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Anti-SP110 Antibody (aa265-279) IHC-plus™ LS-B4180

Note: This antibody replaces LS-C108398


Wt. Vol. Conc. Price
50 µg - 0.5 mg/ml Unavailable

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Goat Polyclonal to Human SP110
IHC - Paraffin


Human SP110
Human (tested or 100% immunogen sequence identity)
Monkey (at least 90% immunogen sequence identity)
Immunoaffinity purified


IHC - Paraffin (3.75 µg/ml)

Specificity and Use

SP110 antibody was raised against synthetic peptide C-PQEVSSTPSDKKGKK from an internal region of human SP110 (NP_004500.3; NP_004501.3; NP_536349.2). Percent identity with other species by BLAST analysis: Human (100%), Gorilla (93%), Marmoset (93%), Gibbon (87%).
LS-E27111 - Lyophilized - 100 µg - $145.00
Immunizing peptide used to generate LS-B4180. Useful for pre-absorption and neutralization of the antibody's antigen binding site.
Human SP110. This antibody is expected to recognize all three reported isoforms (NP_004500.3; NP_004501.3; NP_536349.2).
Immunohistochemistry: LS-B4180 was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for LS-B4180 was determined to be 3.75 ug/ml


Tris-buffered saline, pH 7.3, 0.5% BSA, 0.02% sodium azide
Store at -20°C. Minimize freezing and thawing.
For research use only.

About SP110

Q9HB58 NM_004510 NP_004501.3

SP110 Antibody, IFI41 Antibody, IFI75 Antibody, Phosphoprotein 41 Antibody, VODI Antibody, Phosphoprotein 75 Antibody, SP110 nuclear body protein Antibody, Speckled 110 kDa Antibody, IPR1 Antibody

The nuclear body is a multiprotein complex that may have a role in the regulation of gene transcription. This gene is a member of the SP100/SP140 family of nuclear body proteins and encodes a leukocyte-specific nuclear body component. The protein can function as an activator of gene transcription and may serve as a nuclear hormone receptor coactivator. In addition, it has been suggested that the protein may play a role in ribosome biogenesis and in the induction of myeloid cell differentiation.


Anti-SP110 antibody IHC of human tonsil. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B4180 concentration 3.75 ug/ml.


Anti-SP110 antibody IHC of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B4180 concentration 3.75 ug/ml.

Requested From: 
Date Requested: 4/24/2017

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