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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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SPR Antibody (clone 2F7) LS‑C115799
SPR antibody LS-C115799 is an unconjugated mouse monoclonal antibody to SPR from human and monkey. Validated for WB.
Catalog
Size
Price
LS-C115799-100
100 µl
Unavailable

Popular SPR Products

Anti-SPR mouse monoclonal antibody  immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY SPR.
Species: Human, Monkey
Applications: Immunofluorescence, Western blot, Flow Cytometry
IHC of paraffin-embedded Carcinoma of Human pancreas tissue using anti-SPR mouse monoclonal antibody.
Species: Human, Monkey
Applications: IHC, IHC - Paraffin, Western blot, Flow Cytometry
IHC of paraffin-embedded Carcinoma of Human prostate tissue using anti-SPR mouse monoclonal antibody.
Species: Human, Rat
Applications: IHC, IHC - Paraffin, Immunofluorescence, Western blot, Flow Cytometry
Western Blot analysis of SPR expression in transfected 293T cell line by SPR monoclonal antibody (M01), clone 4F2.Lane 1: SPR transfected lysate(28 KDa).Lane 2: Non-transfected lysate.
Species: Human
Applications: Western blot, Immunoprecipitation, ELISA
Antibody
Species: Human, Mouse
Applications: Western blot, ELISA

Product Description

SPR antibody LS-C115799 is an unconjugated mouse monoclonal antibody to SPR from human and monkey. Validated for WB.
About SPR
SPR is an aldo-keto reductase that catalyzes the NADPH-dependent reduction of pteridine derivatives and is important in the biosynthesis of tetrahydrobiopterin (BH4). Mutations in this gene result in DOPA-responsive dystonia due to sepiaterin reductase deficiency. A pseudogene has been identified on chromosome 1. P35270 NM_003124 NP_003115.1

SPR Antibody, SDR38C1 Antibody, Sepiapterin reductase Antibody


Specifications

Target
Human SPR
Host
Mouse
Reactivity
Human, Monkey (tested or 100% immunogen sequence identity)
Clonality
IgG1 Monoclonal [2F7]
Conjugations
Unconjugated
Purification
Protein A/G purified
Modifications
Unmodified
Applications
  • Western blot (1:500 - 1:2000)
Immunogen
SPR antibody was raised against full length human recombinant protein of human SPR (NP_003115) produced in HEK293T cell.
Specificity
Human SPR
Usage
Concentration: 0.45 mg/ml (Lot dependent)
Presentation
PBS, pH 7.3, 1% BSA, 50% glycerol, 0.02% sodium azide
Storage
Store at -20°C. Avoid freeze-thaw cycles.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Images


Western blot

Western blot of extracts (35 ug) from 9 different cell lines by using anti-SPR monoclonal antibody.
Western blot of extracts (35 ug) from 9 different cell lines by using anti-SPR monoclonal antibody.

Western blot

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY SPR (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-SPR.
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY SPR (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-SPR.

Western blot

Western blot of extracts (35 ug) from 9 different cell lines by using anti-SPR monoclonal antibody.
Western blot of extracts (35 ug) from 9 different cell lines by using anti-SPR monoclonal antibody.

Western blot

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY SPR (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-SPR.
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY SPR (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-SPR.

Western blot

Western blot of extracts (35 ug) from 9 different cell lines by using anti-SPR monoclonal antibody.
Western blot of extracts (35 ug) from 9 different cell lines by using anti-SPR monoclonal antibody.

Western blot

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY SPR (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-SPR.
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY SPR (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-SPR.

Western blot

Western blot of extracts (35 ug) from 9 different cell lines by using anti-SPR monoclonal antibody.
Western blot of extracts (35 ug) from 9 different cell lines by using anti-SPR monoclonal antibody.

Western blot

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY SPR (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-SPR.
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY SPR (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-SPR.


Requested From: 
Date Requested: 6/24/2018

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