SPIN / SPIN1

spindlin 1

Chromatin reader that specifically recognizes and binds histone H3 both trimethylated at 'Lys-4' and asymmetrically dimethylated at 'Arg-8' (H3K4me3 and H3R8me2a) and acts as an activator of Wnt signaling pathway dowstream of PRMT2. In case of cancer, promotes cell cancer proliferation via activation of the Wnt signaling pathway (PubMed:24589551). Overexpression induces metaphase arrest and chromosomal instability. Localizes to active rDNA loci and promotes the expression of rRNA genes (PubMed:21960006). May play a role in cell-cycle regulation during the transition from gamete to embryo. Involved in oocyte meiotic resumption, a process that takes place before ovulation to resume meiosis of oocytes blocked in prophase I: may act by regulating maternal transcripts to control meiotic resumption.

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Products

Antibodies (28)

Proteins (7)

Type

Over-Expression Lysate (2)

Primary (28)

Recombinant (5)

Target

SPIN / SPIN1 (35)

Reactivity

Human (28)

Mouse (15)

Rat (15)

Bat (3)

Bovine (6)

Chicken (4)

Chimpanzee (3)

Dog (6)

Gibbon (3)

Guinea pig (3)

Monkey (4)

Orangutan (3)

Pig (7)

Rabbit (6)

Xenopus (3)

Zebrafish (3)

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Application

IHC (13)

IHC-P (7)

WB (28)

ELISA (5)

ICC (1)

IF (7)

IP (1)

Peptide-ELISA (3)

Host

rabbit (28)

Product Group

IHCPlus (2)

Isotype

IgG (10)

Clonality

polyclonal pc (28)

Format

APC (1)

APC Conjugated (1)

Biotin Conjugated (3)

Cy3 Conjugated (1)

Cy7 Conjugated (1)

FITC Conjugated (3)

HRP Conjugated (3)

PE Conjugated (1)

Unconjugated (15)

Epitope

aa1-262 (8)

N-Terminus (4)

aa179-228 (4)

80-160 aa, Internal (1)

His139 (1)

Internal (1)

aa111-160 (1)

aa90-139 (1)

Publications

No (35)

Tag

GST (1)

GST, N-terminus (1)

His (1)

His-T7 (1)

Myc-DDK (Flag) (3)

Species

Human (6)

Source

293T Cells (1)

E. coli (3)

HEK 293 Cells (2)

Wheat Germ Extract (1)

Purification

Purified (3)

Select

SPIN / SPIN1 Antibody (Internal) LS-C358866

Antibody:

SPIN / SPIN1 Rabbit anti-Human Polyclonal (Internal) Antibody

Reactivity:

Chicken, Rat, Pig, Mouse, Human, Monkey

Applications:

ICC, IF, IHC, IHC-P, WB

Format:

Unconjugated

Price:

30 µl/$255; 100 µl/$299; 200 µl/$351

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IHC-plus™ SPIN / SPIN1 Antibody (aa111-160) LS-B10006

(4.0) Rating

Antibody:

SPIN / SPIN1 Rabbit anti-Human Polyclonal (aa111-160) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC, IHC-P, Peptide-ELISA, WB

Format:

Unconjugated

Price:

50 µl/$460

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SPIN / SPIN1 Antibody LS-C334339

Antibody:

SPIN / SPIN1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IF, IHC, IP, WB

Format:

Unconjugated

Price:

20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503

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SPIN / SPIN1 Antibody LS-C755139

Antibody:

SPIN / SPIN1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IF, IHC, WB

Format:

Unconjugated

Price:

100 µg/$351

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SPIN / SPIN1 Antibody LS-C755289

Antibody:

SPIN / SPIN1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IF, IHC, WB

Format:

Unconjugated

Price:

100 µg/$341

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SPIN / SPIN1 Antibody (80-160 aa, Internal) LS-C386147

Antibody:

SPIN / SPIN1 Rabbit anti-Human Polyclonal (80-160 aa, Internal) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, IF, IHC, WB

Format:

Unconjugated

Price:

50 µg/$295; 100 µg/$335; 200 µg/$394

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SPIN / SPIN1 Antibody (aa179-228) LS-B12638

Antibody:

SPIN / SPIN1 Rabbit anti-Human Polyclonal (aa179-228) Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

100 µl/$485

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SPIN / SPIN1 Antibody (aa179-228, HRP) LS-C455760

Antibody:

SPIN / SPIN1 Rabbit anti-Human Polyclonal (aa179-228) (HRP) Antibody

Reactivity:

Xenopus, Chicken, Zebrafish, Rat, Pig, Bat, Bovine, Rabbit, Mouse, Dog, Guinea pig, Human, Monkey, Gibbon, Orangutan, Chimpanzee

Applications:

IHC, IHC-P, WB

Format:

HRP Conjugated

Price:

100 µl/$469

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SPIN / SPIN1 Antibody (aa179-228, Biotin) LS-C455758

Antibody:

SPIN / SPIN1 Rabbit anti-Human Polyclonal (aa179-228) (Biotin) Antibody

Reactivity:

Xenopus, Chicken, Zebrafish, Rat, Pig, Bat, Bovine, Rabbit, Mouse, Dog, Guinea pig, Human, Monkey, Gibbon, Orangutan, Chimpanzee

Applications:

IHC, IHC-P, WB

Format:

Biotin Conjugated

Price:

100 µl/$469

Select

SPIN / SPIN1 Antibody (aa179-228, FITC) LS-C455759

Antibody:

SPIN / SPIN1 Rabbit anti-Human Polyclonal (aa179-228) (FITC) Antibody

Reactivity:

Xenopus, Chicken, Zebrafish, Rat, Pig, Bat, Bovine, Rabbit, Mouse, Dog, Guinea pig, Human, Monkey, Gibbon, Orangutan, Chimpanzee

Applications:

IHC, IHC-P, WB

Format:

FITC Conjugated

Price:

100 µl/$469

• Unconjugated
• HRP
• Biotin
• FITC

• Unconjugated
• HRP
• Biotin
• More...
  • FITC

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SPIN / SPIN1 Antibody LS-C676541

Antibody:

SPIN / SPIN1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µl/$294; 100 µl/$360

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SPIN / SPIN1 Antibody LS-C770843

Antibody:

SPIN / SPIN1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IF, IHC, WB

Format:

Unconjugated

Price:

60 µl/$331; 120 µl/$403; 200 µl/$529

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SPIN / SPIN1 Antibody LS-C804608

Antibody:

SPIN / SPIN1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IF, Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µl/$379; 200 µl/$421

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SPIN / SPIN1 Antibody (His139) LS-C192056

Antibody:

SPIN / SPIN1 Rabbit anti-Human Polyclonal (His139) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC, WB

Format:

Unconjugated

Price:

50 µl/$321; 100 µl/$403

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SPIN / SPIN1 Antibody LS-C823335

Antibody:

SPIN / SPIN1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

100 µg/$357

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SPIN / SPIN1 Antibody (aa90-139) LS-C200717

Antibody:

SPIN / SPIN1 Rabbit anti-Human Polyclonal (aa90-139) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

Peptide-ELISA, WB

Format:

Unconjugated

Price:

50 µl/$334; 100 µl/$397

Select

SPIN / SPIN1 Antibody (N-Terminus) LS-C345498

Antibody:

SPIN / SPIN1 Rabbit anti-Human Polyclonal (N-Terminus) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$424

Select

SPIN / SPIN1 Antibody (N-Terminus, Biotin) LS-C455755

Antibody:

SPIN / SPIN1 Rabbit anti-Human Polyclonal (N-Terminus) (Biotin) Antibody

Reactivity:

Rabbit, Mouse, Dog, Bovine, Rat, Pig, Human

Applications:

WB

Format:

Biotin Conjugated

Price:

100 µl/$469

Select

SPIN / SPIN1 Antibody (N-Terminus, FITC) LS-C455756

Antibody:

SPIN / SPIN1 Rabbit anti-Human Polyclonal (N-Terminus) (FITC) Antibody

Reactivity:

Rabbit, Mouse, Dog, Bovine, Rat, Pig, Human

Applications:

WB

Format:

FITC Conjugated

Price:

100 µl/$469

• Unconjugated
• Biotin
• FITC

• Unconjugated
• Biotin
• FITC

Select

SPIN / SPIN1 Antibody (aa1-262) LS-C374686

Antibody:

SPIN / SPIN1 Rabbit anti-Human Polyclonal (aa1-262) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$309; 200 µl/$351; 500 µl/$491; 1 ml/$561; 2 ml/$755; 5 ml/$1,225

Select

SPIN / SPIN1 Antibody (aa1-262, Biotin) LS-C687522

Antibody:

SPIN / SPIN1 Rabbit anti-Human Polyclonal (aa1-262) (Biotin) Antibody

Reactivity:

Human

Applications:

WB

Format:

Biotin Conjugated

Price:

100 µl/$319; 200 µl/$365; 500 µl/$519; 1 ml/$596; 2 ml/$824; 5 ml/$1,348

Select

SPIN / SPIN1 Antibody (aa1-262, FITC) LS-C694352

Antibody:

SPIN / SPIN1 Rabbit anti-Human Polyclonal (aa1-262) (FITC) Antibody

Reactivity:

Human

Applications:

WB

Format:

FITC Conjugated

Price:

100 µl/$348; 200 µl/$407; 500 µl/$605; 1 ml/$755; 2 ml/$993; 5 ml/$1,716

Select

SPIN / SPIN1 Antibody (aa1-262, Cy3) LS-C702971

Antibody:

SPIN / SPIN1 Rabbit anti-Human Polyclonal (aa1-262) (Cy3) Antibody

Reactivity:

Human

Applications:

WB

Format:

Cy3 Conjugated

Price:

100 µl/$407; 200 µl/$491; 500 µl/$850; 1 ml/$1,008; 2 ml/$1,308; 5 ml/$2,451

Select

SPIN / SPIN1 Antibody (aa1-262, APC) LS-C740787

Antibody:

SPIN / SPIN1 Rabbit anti-Human Polyclonal (aa1-262) (APC) Antibody

Reactivity:

Human

Applications:

WB

Format:

APC Conjugated

Price:

100 µl/$407; 200 µl/$491; 500 µl/$850; 1 ml/$1,008; 2 ml/$1,308; 5 ml/$2,451

Select

SPIN / SPIN1 Antibody (aa1-262, APC, Cy7) LS-C735003

Antibody:

SPIN / SPIN1 Rabbit anti-Human Polyclonal (aa1-262) (APC, Cy7) Antibody

Reactivity:

Human

Applications:

WB

Format:

APC, Cy7 Conjugated

Price:

100 µl/$505; 200 µl/$648; 500 µl/$1,152; 1 ml/$1,401; 2 ml/$1,961; 5 ml/$3,676

• Unconjugated
• Biotin
• FITC
• Cy3
• APC
• APC, Cy7

• Unconjugated
• Biotin
• FITC
• More...
  • Cy3
  • APC
  • APC, Cy7

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