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SOD2 / Mn SOD
superoxide dismutase 2, mitochondrial
MNSOD / SOD2 is a member of the iron/manganese superoxide dismutase family. It encodes a mitochondrial protein that forms a homotetramer and binds one manganese ion per subunit. This protein binds to the superoxide byproducts of oxidative phosphorylation and converts them to hydrogen peroxide and diatomic oxygen. Mutations in this gene have been associated with idiopathic cardiomyopathy (IDC), premature aging, sporadic motor neuron disease, and cancer. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
| Gene Name: | superoxide dismutase 2, mitochondrial |
| Synonyms: | SOD2, IPOB, MVCD6, Indophenoloxidase B, Mn superoxide dismutase, MNSOD, Mangano-superoxide dismutase |
| Target Sequences: | NM_000636 NP_000627.2 P04179 |
Publications (4)
1
A novel Drosophila SOD2 mutant demonstrates a role for mitochondrial ROS in neurodevelopment and disease. Celotto AM, Liu Z, Vandemark AP, Palladino MJ. Brain and behavior. 2012 2:424-34. (WB; Rat)
[Full Text Article]
[PubMed:22950046]
[PMC:PMC3432965]
Related Antibodies: LS-B3694.
2
Production of functional classical brown adipocytes from human pluripotent stem cells using specific hemopoietin cocktail without gene transfer. Nishio M, Yoneshiro T, Nakahara M, Suzuki S, Saeki K, Hasegawa M, Kawai Y, Akutsu H, Umezawa A, Yasuda K, Tobe K, Yuo A, Kubota K, Saito M, Saeki K. Cell metabolism. 2012 16:394-406. (IHC; Human)
[Full Text Article]
[PubMed:22958922]
3
Monosodium luminol reinstates redox homeostasis, improves cognition, mood and neurogenesis, and alleviates neuro- and systemic inflammation in a model of Gulf War Illness. Shetty AK, Attaluri S, Kodali M, Shuai B, Shetty GA, Upadhya D, Hattiangady B, Madhu LN, Upadhya R, Bates A, Rao X. Redox biology. 2020 January;28: [Full Text Article]
[PubMed:31778892]
[PMC:PMC6888767]
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SOD2 / Mn SOD Rabbit anti-Rat Polyclonal Antibody
Xenopus, Drosophila, Pig, Rat, Hamster, Rabbit, Mouse, Dog, Guinea pig, Sheep, Bovine, Human, Monkey
Flo, IHC, IHC-P, IP, WB
Unconjugated
50 µg/$485
SOD2 / Mn SOD Rabbit anti-Human Polyclonal Antibody
Xenopus, Rat, Hamster, Pig, Rabbit, Mouse, Dog, Sheep, Bovine, Human, Monkey
ELISA, WB
Unconjugated
50 µg/$582; 200 µg/$896
Mammalian Cells
6His, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
23.2 kDa
10 µg/$368; 50 µg/$479
Sandwich
96-Well Strip Plate
Rat
31.2 - 2000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates
1 Plate/$856
Sandwich
96-Well Strip Plate
Human
0.78 - 50 ng/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum, Tissue Homogenates
1 Plate/$798
Neuroscience
SOD2 / Mn SOD Mouse anti-Human Monoclonal Antibody
Mouse, Rat, Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µl/$440
Sandwich
96-Well Strip Plate
Mouse
0.313 - 20 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
E. coli
His
Biologically active
100 µg/$342; 500 µg/$641; 20 µg/$254
Neuroscience
SOD2 / Mn SOD Goat anti-Human Polyclonal (aa119-130) Antibody
Mouse, Rat, Pig, Human
IHC-P, Peptide-ELISA, WB
Unconjugated
50 µg/$460
Neuroscience
SOD2 / Mn SOD Rabbit anti-Rat Polyclonal Antibody
Xenopus, Chicken, Drosophila, Pig, Rat, Hamster, Sheep, Bovine, Rabbit, Mouse, Dog, Guinea pig, Human, Monkey
ELISA, IF, IHC, IHC-P, IP, WB
Unconjugated
50 µg/$440
SOD2 / Mn SOD Rabbit anti-Rat Polyclonal (Atto 488) Antibody
Xenopus, Chicken, Drosophila, Pig, Rat, Hamster, Sheep, Bovine, Rabbit, Mouse, Dog, Guinea pig, Human, Monkey
ELISA, IF, IHC, IHC-P, IP, WB
Atto 488 Conjugated
100 µg/$489
SOD2 / Mn SOD Rabbit anti-Human Polyclonal (aa64-175) Antibody
Mouse, Rat, Human
ELISA, IF, IHC-P, IP, WB
Unconjugated
50 µg/$460
SOD2 / Mn SOD Mouse anti-Human Monoclonal Antibody
Mouse, Rat, Human
ICC, IHC, IHC-Fr, WB
Unconjugated
100 µg/$832
Neuroscience
SOD2 / Mn SOD Goat anti-Human Polyclonal (aa77-91) Antibody
Human
IHC-P, Peptide-ELISA, WB
Unconjugated
50 µg/$460
Neuroscience
SOD2 / Mn SOD Rabbit anti-Human Polyclonal Antibody
Mouse, Bovine, Rat, Human
IHC, IHC-P, WB
Unconjugated
50 µg/$675
Neuroscience
SOD2 / Mn SOD Rabbit anti-Human Polyclonal Antibody
Xenopus, Chicken, Sheep, Bovine, Rabbit, Mouse, Dog, Guinea pig, Gerbil, Rat, Hamster, Pig, Human, Monkey
ELISA, IHC, IHC-P, IP, WB
Unconjugated
50 µg/$440
SOD2 / Mn SOD Rabbit anti-Human Polyclonal (APC) Antibody
Xenopus, Chicken, Sheep, Bovine, Rabbit, Mouse, Dog, Guinea pig, Gerbil, Rat, Hamster, Pig, Human, Monkey
ELISA, IHC, IHC-P, IP, WB
APC Conjugated
100 µg/$488
SOD2 / Mn SOD Rabbit anti-Human Polyclonal (RPE) Antibody
Xenopus, Chicken, Sheep, Bovine, Rabbit, Mouse, Dog, Guinea pig, Gerbil, Rat, Hamster, Pig, Human, Monkey
ELISA, IHC, IHC-P, IP, WB
RPE Conjugated
100 µg/$487
Neuroscience
SOD2 / Mn SOD Mouse anti-Human Monoclonal (37CT127.5.11.6) Antibody
Human
IHC, IHC-P, WB
Unconjugated
200 µl/$440
SOD2 / Mn SOD Mouse anti-Human Monoclonal (8H3F9) Antibody
Human
ELISA, Flo, IHC, WB
Unconjugated
100 µl/$459
SOD2 / Mn SOD Mouse anti-Human Monoclonal (8H3D2) Antibody
Human
ELISA, Flo, IF, IHC, WB
Unconjugated
100 µl/$459
SOD2 / Mn SOD Rabbit anti-Human Polyclonal (aa45-62) Antibody
Mouse, Rat, Human
ICC, IHC, IHC-P, WB
Unconjugated
10 µg/$318; 100 µg/$470
SOD2 / Mn SOD Mouse anti-Human Monoclonal (1559CT572.3.83) Antibody
Mouse, Human
Flo, IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
200 µl/$393
SOD2 / Mn SOD Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF, IHC, IP, WB
Unconjugated
100 µg/$341
SOD2 / Mn SOD Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, IHC, WB
Unconjugated
20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503
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