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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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SOX18 Antibody (aa192‑241) LS‑C30917
SOX18 antibody LS-C30917 is an unconjugated rabbit polyclonal antibody to SOX18 from human, mouse, rat and other species. Validated for WB.
Catalog
Size
Price
LS-C30917-100
100 µg (1 mg/ml)
Unavailable

Popular SOX18 Products

SOX18 antibody LS-C30068 was used in IHC to stain formalin-fixed, paraffin-embedded human kidney.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Species: Human, Mouse, Rat, Bovine, Guinea pig, Hamster, Pig
Applications: IHC, IHC - Paraffin, Western blot
Anti-SOX18 antibody IHC of human uterus. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B3089 concentration 10 ug/ml.
Species: Human, Monkey
Applications: IHC, IHC - Paraffin, Western blot
Fluorescent confocal image of HeLa cell stained with SOX18 Antibody. HeLa cells were fixed with 4% PFA (20 min), permeabilized with Triton X-100 (0.1%, 10 min), then incubated with SOX18 primary antibody (1:25, 1 h at 37°C). For secondary antibody, Alexa Fluor 488 conjugated donkey anti-rabbit antibody (green) was used (1:400, 50 min at 37°C). Cytoplasmic actin was counterstained with Alexa Fluor 555 (red) conjugated Phalloidin (7units/ml, 1 h at 37°C). Nuclei were counterstained with DAPI (blue) (10 ug/ml, 10 min). SOX18 immunoreactivity is localized to Nucleus significantly.
Species: Human
Applications: Immunofluorescence, Western blot
Antibody
Species: Human
Applications: Western blot, ELISA
SOX18 antibody LS-C30068 was used in IHC to stain formalin-fixed, paraffin-embedded human kidney.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Species: Human, Chimpanzee, Gibbon, Mouse, Rat, Bovine, Guinea pig, Hamster, Pig
Applications: IHC, IHC - Paraffin, Western blot

Product Description

SOX18 antibody LS-C30917 is an unconjugated rabbit polyclonal antibody to SOX18 from human, mouse, rat and other species. Validated for WB.
About SOX18
SOX18 is a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional regulator after forming a protein complex with other proteins. This protein plays a role in hair, blood vessel, and lymphatic vessel development. Mutations in this gene have been associated with recessive and dominant forms of hypotrichosis-lymphedema-telangiectasia. P35713 NM_018419 NP_060889.1

SOX18 Antibody, Transcription factor SOX-18 Antibody, Sox-8 Antibody, SRY-box 18 Antibody, HLTS Antibody


Specifications

Target
Human SOX18
Host
Rabbit
Reactivity
Human, Mouse, Rat, Guinea pig, Pig (tested or 100% immunogen sequence identity)
Predicted
Monkey, Bovine (at least 90% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated. Also available conjugated with Biotin, HRP, FITC.
Purification
Protein A/G purified
Modifications
Unmodified
Applications
  • Western blot (2 µg/ml)
  • (applications tested for the base form of this product only)
Immunogen
SOX18 antibody was raised against synthetic peptide located between aa192-241 of human SOX18 (P35713, NP_060889). Percent identity by BLAST analysis: Human, Chimpanzee, Gibbon, Monkey, Pig, Guinea pig (100%); Marmoset, Bovine (92%); Galago (91%); Mouse, Rat, Hamster (84%).
Blocking Peptide
LS-E11643 - Lyophilized - 100 µg - $145.00
Immunizing peptide used to generate LS-C30917. Useful for pre-absorption and neutralization of the antibody's antigen binding site.
Epitope
aa192-241
Specificity
Human SOX18
Presentation
Lyophilized from PBS with 2% sucrose
Reconstitution
200 µl After adding water, will consist of PBS buffer with 2% sucrose
Storage
Long term: -20°C, the use of 50% glycerol is recommended if storing aliquots in -20°C for long term use (up to 1 year); Short term (less than 1 week): 4°C. Avoid freeze-thaw cycles.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Images


Western blot

Jurkat Cell Lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Jurkat Cell Lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Western blot

Jurkat Cell Lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Jurkat Cell Lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Western blot

Jurkat Cell Lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Jurkat Cell Lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Western blot

Jurkat Cell Lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Jurkat Cell Lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.


Requested From: 
Date Requested: 6/24/2018

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