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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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SPHK / SPHK1 Antibody LS‑C152974
Antibody
SPHK1 antibody LS-C152974 is an unconjugated rabbit polyclonal antibody to human SPHK1 (SPHK). Validated for IHC.
Catalog
Size
Price
LS-C152974-50
50 µg (1 mg/ml)
Unavailable

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Antibody
Species: Human, Mouse
Applications: Western blot, Flow Cytometry

Product Description

SPHK1 antibody LS-C152974 is an unconjugated rabbit polyclonal antibody to human SPHK1 (SPHK). Validated for IHC.
About SPHK / SPHK1
SPHK / SPHK1 catalyzes the phosphorylation of sphingosine to form sphingosine-1-phosphate (S1P), a lipid mediator with both intra- and extracellular functions. Intracellularly, S1P regulates proliferation and survival, and extracellularly, it is a ligand for cell surface G protein-coupled receptors. This protein, and its product S1P, play a key role in TNF-alpha signaling and the NF-kappa-B activation pathway important in inflammatory, antiapoptotic, and immune processes. Q9NYA1 NM_021972 NP_068807.2

SPHK1 Antibody, SK1 Antibody, Sphingosine kinase 1 Antibody, SPHK Antibody, SK 1 Antibody, SPK 1 Antibody, Sphingosine kinase type 1 Antibody, SPK Antibody


Specifications

Target
SPHK / SPHK1
Host
Rabbit
Reactivity
Human (tested or 100% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated
Purification
Affinity purified
Modifications
Unmodified
Applications
  • IHC (10 µg/ml)
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Immunogen
SPHK / SPHK1 antibody was raised against synthetic peptide conjugatd to KLH
Specificity
Recognizes an epitopewithin the N-terminal domain of humanSPHK1.
Presentation
PBS containing 0.1% sodium azide.
Storage
Short term: 4°C; Long term: -70°C.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Requested From: 
Date Requested: 6/19/2018

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