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Anti-SOS1 Antibody (clone SOS-1) LS-C188432


Wt. Vol. Conc. Price
100 µg - 1 mg/ml $290
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)

Most Popular SOS1 Antibodies

Anti-SOS1 Antibody (aa1186-1200) IHC-plus™ LS-B4169
Goat Polyclonal to Human SOS1
Human, Monkey, Mouse, Bat, Bovine, Dog, Pig, Rabbit
IHC - Paraffin
Immunohistochemistry Image
Anti-SOS1 Antibody LS-C132160
Mouse Monoclonal (IgG1) to Human SOS1
Human, Monkey, Mouse, Bat, Bovine, Horse, Pig, Rabbit
Immunofluorescence, Western blot, ELISA
Anti-SOS1 Antibody (clone SOS-1) LS-C188432
Mouse Monoclonal [clone SOS-1] (IgG1) to Human SOS1
Human, Monkey, Mouse, Rat, Bovine, Guinea pig, Horse, Pig, Rabbit
Immunofluorescence, Western blot, ELISA

100% Guaranteed 100% Guaranteed
Mouse Monoclonal [clone SOS-1] (IgG1) to Human SOS1
Human, Monkey, Mouse, Rat, Bovine, Guinea pig, Horse, Pig, Rabbit
Immunofluorescence, Western blot, ELISA


Human SOS1
Human, Monkey, Mouse, Rat, Bovine, Guinea pig, Horse, Pig, Rabbit (tested or 100% immunogen sequence identity)
Dog (at least 90% immunogen sequence identity)
IgG1 Monoclonal [SOS-1]
Protein A purified


  • Immunofluorescence
  • Western blot (1 µg/ml)

Specificity and Use

SOS1 antibody was raised against synthetic peptide corresponding to amino acids THPSMHRDGPPLLENAHSS of human SOS1. Percent identity by BLAST analysis: Human, Chimpanzee, Gorilla, Orangutan, Gibbon, Monkey, Galago, Marmoset, Mouse, Rat, Ferret, Elephant, Panda, Bovine, Cat, Horse, Rabbit, Opossum, Guinea pig (100%); Dog, Turkey, Zebra finch (95%); Lizard (89%).
Recognizes SOS1 (son of sevenless homolog 1), a ubiquitously expressed 150kD intracellular protein and bifunctional guanine nucleotide exchange factor (GEF), which plays a role in growth and differentiation signalling pathways and in actin reorganization, by acting as a regulator of Ras and Rac/Rho GTPases. Mutations in the SOS1 gene are responsible for the rare oral overgrowth condition known as gingival fibromatosis 1 (GINGF1), and also the cause of the relatively common autosomal dominant disorder Noonan syndrome type 4 (NS4), characterized by short stature, congenital heart malformation, bleeding diathesis and distinctive facial features.


PBS, 0.09% sodium azide
+4°C or -20°C, Avoid repeated freezing and thawing.
For research use only.

About SOS1

Q07889 NM_005633 NP_005624.2

SOS1 Antibody, GINGF Antibody, NS4 Antibody, SOS-1 Antibody, Son of sevenless homolog 1 Antibody, GF1 Antibody, GGF1 Antibody

Promotes the exchange of Ras-bound GDP by GTP. Catalytic component of a trimeric complex that participates in transduction of signals from Ras to Rac by promoting the Rac-specific guanine nucleotide exchange factor (GEF) activity.

Requested From: United States
Date Requested: 10/21/2016

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