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Anti-SOD1 / Cu-Zn SOD Antibody (aa69-81) LS-C55508

Catalog	Size	Price
LS-C55508-100	100 µg (0.5 mg/ml)	Unavailable

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Anti-SOD1 / Cu-Zn SOD Antibody IHC-plus™ LS-B3693

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Anti-SOD1 / Cu-Zn SOD Antibody (clone 1H12) LS-C194684

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Antibody:	Goat Polyclonal to Human SOD1 / Cu-Zn SOD
Reactivity:	Human, Mouse
Application:	Western blot, ELISA
Format:	Unconjugated

Details

Target:	Human SOD1 / Cu-Zn SOD
Host:	Goat
Reactivity:	Human, Mouse (tested or 100% immunogen sequence identity)
Predicted:	Monkey, Bovine, Goat, Horse, Rabbit, Sheep (at least 90% immunogen sequence identity)
Clonality:	Polyclonal
Conjugations:	Unconjugated
Purification:	Immunoaffinity purified
Modifications:	Unmodified

Applications

Approved:

Western blot (0.01 - 0.03 µg/ml)
ELISA (1:8000)

Failed:

IHC - Paraffin

Specificity and Use

Immunogen:

Synthetic peptide C-SRKHGGPKDEERH from an internal region of human SOD1 (NP_000445.1). Percent identity by BLAST analysis: Human, Chimpanzee, Gorilla, Orangutan, Gibbon (100%); Monkey, Marmoset, Sheep, Goat, Panda, Bovine, Horse, Rabbit (92%); Mouse, Rat, Dog, Pig, Opossum, Guinea pig (85%).

Blocking Peptide:

LS-E26076 - Lyophilized - 100 µg - $145.00
Immunizing peptide used to generate LS-C55508. Useful for pre-absorption and neutralization of the antibody's antigen binding site.

Epitope:

aa69-81

Specificity:

Human SOD1.

Packaging

Presentation:	Tris-buffered saline, pH 7.3, 0.5% BSA, 0.02% sodium azide
Storage:	Store at -20°C. Avoid freeze-thaw cycles.
Restrictions:	For research use only.

About SOD1 / Cu-Zn SOD

Uniprot: P00441 NCBI: NM_000454 NP_000445.1

Synonyms: SOD1 Antibody, ALS Antibody, ALS1 Antibody, Cu/Zn superoxide dismutase Antibody, HSod1 Antibody, Homodimer Antibody, IPOA Antibody, SOD, soluble Antibody, SOD Antibody, Superoxide dismutase [Cu-Zn] Antibody, Superoxide dismutase 1 Antibody, Indophenoloxidase A Antibody, Superoxide dismutase, cystolic Antibody

Description: SOD1 / Cu-Zn SOD binds copper and zinc ions and is one of two isozymes responsible for destroying free superoxide radicals in the body. The encoded isozyme is a soluble cytoplasmic protein, acting as a homodimer to convert naturally-occuring but harmful superoxide radicals to molecular oxygen and hydrogen peroxide. The other isozyme is a mitochondrial protein. Mutations in this gene have been implicated as causes of familial amyotrophic lateral sclerosis.

(More About SOD1 / Cu-Zn SOD)

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Technical Help Review

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Western blot

Antibody (0.02 ug/ml) staining of Mouse Brain lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Requested From:
Date Requested: 10/22/2017

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