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Anti-SOS1 Antibody (aa1243-1258) LS-C10294

Catalog Size Price
LS-C10294-200 200 µg (1 mg/ml) Unavailable

Related Products

27 SOS1 Antibodies

Most Popular SOS1 Antibodies

Anti-SOS1 Antibody (aa1243-1258) LS-C10294
Rabbit Polyclonal (IgG) to Human SOS1
Human, Monkey, Mouse, Dog, Horse, Rabbit
Western blot, Immunoprecipitation
Unconjugated
Anti-SOS1 Antibody LS-C132160
Mouse Monoclonal (IgG1) to Human SOS1
Human, Monkey, Mouse, Bat, Bovine, Horse, Pig, Rabbit
Immunofluorescence, Western blot, ELISA
Unconjugated
Anti-SOS1 Antibody (clone SOS-1) LS-C188432
Mouse Monoclonal [clone SOS-1] (IgG1) to Human SOS1
Human, Monkey, Mouse, Rat, Bovine, Guinea pig, Horse, Pig, Rabbit
Immunofluorescence, Western blot, ELISA
Unconjugated
Anti-SOS1 Antibody LS-C681428
Rabbit Polyclonal (IgG) to Human SOS1
Human
IHC, Immunofluorescence, Western blot, ELISA
Unconjugated
Immunohistochemistry Dilution at 1:400 and staining in paraffin-embedded human placenta tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal Goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated Secondary antibody and visualized using an HRP conjugated SP system.
Anti-SOS1 Antibody (aa1283-1333) IHC-plus™ LS-B15465
Rabbit Polyclonal (IgG) to Human SOS1
Human, Mouse
IHC, IHC - Paraffin, Western blot, Immunoprecipitation
Unconjugated
Human Colon, Submucosal Plexus: Formalin-Fixed, Paraffin-Embedded (FFPE), at a dilution of 1:100.

100% Guaranteed Publications (1)
Rabbit Polyclonal (IgG) to Human SOS1
Human, Monkey, Mouse, Dog, Horse, Rabbit
Western blot, Immunoprecipitation (applications tested for the base form of this product only)
Unconjugated

Details

Human SOS1
Rabbit
Human, Monkey, Mouse, Dog, Horse, Rabbit (tested or 100% immunogen sequence identity)
Bat, Bovine, Pig (at least 90% immunogen sequence identity)
IgG Polyclonal
Unconjugated. Also available conjugated with AP, APC, Biotin, FITC, HRP, PE.
Protein A purified
Unmodified

Applications

  • Western blot (0.5 - 1 µg/ml)
  • Immunoprecipitation
  • (applications tested for the base form of this product only)

Specificity and Use

SOS1 antibody was raised against kLH-conjugated, synthetic peptide corresponding to amino acids 1243-1258 (KKSDHGNAFFPNSPSP) of murine Son of Sevenless Homolog 1 Protein (SOS 1). The immunizing sequence is identical in human. Percent identity by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Marmoset, Mouse, Elephant, Panda, Dog, Horse, Rabbit (100%); Bovine, Bat, Pig (94%); Opossum (88%).
aa1243-1258
Recognizes SOS 1, Mr 175kD. Species cross-reactivity: Mouse and human. Other species not tested.
Suitable for use in Western Blot and Immunoprecipitation. Western Blot: 0.5-1 ug/ml. Immunoprecipitation: 5 ug. Positive control: F4209: Fibroblast Cell, 3T3/A31. Add 2.5 ul of 2-mercaptoethanol/100 ul of lysate and boil for 5 minutes to reduce the preparation. Load 20 ug of reduced lysate per lane for minigels.

Packaging

0.1 M Tris, pH 8.0, 0.15 M sodium chloride, 0.1 mM EDTA, 0.05% sodium azide, 30% glycerol.
4°C or -20°C, Avoid freeze-thaw cycles.
For research use only.

Publications (1)

1
Lentiviral vector-based insertional mutagenesis identifies genes associated with liver cancer. Ranzani M, Cesana D, Bartholomae CC, Sanvito F, Pala M, Benedicenti F, Gallina P, Sergi LS, Merella S, Bulfone A, Doglioni C, von Kalle C, Kim YJ, Schmidt M, Tonon G, Naldini L, Montini E. Nature methods. 2013 10:155-61. (WB; Human) [Full Text Article] [PubMed:23314173] [PMC:PMC3589714]

About SOS1

Q07889 NM_005633 NP_005624.2

SOS1 Antibody, GINGF Antibody, NS4 Antibody, SOS-1 Antibody, Son of sevenless homolog 1 Antibody, GF1 Antibody, GGF1 Antibody

Promotes the exchange of Ras-bound GDP by GTP. Catalytic component of a trimeric complex that participates in transduction of signals from Ras to Rac by promoting the Rac-specific guanine nucleotide exchange factor (GEF) activity.

Requested From: 
Date Requested: 5/20/2018

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