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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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SORBS1 / Ponsin Antibody (aa1282‑1294) IHC‑plus™ LS‑B1762 Best Seller
Note: This antibody replaces LS-C47543
Ponsin antibody LS-B1762 is an unconjugated goat polyclonal antibody to Ponsin (SORBS1) from human, mouse, rat and other species. Validated for IHC and Peptide-ELISA. Tested on 20 paraffin-embedded human tissues.
Catalog
Size
Price
LS-B1762-50
50 µg (0.5 mg/ml)
$425

Popular SORBS1 / Ponsin Products

Anti-SORBS1 antibody IHC of human skeletal muscle. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B1763 concentration 5 ug/ml.
Species: Human, Monkey, Dog, Horse
Applications: IHC, IHC - Paraffin, Peptide Enzyme-Linked Immunosorbent Assay
Anti-SORBS1 antibody IHC of human liver. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B4347 concentration 3.75 ug/ml.
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Antibody
Species: Human, Hamster
Applications: ICC, Immunofluorescence, Western blot, ELISA
Antibody
Species: Human, Hamster
Applications: ICC, Immunofluorescence, Western blot, ELISA

Product Description

Ponsin antibody LS-B1762 is an unconjugated goat polyclonal antibody to Ponsin (SORBS1) from human, mouse, rat and other species. Validated for IHC and Peptide-ELISA. Tested on 20 paraffin-embedded human tissues.
About SORBS1 / Ponsin
Plays a role in tyrosine phosphorylation of CBL by linking CBL to the insulin receptor. Required for insulin-stimulated glucose transport. Involved in formation of actin stress fibers and focal adhesions. Q9BX66 NM_015385 NP_056200.1

SORBS1 Antibody, C-Cbl associated protein Antibody, C-Cbl-associated protein Antibody, CAP Antibody, FLAF2 Antibody, KIAA0894 Antibody, KIAA1296 Antibody, R85FL Antibody, SH3 domain protein 5 Antibody, SH3-domain protein 5 (ponsin) Antibody, SH3P12 Antibody, SORB1 Antibody, Fas-ligand associated factor 2 Antibody, Ponsin Antibody, SH3D5 Antibody


Specifications

Target
Human SORBS1 / Ponsin
Host
Goat
Reactivity
Human, Monkey, Mouse, Rat, Bat, Dog, Hamster, Horse (tested or 100% immunogen sequence identity)
Predicted
Pig, Chicken (at least 90% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated
Purification
Immunoaffinity purified
Modifications
Unmodified
Applications
  • IHC
  • IHC - Paraffin (2.5 µg/ml)
  • Peptide Enzyme-Linked Immunosorbent Assay (1:16000)
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Immunogen
SORBS1 / Ponsin antibody was raised against synthetic peptide C-GTFPGNYVKPLYL from the C-terminus of human SORBS1 (NP_006425.2; NP_056200.1; NP_001030126.1; NP_001030127.1; NP_001030128.1; NP_079267.1; NP_001030129.1). Percent identity by BLAST analysis: Human, Gorilla, Orangutan, Gibbon, Monkey, Marmoset, Mouse, Rat, Dog, Bat, Hamster, Elephant, Panda, Horse, Opossum, Platypus (100%); Pig, Turkey, Chicken (92%); Zebrafish (85%).
Blocking Peptide
LS-E25367 - Lyophilized - 100 µg - $145.00
Immunizing peptide used to generate LS-B1762. Useful for pre-absorption and neutralization of the antibody's antigen binding site.
Epitope
aa1282-1294
Specificity
Human SORBS1. This antibody is expected to recognize all seven reported isoforms (NP_006425.2, NP_056200.1, NP_001030126.1, NP_001030127.1, NP_001030128.1, NP_079267.1 and NP_001030129.1).
Usage
Immunohistochemistry: LS-B1762 was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for LS-B1762 was determined to be 2.5 ug/ml.
Presentation
TBS, pH 7.3, 0.02% Sodium Azide, 0.5% BSA
Storage
Store at -20°C. Avoid freeze-thaw cycles.
Restrictions
For research use only.

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Immunohistochemistry

Anti-SORBS1 antibody IHC of human skeletal muscle. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B1762 concentration 5 ug/ml.
Anti-SORBS1 antibody IHC of human skeletal muscle. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B1762 concentration 5 ug/ml.

Immunohistochemistry

Anti-SORBS1 antibody IHC of human skeletal muscle. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B1762 concentration 5 ug/ml.
Anti-SORBS1 antibody IHC of human skeletal muscle. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B1762 concentration 5 ug/ml.

Immunohistochemistry

Anti-SORBS1 antibody IHC of human skeletal muscle. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B1762 concentration 5 ug/ml.
Anti-SORBS1 antibody IHC of human skeletal muscle. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B1762 concentration 5 ug/ml.

Immunohistochemistry

Anti-SORBS1 antibody IHC of human skeletal muscle. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B1762 concentration 5 ug/ml.
Anti-SORBS1 antibody IHC of human skeletal muscle. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B1762 concentration 5 ug/ml.

Requested From: United States
Date Requested: 9/18/2018

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