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SPTBN2

spectrin, beta, non-erythrocytic 2

Spectrins are principle components of a cell's membrane-cytoskeleton and are composed of two alpha and two beta spectrin subunits. The protein encoded by this gene (SPTBN2), is called spectrin beta non-erythrocytic 2 or beta-III spectrin. It is related to, but distinct from, the beta-II spectrin gene which is also known as spectrin beta non-erythrocytic 1 (SPTBN1). SPTBN2 regulates the glutamate signaling pathway by stabilizing the glutamate transporter EAAT4 at the surface of the plasma membrane. Mutations in this gene cause a form of spinocerebellar ataxia, SCA5, that is characterized by neurodegeneration, progressive locomotor incoordination, dysarthria, and uncoordinated eye movements.

Gene Name: spectrin, beta, non-erythrocytic 2
Synonyms: SPTBN2, Beta-III spectrin, GTRAP41, SCA5, Spectrin beta chain, brain 2, Spinocerebellar ataxia 5, KIAA0302
Target Sequences: NM_006946 NP_008877.1 O15020

☰ Filters
Antibodies (22)
Proteins (3)
Over-Expression Lysate (2)
Primary (22)
Recombinant (1)
SPTBN2 (25)
Human (22)
Mouse (1)
IHC (9)
IHC-P (14)
WB (19)
Flo (9)
ELISA (6)
IF (6)
IP (10)
rabbit (14)
mouse (8)
Product Group
IHCPlus (1)
IgG (6)
IgG1 (2)
IgG2a,k (3)
IgG2b,k (2)
IgG3,k (1)
monoclonal mc (8)
polyclonal pc (12)
recombinant monoclonal rmc (2)
4D9 (1)
SPTBN2/1582 (2)
SPTBN2/1583 (2)
SPTBN2/1584 (2)
SPTBN2/2894R (2)
Azide-free (4)
Biotin Conjugated (1)
BSA-free (3)
Carrier-free (1)
DY488 Conjugated (1)
DY550 Conjugated (1)
DY650 Conjugated (1)
Unconjugated (18)
aa2300-2390 (5)
aa2150-2200 (3)
aa356-475 (2)
C-Terminus (1)
Met687 (1)
aa2340-2390 (1)
No (25)
GST, N-terminus (1)
Myc-DDK (Flag) (2)
Human (3)
293T Cells (1)
HEK 293 Cells (1)
Wheat Germ Extract (1)
SPTBN2 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
271.1 kDa
100 µg/$710
SPTBN2 Antibody - Detection of Spectrin Beta III in human prostate epithelium.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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SPTBN2 Rabbit anti-Human Polyclonal (aa2300-2390) Antibody
Human
IHC, IHC-P, IP, WB
Unconjugated
0.1 ml/$386
SPTBN2 Antibody - Detection of Spectrin Beta III in human prostate epithelium.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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SPTBN2 Rabbit anti-Human Polyclonal (aa2300-2390) (Biotin) Antibody
Human
IHC, IHC-P, IP, WB
Biotin Conjugated
0.1 ml/$416
SPTBN2 Antibody - Detection of Spectrin Beta III in human prostate epithelium.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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SPTBN2 Rabbit anti-Human Polyclonal (aa2300-2390) (DY650) Antibody
Human
IHC, IHC-P, IP, WB
DY650 Conjugated
0.1 ml/$416
SPTBN2 Antibody - Detection of Spectrin Beta III in human prostate epithelium.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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SPTBN2 Rabbit anti-Human Polyclonal (aa2300-2390) (DY488) Antibody
Human
IHC, IHC-P, IP, WB
DY488 Conjugated
0.1 ml/$416
SPTBN2 Antibody - Detection of Spectrin Beta III in human prostate epithelium.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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SPTBN2 Rabbit anti-Human Polyclonal (aa2300-2390) (DY550) Antibody
Human
IHC, IHC-P, IP, WB
DY550 Conjugated
0.1 ml/$416
SPTBN2 Antibody - Human Brain, Cerebellum: Formalin-Fixed, Paraffin-Embedded (FFPE)
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SPTBN2 Rabbit anti-Human Polyclonal (aa2340-2390) Antibody
Human
IHC, IHC-P, IP, WB
Unconjugated
50 µl/$460
SPTBN2 Antibody - IHC testing of FFPE human pancreas with Spectrin beta III antibody (clone SPTBN2/1582). Required HIER: boil tissue sections in 10mM citrate buffer, pH 6, for 10-20 min followed by cooling at RT for 20 min.
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SPTBN2 Mouse anti-Human Monoclonal (SPTBN2/1582) Antibody
Human
ELISA, Flo, IF, IHC-P, WB
Unconjugated
20 µg/$371; 100 µg/$574
SPTBN2 Antibody - IHC testing of FFPE human pancreas with Spectrin beta III antibody (clone SPTBN2/1582). Required HIER: boil tissue sections in 10mM citrate buffer, pH 6, for 10-20 min followed by cooling at RT for 20 min.
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SPTBN2 Mouse anti-Human Monoclonal (Azide-free, BSA-free) (SPTBN2/1582) Antibody
Human
ELISA, Flo, IF, IHC-P, WB
Unconjugated, Azide-free, BSA-free
100 µg/$574
SPTBN2 Antibody - IHC testing of FFPE human pancreas with Spectrin beta III antibody (clone SPTBN2/1584). Required HIER: boil tissue sections in 10mM citrate buffer, pH 6, for 10-20 min followed by cooling at RT for 20 min.
Select
SPTBN2 Mouse anti-Human Monoclonal (SPTBN2/1584) Antibody
Human
Flo, IF, IHC-P, WB
Unconjugated
20 µg/$371; 100 µg/$574
SPTBN2 Antibody - IHC testing of FFPE human pancreas with Spectrin beta III antibody (clone SPTBN2/1584). Required HIER: boil tissue sections in 10mM citrate buffer, pH 6, for 10-20 min followed by cooling at RT for 20 min.
Select
SPTBN2 Mouse anti-Human Monoclonal (Azide-free, BSA-free) (SPTBN2/1584) Antibody
Human
Flo, IF, IHC-P, WB
Unconjugated, Azide-free, BSA-free
100 µg/$574
SPTBN2 Antibody - IHC testing of FFPE human pancreas with Spectrin beta III antibody (clone SPTBN2/1583). Required HIER: boil tissue sections in 10mM citrate buffer, pH 6, for 10-20 min followed by cooling at RT for 20 min.
Select
SPTBN2 Mouse anti-Human Monoclonal (SPTBN2/1583) Antibody
Human
Flo, IF, IHC-P, WB
Unconjugated
20 µg/$371; 100 µg/$574
SPTBN2 Antibody - IHC testing of FFPE human pancreas with Spectrin beta III antibody (clone SPTBN2/1583). Required HIER: boil tissue sections in 10mM citrate buffer, pH 6, for 10-20 min followed by cooling at RT for 20 min.
Select
SPTBN2 Mouse anti-Human Monoclonal (Azide-free, BSA-free) (SPTBN2/1583) Antibody
Human
Flo, IF, IHC-P, WB
Unconjugated, Azide-free, BSA-free
100 µg/$574
SPTBN2 Antibody - Formalin-fixed, paraffin-embedded human Pancreatic Cancer stained with Spectrin beta III Rabbit Recombinant Monoclonal (SPTBN2/2894R).
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SPTBN2 Rabbit anti-Human Recombinant Monoclonal (aa356-475) (SPTBN2/2894R) Antibody
Human
ELISA, Flo, IHC-P, WB
Unconjugated
20 µg/$371; 100 µg/$574
SPTBN2 Antibody - Formalin-fixed, paraffin-embedded human Pancreatic Cancer stained with Spectrin beta III Rabbit Recombinant Monoclonal (SPTBN2/2894R).
Select
SPTBN2 Rabbit anti-Human Recombinant Monoclonal (aa356-475) (Azide-free, Carrier-free) (SPTBN2/2894R) Antibody
Human
ELISA, Flo, IHC-P, WB
Unconjugated, Azide-free, Carrier-free
100 µg/$574
SPTBN2 Antibody - Fig-1: Western blot analysis of Spectrin beta 3. Anti-Spectrin beta 3 antibody was used at 0.1 µg/ml on h Kidney and h Brain lysates.
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SPTBN2 Mouse anti-Human Monoclonal Antibody
Human
Flo, WB
Unconjugated
25 µg/$288; 100 µg/$414
Select
SPTBN2 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Human
IHC, IP, WB
Unconjugated
100 µl/$649
SPTBN2 Antibody - Detection limit for recombinant GST tagged SPTBN2 is approximately 0.1 ng/ml as a capture antibody.
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SPTBN2 Mouse anti-Human Monoclonal (4D9) Antibody
Human
ELISA, WB
Unconjugated
100 µg/$423
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SPTBN2 Rabbit anti-Human Polyclonal (aa2150-2200) Antibody
Human
IHC, IP
Unconjugated
100 µl/$640
Select
SPTBN2 Rabbit anti-Human Polyclonal (aa2150-2200) Antibody
Human
IHC, IP
Unconjugated
100 µl/$755
Select
SPTBN2 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
100 µg/$341
SPTBN2 Antibody - Western blot of Spectrin II (M687) pAb in extracts from COLO cells.
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SPTBN2 Rabbit anti-Human Polyclonal (Met687) Antibody
Mouse, Human
WB
Unconjugated
50 µl/$321; 100 µl/$403
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SPTBN2 Rabbit anti-Human Polyclonal (aa2150-2200) Antibody
Human
IP
Unconjugated
10 µg/$295; 100 µl/$514
SPTBN2 Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
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Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
SPTBN2 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
271.1 kDa
20 µg/$215
Viewing 1-25 of 25 product results



If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).