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Anti-SNCA / Alpha-Synuclein Antibody (clone 2A7) LS-C204583

Note: This antibody replaces LS-C143046

Ordering

Wt. Vol. Conc. Price
- 100 µl - $285
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)
206-374-1102
866-206-6909
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Most Popular SNCA / Alpha-Synuclein Antibodies

Anti-SNCA / Alpha-Synuclein Antibody (phospho-Ser129) LS-C153370
Rabbit Polyclonal to Human SNCA / Alpha-Synuclein
Human, Mouse, Rat
Immunofluorescence, Western blot, ELISA
Unconjugated
Anti-SNCA / Alpha-Synuclein Antibody (phospho-Ser87) LS-C153371
Rabbit Polyclonal to Human SNCA / Alpha-Synuclein
Human, Mouse, Rat
IHC, Western blot, ELISA
Unconjugated
Anti-SNCA / Alpha-Synuclein Antibody (HRP) LS-C212005
Rabbit Polyclonal (IgG) to Human SNCA / Alpha-Synuclein
Human
ELISA
HRP Conjugated

100% Guaranteed 100% Guaranteed
Mouse Monoclonal [clone 2A7] (IgG1) to Human SNCA / Alpha-Synuclein
Human
ICC, Immunofluorescence, Western blot
Unconjugated

Details

Human SNCA / Alpha-Synuclein
Mouse
Human (tested or 100% immunogen sequence identity)
IgG1 Monoclonal [2A7]
Unconjugated
Affinity purified
Unmodified

Applications

  • ICC (1:1000)
  • Immunofluorescence (1:1000)
  • Western blot

Specificity and Use

Try at dilutions of 1:1000 and higher for immunofluorescence.

Packaging

Liquid
+4°C or -20°C, Avoid repeated freezing and thawing.
For research use only.

About SNCA / Alpha-Synuclein

P37840 NM_000345 NP_000336.1

SNCA Antibody, Alpha-synuclein Antibody, PARK4 Antibody, PD1 Antibody, Synuclein alpha-140 Antibody, NACP Antibody, PARK1 Antibody

Alpha-synuclein is a member of the synuclein family, which also includes beta- and gamma-synuclein. Synucleins are abundantly expressed in the brain and alpha- and beta-synuclein inhibit phospholipase D2 selectively. SNCA may serve to integrate presynaptic signaling and membrane trafficking. Defects in SNCA have been implicated in the pathogenesis of Parkinson disease. SNCA peptides are a major component of amyloid plaques in the brains of patients with Alzheimer's disease.

Immunocytochemistry

Immunocytochemistry
Mixed neuron-glial cultures stained with SNCA / Alpha-Synuclein antibody, our monoclonal antibody to alpha-synuclein (red) and chicken polylclonal antibody to MAP2 CPCA-MAP2 (green). The alpha-synuclein antibody stains vesicular structures the perikarya and processes of the neurons in this image. Note that some of the neuronal perikarya contain much more alpha-synuclein than others. The blue channel shows the localization of DNA.

Western blot

Western blot
Blots of SNCA / Alpha-Synuclein antibody on recombinant alpha-synuclein (left lane) and crude extract of mouse brain (right lane, courtesy Rogan Tinsley, Howard Florey Institute, University of Melbourne).

Requested From: United States
Date Requested: 12/4/2016

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