Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
SP110 Antibody, IFI41 Antibody, IFI75 Antibody, Phosphoprotein 41 Antibody, VODI Antibody, Phosphoprotein 75 Antibody, SP110 nuclear body protein Antibody, Speckled 110 kDa Antibody, IPR1 Antibody
The nuclear body is a multiprotein complex that may have a role in the regulation of gene transcription. This gene is a member of the SP100/SP140 family of nuclear body proteins and encodes a leukocyte-specific nuclear body component. The protein can function as an activator of gene transcription and may serve as a nuclear hormone receptor coactivator. In addition, it has been suggested that the protein may play a role in ribosome biogenesis and in the induction of myeloid cell differentiation.
Western blot of SP110 expression in transfected 293T cell line by SP110 monoclonal antibody (M01), clone 8C8.
SP110 monoclonal antibody (M01), clone 8C8. Western blot of SP110 expression in Jurkat.
Immunoprecipitation of SP110 transfected lysate using anti-SP110 monoclonal antibody and Protein A Magnetic Bead.
Enzyme-Linked Immunosorbent Assay
Detection limit for recombinant GST tagged SP110 is approximately 0.1 ng/ml as a capture antibody.
Western blot of SP110 over-expressed 293 cell line, cotransfected with SP110 Validated Chimera RNAi (Lane 2) or non-transfected control (Lane 1). Blot probed with SP110 monoclonal antibody, clone 8C8. GAPDH ( 36.1 kD ) used as specificity.
Requested From: United States
Date Requested: 2/25/2017