SP100

SP100 nuclear antigen

Together with PML, this tumor suppressor is a major constituent of the PML bodies, a subnuclear organelle involved in a large number of physiological processes including cell growth, differentiation and apoptosis. Functions as a transcriptional coactivator of ETS1 and ETS2 according to PubMed:11909962. Under certain conditions, it may also act as a corepressor of ETS1 preventing its binding to DNA according to PubMed:15247905. Through the regulation of ETS1 it may play a role in angiogenesis, controlling endothelial cell motility and invasion. Through interaction with the MRN complex it may be involved in the regulation of telomeres lengthening. May also regulate TP53-mediated transcription and through CASP8AP2, regulate FAS-mediated apoptosis. Also plays a role in infection by viruses, including human cytomegalovirus and Epstein-Barr virus, through mechanisms that may involve chromatin and/or transcriptional regulation.

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Products

Antibodies (58)

ELISA Kits (6)

Proteins (5)

Type

Primary (58)

Recombinant (5)

Sandwich (6)

Target

SP100 (69)

Reactivity

Human (44)

Mouse (16)

Rat (8)

Chicken (1)

Monkey (1)

Porcine (1)

Rabbit (1)

Application

IHC (5)

IHC-P (2)

WB (56)

ELISA (15)

ICC (3)

IF (3)

IP (1)

Peptide-ELISA (1)

Host

rabbit (52)

mouse (6)

Isotype

IgG (19)

IgG2a,k (6)

Clonality

monoclonal mc (6)

polyclonal pc (52)

Format

96-Well Strip Plate (6)

APC (3)

APC Conjugated (6)

Azide-free (1)

Biotin Conjugated (7)

Cy3 Conjugated (3)

Cy7 Conjugated (3)

FITC Conjugated (7)

HRP Conjugated (7)

PE Conjugated (6)

Unconjugated (19)

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Epitope

aa116-333 (8)

aa261-465 (8)

aa610-802 (8)

aa199-227 (7)

Internal (4)

250-330 aa, Internal (1)

aa1-480 (1)

aa1-99 (1)

Publications

No (69)

Sample Type

Plasma (2)

Serum (2)

Tag

GST (1)

GST, N-terminus (1)

His-T7 (3)

Species

Human (3)

Mouse (1)

Rat (1)

Source

E. coli (3)

Wheat Germ Extract (2)

Purification

Purified (1)

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SP100 Antibody (aa1-480) LS-C132167

Antibody:

SP100 Rabbit anti-Human Polyclonal (aa1-480) Antibody

Reactivity:

Mouse, Human

Applications:

WB

Format:

Unconjugated

Price:

100 µg/$749

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SP100 Antibody LS-C334338

Antibody:

SP100 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

IHC, WB

Format:

Unconjugated

Price:

20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503

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SP100 Antibody LS-C809380

Antibody:

SP100 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

IF, IHC, Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µl/$379; 200 µl/$421

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SP100 Antibody LS-C817333

Antibody:

SP100 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ICC, IF, IHC-P

Format:

Unconjugated

Price:

100 µl/$412

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SP100 Antibody (aa610-802) LS-C314466

Antibody:

SP100 Rabbit anti-Human Polyclonal (aa610-802) Antibody

Reactivity:

Human

Applications:

ICC, IP, WB

Format:

Unconjugated

Price:

100 µl/$299; 200 µl/$336; 500 µl/$462; 1 ml/$525; 2 ml/$677; 5 ml/$1,136

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SP100 Antibody LS-C752662

Antibody:

SP100 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

100 µg/$351

Select

SP100 Antibody (250-330 aa, Internal) LS-C386138

Antibody:

SP100 Rabbit anti-Human Polyclonal (250-330 aa, Internal) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

50 µg/$295; 100 µg/$335; 200 µg/$394

Select

SP100 Antibody LS-C817332

Antibody:

SP100 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ICC, IF, IHC-P

Format:

Unconjugated

Price:

100 µl/$412

Select

SP100 Antibody LS-C341908

Antibody:

SP100 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

IHC, WB

Format:

Unconjugated

Price:

50 µl/$338; 100 µl/$431

Select

SP100 Antibody (aa1-99) LS-C132168

Antibody:

SP100 Mouse anti-Human Monoclonal (aa1-99) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

100 µg/$705

Select

SP100 Antibody (HRP) LS-C549535

Antibody:

SP100 Mouse anti-Human Monoclonal (HRP) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

HRP Conjugated

Price:

100 µl/$904

Select

SP100 Antibody (Biotin) LS-C529446

Antibody:

SP100 Mouse anti-Human Monoclonal (Biotin) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Biotin Conjugated

Price:

100 µl/$904

Select

SP100 Antibody (FITC) LS-C539366

Antibody:

SP100 Mouse anti-Human Monoclonal (FITC) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

FITC Conjugated

Price:

100 µl/$904

Select

SP100 Antibody (APC) LS-C519293

Antibody:

SP100 Mouse anti-Human Monoclonal (APC) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

APC Conjugated

Price:

100 µl/$904

Select

SP100 Antibody (PE) LS-C657512

Antibody:

SP100 Mouse anti-Human Monoclonal (PE) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

PE Conjugated

Price:

100 µl/$904

• Unconjugated
• HRP
• Biotin
• FITC
• APC
• PE

• Unconjugated
• HRP
• Biotin
• More...
  • FITC
  • APC
  • PE

Select

SP100 Antibody (aa199-227) LS-C325293

Antibody:

SP100 Rabbit anti-Human Polyclonal (aa199-227) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

200 µl/$734

Select

SP100 Antibody (aa199-227, Biotin) LS-C270051

Antibody:

SP100 Rabbit anti-Human Polyclonal (aa199-227) (Biotin) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Biotin Conjugated

Price:

200 µl/$952

Select

SP100 Antibody (aa199-227, FITC) LS-C270052

Antibody:

SP100 Rabbit anti-Human Polyclonal (aa199-227) (FITC) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

FITC Conjugated

Price:

200 µl/$952

Select

SP100 Antibody (aa199-227, Azide-free, HRP) LS-C270053

Antibody:

SP100 Rabbit anti-Human Polyclonal (aa199-227) (Azide-free) (HRP) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

HRP Conjugated, Azide-free

Price:

200 µl/$952

Select

SP100 Antibody (aa199-227, APC) LS-C270050

Antibody:

SP100 Rabbit anti-Human Polyclonal (aa199-227) (APC) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

APC Conjugated

Price:

200 µl/$952

Select

SP100 Antibody (aa199-227, PE) LS-C270054

Antibody:

SP100 Rabbit anti-Human Polyclonal (aa199-227) (PE) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

PE Conjugated

Price:

200 µl/$952

• Unconjugated
• Biotin
• FITC
• HRP, Azide-free
• APC
• PE

• Unconjugated
• Biotin
• FITC
• More...
  • HRP, Azide-free
  • APC
  • PE

Select

SP100 Antibody LS-C824345

Antibody:

SP100 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

100 µg/$357

Select

SP100 Antibody (aa261-465) LS-C296479

Antibody:

SP100 Rabbit anti-Mouse Polyclonal (aa261-465) Antibody

Reactivity:

Mouse

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$301; 200 µl/$340; 500 µl/$470; 1 ml/$535; 2 ml/$698; 5 ml/$1,161

Select

SP100 Antibody LS-C770828

Antibody:

SP100 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

WB

Format:

Unconjugated

Price:

60 µl/$331; 120 µl/$403; 200 µl/$529

Select

SP100 Antibody LS-C484848

Antibody:

SP100 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$412

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