Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Mouse Monoclonal [clone DF-T1] (IgG1,k) to Human SPN / CD43
IHC - Paraffin, Immunofluorescence, Western blot, Immunoprecipitation, Flow Cytometry, ELISA
Mouse Monoclonal [clone W3/13 HLK] (IgG1) to Rat SPN / CD43
Rat SPN / CD43
Rat (tested or 100% immunogen sequence identity)
IgG1 Monoclonal [W3/13 HLK]
Protein G purified
Flow Cytometry (1 µg/10E6 cells)
Specificity and Use
SPN / CD43 antibody was raised against rat thymocyte membrane.
Anti-rat CD43 monoclonal antibody recognizes a monomorphic determinant expressed on rat thymocytes, polymorphonuclear cells, plasma cells and stem cells, but not B lymphocytes or pre-B cells. The antigen is a heavily glycosylated glycoprotein of apparent
The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.
One of the major glycoproteins of thymocytes and T lymphocytes. Plays a role in the physicochemical properties of the T-cell surface and in lectin binding. Presents carbohydrate ligands to selectins. Has an extended rodlike structure that could protrude above the glycocalyx of the cell and allow multiple glycan chains to be accessible for binding. Is a counter-receptor for SN/Siglec-1 (By similarity).