 Rabbit anti-Human Polyclonal (aa531-562) (PE) Antibody
Mouse, Human
ELISA, WB
PE Conjugated
200 µl/$952
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SPTLC2 / LCB2 Rabbit anti-Human Polyclonal (aa372-401) Antibody
Human
ELISA, WB
Unconjugated
200 µl/$734
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SPTLC2 / LCB2 Rabbit anti-Human Polyclonal (aa372-401) (Biotin) Antibody
Human
ELISA, WB
Biotin Conjugated
200 µl/$952
Select
SPTLC2 / LCB2 Rabbit anti-Human Polyclonal (aa372-401) (FITC) Antibody
Human
ELISA, WB
FITC Conjugated
200 µl/$952
Select
SPTLC2 / LCB2 Rabbit anti-Human Polyclonal (aa372-401) (APC) Antibody
Human
ELISA, WB
APC Conjugated
200 µl/$952
Select
SPTLC2 / LCB2 Rabbit anti-Human Polyclonal (aa372-401) (PE) Antibody
Human
ELISA, WB
PE Conjugated
200 µl/$952
Select
SPTLC2 / LCB2 Rabbit anti-Human Polyclonal (aa372-401) (Azide-free) (HRP) Antibody
Human
ELISA, WB
HRP Conjugated, Azide-free
200 µl/$952
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SPTLC2 / LCB2 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
100 µg/$351
SPTLC2 / LCB2 Antibody - Immunohistochemistry of paraffin-embedded human adrenal gland tissue using SPTLC2 Antibody at dilution of 1:100
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SPTLC2 / LCB2 Rabbit anti-Human Polyclonal (aa88-562) Antibody
Human
ELISA
Unconjugated
50 µg/$294; 100 µg/$360
SPTLC2 / LCB2 Antibody - Western blot of SPTLC2 / LCB2 antibody.
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SPTLC2 / LCB2 Rabbit anti-Mouse Polyclonal (aa453-560) Antibody
Mouse
WB
Unconjugated
100 µl/$311; 200 µl/$355; 500 µl/$499; 1 ml/$571; 2 ml/$777; 5 ml/$1,261
SPTLC2 / LCB2 Antibody - The anti-SPTLC2 antibody is used in Western blot to detect SPTLC2 in mouse liver tissue lysate.
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SPTLC2 / LCB2 Rabbit anti-Human Polyclonal (aa531-562) Antibody
Mouse, Human
WB
Unconjugated
400 µl/$393
SPTLC2 / LCB2 Antibody - SPTLC2 Antibody western blot of HepG2 cell line lysates (35 ug/lane). The SPTLC2 antibody detected the SPTLC2 protein (arrow).
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SPTLC2 / LCB2 Rabbit anti-Human Polyclonal (aa372-401) Antibody
Human
WB
Unconjugated
400 µl/$393
SPTLC2 / LCB2 Antibody - SPTLC2 antibody Western blot of HepG2 cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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SPTLC2 / LCB2 Rabbit anti-Human Polyclonal (aa72-121) Antibody
Human
WB
Unconjugated
100 µl/$424
SPTLC2 / LCB2 Antibody
Select
SPTLC2 / LCB2 Rabbit anti-Human Polyclonal Antibody
Human
WB
Unconjugated
50 µl/$286; 100 µl/$321
SPTLC2 / LCB2 Antibody - Western blot analysis of extracts of various cell lines, using SPTLC2 Antibody at 1:3000 dilution. The secondary antibody used was an HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates were loaded 25ug per lane and 3% nonfat dry milk in TBST was used for blocking. An ECL Kit was used for detection and the exposure time was 90s.
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SPTLC2 / LCB2 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
WB
Unconjugated
20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503
Viewing 1-25 of 44 product results



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The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).