Alpha-Synuclein antibody LS-C11497 is an unconjugated goat polyclonal antibody to human Alpha-Synuclein (SNCA). Validated for ELISA and IHC.
Human SNCA / Alpha-Synuclein
(tested or 100% immunogen sequence identity)
Rat (at least 90% immunogen sequence identity)
- IHC - Paraffin (1:300)
- ELISA (1:1000)
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Synthetic peptide corresponding to amino acids 116-131 of the C-terminus of a synuclein.
Recognizes human alpha-synuclein. The alpha-synuclein gene, located on chromosome 4, has been linked to early onset autosomal dominant Parkinson's disease. The protein is abundant in the nervous system, and is known to be the precursor of the non-beta amyloid component protein (NACP) of Alzheimer's disease. Alpha-synuclein has also been found to be associated with other neurodegenerative diseases such as multiple system atrophy and dementia with Lewy's bodies.
Immunohistology: This product does not require protein digestion pre-treatment of paraffin sections. This product does not require antigen retrieval using heat treatment prior to staining of paraffin sections.
Serum, 0.09% Sodium Azide
Store at 4°C or -20°C. Storage in frost-free freezers is not recommended. This product should be stored undiluted. Avoid freeze-thaw cycles as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
For research use only.
About SNCA / Alpha-Synuclein