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Anti-SPHK / SPHK1 Antibody (aa176-225) LS-C146131

Ordering

Wt. Vol. Conc. Price
50 µg - - Unavailable

Most Popular SPHK / SPHK1 Antibodies

Anti-SPHK / SPHK1 Antibody (N-Terminus) IHC-plus™ LS-A3106
Rabbit Polyclonal to Human SPHK / SPHK1
Human, Monkey
IHC - Paraffin
Unconjugated
Immunohistochemistry Image
Anti-SPHK / SPHK1 Antibody (phospho-Ser225) LS-C26925
Rabbit Polyclonal to Mouse SPHK / SPHK1
Mouse
Western blot
Unconjugated
Western blot Image
Anti-SPHK / SPHK1 Antibody (aa176-189) LS-C87246
Goat Polyclonal to Human SPHK / SPHK1
Human, Monkey, Mouse, Hamster
Western blot, ELISA
Unconjugated
Western blot Image

100% Guaranteed 100% Guaranteed
Rabbit Polyclonal to Human SPHK / SPHK1
Human, Monkey, Mouse, Guinea pig, Horse
Western blot (applications tested for the base form of this product only)
Unconjugated

Details

Human SPHK / SPHK1
Rabbit
Human, Monkey, Mouse, Guinea pig, Horse (tested or 100% immunogen sequence identity)
Rat, Bovine, Dog, Rabbit (at least 90% immunogen sequence identity)
Polyclonal
Unconjugated. Also available conjugated with Biotin, FITC, HRP.
Immunoaffinity purified
Unmodified

Applications

  • Western blot
  • (applications tested for the base form of this product only)

Specificity and Use

SPHK / SPHK1 antibody was raised against synthetic peptide located between aa176-225 of human SPHK1 (Q9NYA1, NP_001136073). Percent identity by BLAST analysis: Human, Chimpanzee, Gorilla, Gibbon, Monkey, Galago, Mouse, Elephant (100%); Rat, Dog, Bovine, Rabbit, Platypus (92%); Bat, Horse, Guinea pig (85%); Opossum, Turkey, Chicken (84%).
LS-E23145 - Lyophilized - 100 µg - $145.00
Immunizing peptide used to generate LS-C146131. Useful for pre-absorption and neutralization of the antibody's antigen binding site.
aa176-225
Human SPHK1

Packaging

Lyophilized from PBS with 2% sucrose
Distilled water
Long term: -20°C, the use of 50% glycerol is recommended if storing aliquots in -20°C for long term use (up to 1 year); Short term (less than one week): +4°C. Avoid repeat freeze-thaw cycles.
For research use only.

About SPHK / SPHK1

Q9NYA1 NM_021972 NP_068807.2

SPHK1 Antibody, SK1 Antibody, Sphingosine kinase 1 Antibody, SPHK Antibody, SK 1 Antibody, SPK 1 Antibody, Sphingosine kinase type 1 Antibody, SPK Antibody

SPHK / SPHK1 catalyzes the phosphorylation of sphingosine to form sphingosine-1-phosphate (S1P), a lipid mediator with both intra- and extracellular functions. Intracellularly, S1P regulates proliferation and survival, and extracellularly, it is a ligand for cell surface G protein-coupled receptors. This protein, and its product S1P, play a key role in TNF-alpha signaling and the NF-kappa-B activation pathway important in inflammatory, antiapoptotic, and immune processes.

Western blot

Western blot
SPHK1 antibody LS-C146131 Western blot of Fetal Lung lysate. Antibody concentration 1 ug/ml. This image was taken for the unconjugated form of this product. Other forms have not been tested.
 

Requested From: 
Date Requested: 3/29/2017

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