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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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SOCS3 Antibody (clone 1B2) LS‑C179705
SOCS3 antibody LS-C179705 is an unconjugated mouse monoclonal antibody to mouse SOCS3. Validated for WB.
Catalog
Size
Price
LS-C179705-100
100 µg (1 mg/ml)
Unavailable

Popular SOCS3 Products

Antibody staining (5 ug/ml) of MOLT-4 lysate (RIPA buffer, 30 ug total protein per lane). Primary incubated for 1 hour. Detected by Western blot of chemiluminescence.
Species: Human, Monkey, Mouse, Rat, Bat, Bovine, Hamster, Horse, Pig, Rabbit
Applications: Western blot
Anti-SOCS3 antibody IHC of human colon. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B3317 concentration 10 ug/ml.
Species: Human
Applications: IHC, IHC - Paraffin, Western blot, ELISA
Anti-SOCS3 mouse monoclonal antibody immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY SOCS3.
Species: Human
Applications: Immunofluorescence, Western blot, Flow Cytometry
Western blot of recombinant SOCS3.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Species: Mouse
Applications: IHC, Western blot
Western blot analysis of SOCS3 expression in MOLT4 (A); A431 (B); MCF7 (C); Raw264.7 (D); H9C2 (E) whole cell lysates.
Species: Human, Mouse, Rat, Bovine, Dog, Pig, Sheep, Chicken
Applications: Western blot

Product Description

SOCS3 antibody LS-C179705 is an unconjugated mouse monoclonal antibody to mouse SOCS3. Validated for WB.
About SOCS3
SOCS family proteins form part of a classical negative feedback system that regulates cytokine signal transduction. SOCS3 is involved in negative regulation of cytokines that signal through the JAK/STAT pathway. Inhibits cytokine signal transduction by binding to tyrosine kinase receptors including gp130, LIF, erythropoietin, insulin, IL12, GCSF and leptin receptors. Binding to JAK2 inhibits its kinase activity. Suppresses fetal liver erythropoiesis. O14543 NM_003955 NP_003946.3

SOCS3 Antibody, Cish3 Antibody, Cytokine-induced SH2 protein 3 Antibody, CIS-3 Antibody, CIS3 Antibody, SSI-3 Antibody, STAT-induced STAT inhibitor 3 Antibody, SSI3 Antibody, ATOD4 Antibody, SOCS-3 Antibody


Specifications

Target
Mouse SOCS3
Host
Mouse
Reactivity
Mouse (tested or 100% immunogen sequence identity)
Clonality
IgG1 Monoclonal [1B2]
Conjugations
Unconjugated
Purification
Protein A purified
Modifications
Unmodified
Applications
  • Western blot (0.5 µg/ml)
Immunogen
SOCS3 antibody was raised against recombinant Mouse SOCS-3 (2-44 a. a.).
Specificity
Mouse SOCS3
Presentation
PBS, pH 7.2, 50% glycerol
Storage
Store at -20°C.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Immunoprecipitation

Immunoprecipitation

Immunoprecipitation

Immunoprecipitation



Requested From: 
Date Requested: 6/21/2018

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