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Anti-SOCS3 Antibody (C-Terminus) IHC-plus™ LS-B3373

Note: This antibody replaces LS-C50503


Wt. Vol. Conc. Price
- 250 µl - $395
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)

Most Popular SOCS3 Antibodies

Anti-SOCS3 Antibody (aa213-225) LS-C55482
Goat Polyclonal to Human SOCS3
Human, Monkey, Mouse, Rat, Bat, Bovine, Hamster, Horse, Pig, Rabbit
Western blot
Western blot Image
Anti-SOCS3 Antibody (clone 11C5) LS-C172981
Mouse Monoclonal [clone 11C5] (IgG1) to Human SOCS3
Immunofluorescence, Western blot, Flow Cytometry
Immunofluorescence Image
Anti-SOCS3 Antibody (aa1-225, Biotin) LS-C297684
Rabbit Polyclonal (IgG) to Mouse SOCS3
Western blot, ELISA
Biotin Conjugated
Western blot Image

100% Guaranteed 100% Guaranteed
Rabbit Polyclonal to Human SOCS3
IHC - Paraffin


Human SOCS3
Human (tested or 100% immunogen sequence identity)
Immunoaffinity purified


IHC - Paraffin (10 µg/ml)

Specificity and Use

SOCS3 antibody was raised against synthetic peptide corresponding to C-terminal of human SOCS-3 protein.
Immunohistochemistry: LS-B3373 was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for LS-B3373 was determined to be 10 ug/ml.


10mM PBS/1% BSA buffer pH 7.4 with 0.1% sodium azide.
Store at 2°C to 8°C degrees. Do not freeze.
For research use only.

About SOCS3

O14543 NM_003955 NP_003946.3

SOCS3 Antibody, Cish3 Antibody, Cytokine-induced SH2 protein 3 Antibody, CIS-3 Antibody, CIS3 Antibody, SSI-3 Antibody, STAT-induced STAT inhibitor 3 Antibody, SSI3 Antibody, ATOD4 Antibody, SOCS-3 Antibody

SOCS family proteins form part of a classical negative feedback system that regulates cytokine signal transduction. SOCS3 is involved in negative regulation of cytokines that signal through the JAK/STAT pathway. Inhibits cytokine signal transduction by binding to tyrosine kinase receptors including gp130, LIF, erythropoietin, insulin, IL12, GCSF and leptin receptors. Binding to JAK2 inhibits its kinase activity. Suppresses fetal liver erythropoiesis.


Anti-SOCS3 antibody IHC of human skeletal muscle. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B3373 concentration 10 ug/ml.


Anti-SOCS3 antibody IHC of human heart. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B3373 concentration 10 ug/ml.

Requested From: United States
Date Requested: 10/27/2016

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