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SPTAN1 / Alpha Fodrin
spectrin, alpha, non-erythrocytic 1
Spectrins are a family of filamentous cytoskeletal proteins that function as essential scaffold proteins that stabilize the plasma membrane and organize intracellular organelles. Spectrins are composed of alpha and beta dimers that associate to form tetramers linked in a head-to-head arrangement. This gene encodes an alpha spectrin that is specifically expressed in nonerythrocytic cells. The encoded protein has been implicated in other cellular functions including DNA repair and cell cycle regulation. Mutations in this gene are the cause of early infantile epileptic encephalopathy-5. Alternate splicing results in multiple transcript variants.
| Gene Name: | spectrin, alpha, non-erythrocytic 1 |
| Synonyms: | SPTAN1, Alpha-II spectrin, Alpha Fodrin, Fodrin alpha chain, EIEE5, NEAS, Alpha-fodrin, Spectrin alpha chain, brain, SPTA2 |
| Target Sequences: | NM_003127 NP_003118.2 Q13813 |
Publications (2)
1
Polarization of membrane associated proteins in the choroid plexus epithelium from normal and slc4a10 knockout mice. Christensen IB, Gyldenholm T, Damkier HH, Praetorius J. Frontiers in physiology. 2013 4:344. (IHC; Mouse)
[Full Text Article]
[PubMed:24348423]
[PMC:PMC3842056]
2
Genetic disruption of slc4a10 alters the capacity for cellular metabolism and vectorial ion transport in the choroid plexus epithelium. Christensen IB, Wu Q, Bohlbro AS, Skals MG, Damkier HH, Hübner CA, Fenton RA, Praetorius J. Fluids and barriers of the CNS. 2020 January;17:2. [Full Text Article]
[PubMed:31906971]
[PMC:PMC6945596]
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(15)
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(1)
SPTAN1 / Alpha Fodrin Rabbit anti-Human Polyclonal Antibody
Mouse, Human
ICC, IF, IHC, IHC-P, WB
Unconjugated
50 µl/$460
Sandwich
96-Well Strip Plate
Rat
0.312 - 20 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$783
E. coli
His, N-Terminal
20.4 kDa
10 µg/$255; 50 µg/$323; 100 µg/$450; 200 µg/$562; 1 mg/$1,480; 500 µg/$1,096; 5 mg/$2,395; 2 mg/$1,646
SPTAN1 / Alpha Fodrin Mouse anti-Human Monoclonal (3D7) Antibody
Human
ICC, IF, WB
Unconjugated
100 µl/$376
SPTAN1 / Alpha Fodrin Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Mouse, Human
IHC, IHC-P, WB
Unconjugated
100 µl/$485
SPTAN1 / Alpha Fodrin Rabbit anti-Human Polyclonal (N-Terminus) (HRP) Antibody
Xenopus, Chicken, Bovine, Rabbit, Mouse, Rat, Bat, Pig, Horse, Gibbon, Chimpanzee, Human, Monkey
IHC, IHC-P, WB
HRP Conjugated
100 µl/$469
SPTAN1 / Alpha Fodrin Rabbit anti-Human Polyclonal (N-Terminus) (Biotin) Antibody
Xenopus, Chicken, Bovine, Rabbit, Mouse, Rat, Bat, Pig, Horse, Gibbon, Chimpanzee, Human, Monkey
IHC, IHC-P, WB
Biotin Conjugated
100 µl/$469
SPTAN1 / Alpha Fodrin Rabbit anti-Human Polyclonal Antibody
Human
ICC, IHC, WB
Unconjugated
100 µl/$671
SPTAN1 / Alpha Fodrin Rabbit anti-Human Polyclonal (Internal) Antibody
Human
IP, WB
Unconjugated
30 µl/$255; 100 µl/$299; 200 µl/$351
SPTAN1 / Alpha Fodrin Mouse anti-Human Monoclonal Antibody
Chicken, Rabbit, Guinea pig, Rat, Human
IF, IHC, IHC-P, WB
Unconjugated
50 µg/$995
SPTAN1 / Alpha Fodrin Rabbit anti-Human Polyclonal (aa2422-2472) Antibody
Mouse, Human
IF, IHC, WB
Unconjugated
10 µl/$295; 100 µl/$514
SPTAN1 / Alpha Fodrin Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC-P, WB
Unconjugated
60 µl/$460
SPTAN1 / Alpha Fodrin Mouse anti-Chicken Monoclonal (AA6) Antibody
Chicken, Rabbit, Guinea pig, Rat, Human
ELISA, IHC, IHC-Fr, WB
Unconjugated
100 µg/$995
Sandwich CLIA
12 x 8-Well Microstrips
Human
31.25 - 2000 pg/ml
Chemiluminescent
Plasma, Serum
1 Plate/$728
SPTAN1 / Alpha Fodrin Mouse anti-Human Monoclonal (aa1-147) (OTI9C10) Antibody
Human
IHC, WB
Unconjugated
100 µl/$434
SPTAN1 / Alpha Fodrin Rabbit anti-Human Polyclonal (aa2422-2472) Antibody
Human
IF, IHC
Unconjugated
2.5 µg/$295; 100 µl/$532
SPTAN1 / Alpha Fodrin Mouse anti-Bovine Monoclonal (3D7) Antibody
Mouse, Bovine, Rat, Human
IF, IHC, WB
Unconjugated
100 µl/$469
SPTAN1 / Alpha Fodrin Mouse anti-Human Monoclonal (Concentrated) (AA6) Antibody
Human
IHC, IHC-Fr, WB
Unconjugated, Concentrated
1 ml/$669
SPTAN1 / Alpha Fodrin Rabbit anti-Human Polyclonal Antibody
Human
IF, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
SPTAN1 / Alpha Fodrin Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, WB
Unconjugated
100 µl/$436
SPTAN1 / Alpha Fodrin Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IHC
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
SPTAN1 / Alpha Fodrin Rabbit anti-Human Polyclonal (aa1000-1050) Antibody
Mouse, Human
IHC, WB
Unconjugated
10 µl/$295; 100 µl/$514
SPTAN1 / Alpha Fodrin Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Human
ELISA, WB
Unconjugated
100 µl/$689
SPTAN1 / Alpha Fodrin Rabbit anti-Human Polyclonal (Asp1185) Antibody
Human
ELISA, WB
Unconjugated
100 µl/$688
SPTAN1 / Alpha Fodrin Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Human
ELISA, WB
Unconjugated
100 µg/$832
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