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Anti-SNCA / Alpha-Synuclein Antibody (C-Terminus) LS-C11497

Ordering

Wt. Vol. Conc. Price
- 100 µl - $350
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)
206-374-1102
866-206-6909
Orders@LSBio.com
 

Most Popular SNCA / Alpha-Synuclein Antibodies

Anti-SNCA / Alpha-Synuclein Antibody (phospho-Ser129) LS-C153370
Rabbit Polyclonal to Human SNCA / Alpha-Synuclein
Human, Mouse, Rat
Immunofluorescence, Western blot, ELISA
Unconjugated
Anti-SNCA / Alpha-Synuclein Antibody (phospho-Ser87) LS-C153371
Rabbit Polyclonal to Human SNCA / Alpha-Synuclein
Human, Mouse, Rat
IHC, Western blot, ELISA
Unconjugated
Anti-SNCA / Alpha-Synuclein Antibody (HRP) LS-C212005
Rabbit Polyclonal (IgG) to Human SNCA / Alpha-Synuclein
Human
ELISA
HRP Conjugated

100% Guaranteed 100% Guaranteed
Goat Polyclonal (IgG) to Human SNCA / Alpha-Synuclein
Human
IHC - Paraffin, ELISA
Unconjugated

Details

Human SNCA / Alpha-Synuclein
Goat
Human (tested or 100% immunogen sequence identity)
IgG Polyclonal
Unconjugated
Antiserum
Unmodified

Applications

  • IHC - Paraffin (1:300)
  • ELISA (1:1000)

Specificity and Use

SNCA / Alpha-Synuclein antibody was raised against synthetic peptide corresponding to amino acids 116-131 of the C-terminus of a synuclein.
C-Terminus
Recognizes human alpha-synuclein. The alpha-synuclein gene, located on chromosome 4, has been linked to early onset autosomal dominant Parkinson's disease. The protein is abundant in the nervous system, and is known to be the precursor of the non-beta amyloid component protein (NACP) of Alzheimer's disease. Alpha-synuclein has also been found to be associated with other neurodegenerative diseases such as multiple system atrophy and dementia with Lewy's bodies.
Immunohistology: This product does not require protein digestion pre-treatment of paraffin sections. This product does not require antigen retrieval using heat treatment prior to staining of paraffin sections.

Packaging

Serum, 0.09% sodium azide.
For research use only.

About SNCA / Alpha-Synuclein

P37840 NM_000345 NP_000336.1

SNCA Antibody, Alpha-synuclein Antibody, PARK4 Antibody, PD1 Antibody, Synuclein alpha-140 Antibody, NACP Antibody, PARK1 Antibody

Alpha-synuclein is a member of the synuclein family, which also includes beta- and gamma-synuclein. Synucleins are abundantly expressed in the brain and alpha- and beta-synuclein inhibit phospholipase D2 selectively. SNCA may serve to integrate presynaptic signaling and membrane trafficking. Defects in SNCA have been implicated in the pathogenesis of Parkinson disease. SNCA peptides are a major component of amyloid plaques in the brains of patients with Alzheimer's disease.

Requested From: United States
Date Requested: 12/8/2016

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