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SPTLC1 / HSN1

serine palmitoyltransferase, long chain base subunit 1

Serine palmitoyltransferase (SPT). The heterodimer formed with SPTLC2 or SPTLC3 constitutes the catalytic core. The composition of the serine palmitoyltransferase (SPT) complex determines the substrate preference. The SPTLC1-SPTLC2-SPTSSA complex shows a strong preference for C16-CoA substrate, while the SPTLC1-SPTLC3-SPTSSA isozyme uses both C14-CoA and C16-CoA as substrates, with a slight preference for C14-CoA. The SPTLC1-SPTLC2-SPTSSB complex shows a strong preference for C18-CoA substrate, while the SPTLC1-SPTLC3-SPTSSB isozyme displays an ability to use a broader range of acyl-CoAs, without apparent preference.

Gene Name: serine palmitoyltransferase, long chain base subunit 1
Synonyms: SPTLC1, HSAN1, HLCB1, HSAN, LCB1, HSN1, LCB 1, Serine palmitoyltransferase 1, SPTI, SPT 1, Serine C-palmitoyltransferase, LBC1, SPT1
Target Sequences: NM_006415 NP_006406.1 O15269

☰ Filters
Antibodies (44)
Proteins (7)
ELISA Kits (1)
Over-Expression Lysate (4)
Primary (44)
Recombinant (3)
Sandwich (1)
SPTLC1 / HSN1 (52)
Human (44)
Mouse (25)
Rat (12)
Bat (4)
Bovine (5)
Chimpanzee (6)
Gibbon (6)
Guinea pig (6)
Hamster (6)
Horse (3)
Monkey (7)
Orangutan (6)
Pig (4)
Rabbit (7)
Sheep (1)
Zebrafish (3)
IHC (14)
IHC-P (9)
WB (44)
ELISA (15)
ICC (1)
IF (1)
IP (3)
Peptide-ELISA (1)
rabbit (44)
Product Group
IHCPlus (1)
IgG (30)
polyclonal pc (44)
96-Well Strip Plate (1)
APC (1)
APC Conjugated (3)
Azide-free (2)
Biotin Conjugated (5)
Cy3 Conjugated (1)
Cy7 Conjugated (1)
FITC Conjugated (5)
HRP Conjugated (5)
PE Conjugated (3)
Unconjugated (21)
aa143-473 (8)
aa26-57 (7)
aa405-437 (6)
aa216-265 (4)
aa254-303 (4)
411-460 aa, C-terminal (1)
C-Terminus (1)
aa138-154 (1)
aa37-310 (1)
aa423-473 (1)
aa444-473 (1)
aa50-100 (1)
No (52)
Tissue Homogenates (1)
GST (1)
His-T7 (1)
Myc-DDK (Flag) (5)
Human (4)
Mouse (1)
293T Cells (2)
E. coli (1)
HEK 293 Cells (3)
Wheat Germ Extract (1)
Purified (1)
SPTLC1 / HSN1 Antibody - SPTLC1 antibody SPTLC1(serine palmitoyltransferase, long chain base subunit 1) Antibody was used in IHC to stain formalin-fixed, paraffin-embedded human kidney.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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SPTLC1 / HSN1 Rabbit anti-Human Polyclonal (aa254-303) Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µl/$424
SPTLC1 / HSN1 Antibody - SPTLC1 antibody SPTLC1(serine palmitoyltransferase, long chain base subunit 1) Antibody was used in IHC to stain formalin-fixed, paraffin-embedded human kidney.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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SPTLC1 / HSN1 Rabbit anti-Human Polyclonal (aa254-303) (HRP) Antibody
Rabbit, Mouse, Guinea pig, Rat, Hamster, Chimpanzee, Orangutan, Gibbon, Human, Monkey
IHC, IHC-P, WB
HRP Conjugated
100 µl/$469
SPTLC1 / HSN1 Antibody - SPTLC1 antibody SPTLC1(serine palmitoyltransferase, long chain base subunit 1) Antibody was used in IHC to stain formalin-fixed, paraffin-embedded human kidney.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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SPTLC1 / HSN1 Rabbit anti-Human Polyclonal (aa254-303) (Biotin) Antibody
Rabbit, Mouse, Guinea pig, Rat, Hamster, Chimpanzee, Orangutan, Gibbon, Human, Monkey
IHC, IHC-P, WB
Biotin Conjugated
100 µl/$469
SPTLC1 / HSN1 Antibody - SPTLC1 antibody SPTLC1(serine palmitoyltransferase, long chain base subunit 1) Antibody was used in IHC to stain formalin-fixed, paraffin-embedded human kidney.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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SPTLC1 / HSN1 Rabbit anti-Human Polyclonal (aa254-303) (FITC) Antibody
Rabbit, Mouse, Guinea pig, Rat, Hamster, Chimpanzee, Orangutan, Gibbon, Human, Monkey
IHC, IHC-P, WB
FITC Conjugated
100 µl/$469
SPTLC1 / HSN1 Antibody - Human Heart: Formalin-Fixed, Paraffin-Embedded (FFPE)
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SPTLC1 / HSN1 Rabbit anti-Human Polyclonal (aa50-100) Antibody
Mouse, Human
IHC, IHC-P, IP, WB
Unconjugated
100 µl/$485
SPTLC1 / HSN1 Antibody - Western blot of hSPTLC1-S41 in 293, HeLa, K562 cell line and mouse liver tissue lysates (35 ug/lane). SPTLC1 (arrow) was detected using the purified antibody.
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SPTLC1 / HSN1 Rabbit anti-Human Polyclonal (aa26-57) Antibody
Mouse, Human
WB
Unconjugated
400 µl/$393
SPTLC1 / HSN1 Antibody - Immunohistochemistry of paraffin-embedded human colorectal carcinoma using antibody at 1:100 dilution.
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SPTLC1 / HSN1 Rabbit anti-Human Polyclonal (aa37-310) Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µl/$294; 100 µl/$360
SPTLC1 / HSN1 Protein - 12.5% SDS-PAGE of human SPTLC1 stained with Coomassie Blue
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Wheat Germ Extract
GST
36.85 kDa
10 µg/$479; 25 µg/$670
SPTLC1 / HSN1 Antibody - Western blot of SPTLC1 / HSN1 antibody.
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SPTLC1 / HSN1 Rabbit anti-Mouse Polyclonal (aa143-473) Antibody
Mouse, Human
ICC, IP, WB
Unconjugated
100 µl/$311; 200 µl/$355; 500 µl/$499; 1 ml/$571; 2 ml/$777; 5 ml/$1,261
SPTLC1 / HSN1 Antibody - SPTLC1 / HSN1 antibody. IHC(P): Human Breast Cancer Tissue.
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SPTLC1 / HSN1 Rabbit anti-Human Polyclonal (aa138-154) Antibody
Rabbit, Sheep, Bovine, Pig, Bat, Human, Monkey
IHC, IHC-P, WB
Unconjugated
10 µg/$318; 100 µg/$470
Select
SPTLC1 / HSN1 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, WB
Unconjugated
100 µg/$341
SPTLC1 / HSN1 Antibody - SPTLC1 was detected in paraffin-embedded sections of human intestinal cancer tissues using rabbit anti- SPTLC1 Antigen Affinity purified polyclonal antibody at 1 ug/mL. The immunohistochemical section was developed using SABC method.
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SPTLC1 / HSN1 Rabbit anti-Human Polyclonal (aa444-473) Antibody
Mouse, Rat, Human
IHC, IHC-P, WB
Unconjugated
10 µg/$318; 100 µg/$470
SPTLC1 / HSN1 Antibody - Immunohistochemistry of SPT1 in human lung tissue with SPT1 antibody at 5 ug/ml.
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SPTLC1 / HSN1 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, WB
Unconjugated
0.1 mg/$460
SPTLC1 / HSN1 Antibody - Western blot analysis of extracts of HepG2 cells using SPTLC1 antibody. The lane on the left was treated with blocking peptide.
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SPTLC1 / HSN1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
SPTLC1 / HSN1 Antibody
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SPTLC1 / HSN1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, IHC-P, WB
Unconjugated
100 µg/$575
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SPTLC1 / HSN1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, WB
Unconjugated
60 µl/$331; 120 µl/$403; 200 µl/$529
SPTLC1 / HSN1 Antibody - Left: IHC of normal human lung tissue with serine palmitoyltransferase 1 antibody at 15 ug/ml. Right: Western blot on human kidney lysate (10 ug/lane) using anti Serine palmitoyltransferase 1 antibody at 1 ug/ml. Blot was developed using anti rabbit HRP at 1:75k and Pierce Supersignal West Femto. Exposure was 2 minutes.
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SPTLC1 / HSN1 Rabbit anti-Human Polyclonal Antibody
Human
IHC, WB
Unconjugated
100 µg/$466
SPTLC1 / HSN1 Antibody - Immunohistochemistry of paraffin-embedded human liver injury tissue.
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SPTLC1 / HSN1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, WB
Unconjugated
20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503
Select
SPTLC1 / HSN1 Rabbit anti-Human Polyclonal (aa26-57) Antibody
Mouse, Human
ELISA, WB
Unconjugated
200 µl/$734
SPTLC1 / HSN1 Antibody - Western blot of SPTLC1 antibody
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SPTLC1 / HSN1 Rabbit anti-Human Polyclonal (411-460 aa, C-terminal) Antibody
Mouse, Rat, Human
ELISA, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
Select
SPTLC1 / HSN1 Rabbit anti-Human Polyclonal (aa423-473) Antibody
Human
IP, WB
Unconjugated
10 µl/$295; 100 µl/$514
Select
SPTLC1 / HSN1 Rabbit anti-Human Polyclonal (aa405-437) (Biotin) Antibody
Human
ELISA, WB
Biotin Conjugated
200 µl/$952
Select
SPTLC1 / HSN1 Rabbit anti-Human Polyclonal (aa405-437) (APC) Antibody
Human
ELISA, WB
APC Conjugated
200 µl/$952
Select
SPTLC1 / HSN1 Rabbit anti-Human Polyclonal (aa405-437) (FITC) Antibody
Human
ELISA, WB
FITC Conjugated
200 µl/$952
Select
SPTLC1 / HSN1 Rabbit anti-Human Polyclonal (aa405-437) (Azide-free) (HRP) Antibody
Human
ELISA, WB
HRP Conjugated, Azide-free
200 µl/$952
Viewing 1-25 of 52 product results



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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).