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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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SNCA / Alpha‑Synuclein Antibody LS‑C39431
Antibody
Alpha-Synuclein antibody LS-C39431 is an unconjugated mouse monoclonal antibody to human Alpha-Synuclein (SNCA). Validated for IHC and WB.
Catalog
Size
Price
LS-C39431-100
100 µl
Unavailable

Popular SNCA / Alpha-Synuclein Products

Antibody
Species: Human
Applications: IHC, IHC - Paraffin, Western blot, Immunoprecipitation
Anti-SNCA / Alpha-Synuclein antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B2923 concentration 10 ug/ml.
Species: Human
Applications: IHC, IHC - Paraffin, Western blot, ELISA
Antibody
Species: Human, Mouse, Rat
Applications: Immunofluorescence, Western blot, ELISA
Antibody
Species: Human, Mouse, Rat
Applications: IHC, Western blot, ELISA
Antibody
Species: Human
Applications: ELISA

Product Description

Alpha-Synuclein antibody LS-C39431 is an unconjugated mouse monoclonal antibody to human Alpha-Synuclein (SNCA). Validated for IHC and WB.
About SNCA / Alpha-Synuclein
Alpha-synuclein is a member of the synuclein family, which also includes beta- and gamma-synuclein. Synucleins are abundantly expressed in the brain and alpha- and beta-synuclein inhibit phospholipase D2 selectively. SNCA may serve to integrate presynaptic signaling and membrane trafficking. Defects in SNCA have been implicated in the pathogenesis of Parkinson disease. SNCA peptides are a major component of amyloid plaques in the brains of patients with Alzheimer's disease. P37840 NM_000345 NP_000336.1

SNCA Antibody, Alpha-synuclein Antibody, PARK4 Antibody, PD1 Antibody, Synuclein alpha-140 Antibody, NACP Antibody, PARK1 Antibody


Specifications

Target
Human SNCA / Alpha-Synuclein
Host
Mouse
Reactivity
Human (tested or 100% immunogen sequence identity)
Clonality
IgG Monoclonal
Conjugations
Unconjugated
Purification
Tissue culture supernatant
Modifications
Unmodified
Applications
  • IHC
  • IHC - Frozen
  • Western blot
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Immunogen
Recombinant human full length alpha synuclein.
Specificity
Recognizes alpha Synuclein. By Western blot the antibody shows no reactivity with beta or gamma synuclein. This antibody was shown to stain Lewy bodies in frozen section of human brain with Parkinson's disease and glial inclusions in frozen section of human brain with Multiple System Atrophy. Species Reactivity: Human. Not recommended for use on rat.
Usage
Western blotting on recombinant alpha synuclein: 1:2000-1:4000. Immunohistochemistry (frozen sections): 1:250-1:500.
Presentation
No preservative.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Requested From: 
Date Requested: 6/23/2018

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