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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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SNCA / Alpha‑Synuclein Antibody (aa134‑138) LS‑C205350
Alpha-Synuclein antibody LS-C205350 is an unconjugated rabbit polyclonal antibody to Alpha-Synuclein (SNCA) from human, mouse and rat. Validated for IF and WB.
Catalog
Size
Price
LS-C205350-50
50 µg (1 mg/ml)
Unavailable

Popular SNCA / Alpha-Synuclein Products

Antibody
Species: Human
Applications: IHC, IHC - Paraffin, Western blot, Immunoprecipitation
Anti-SNCA / Alpha-Synuclein antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B2923 concentration 10 ug/ml.
Species: Human
Applications: IHC, IHC - Paraffin, Western blot, ELISA
Antibody
Species: Human, Mouse, Rat
Applications: Immunofluorescence, Western blot, ELISA
Antibody
Species: Human, Mouse, Rat
Applications: IHC, Western blot, ELISA
Antibody
Species: Human
Applications: ELISA

Product Description

Alpha-Synuclein antibody LS-C205350 is an unconjugated rabbit polyclonal antibody to Alpha-Synuclein (SNCA) from human, mouse and rat. Validated for IF and WB.
About SNCA / Alpha-Synuclein
Alpha-synuclein is a member of the synuclein family, which also includes beta- and gamma-synuclein. Synucleins are abundantly expressed in the brain and alpha- and beta-synuclein inhibit phospholipase D2 selectively. SNCA may serve to integrate presynaptic signaling and membrane trafficking. Defects in SNCA have been implicated in the pathogenesis of Parkinson disease. SNCA peptides are a major component of amyloid plaques in the brains of patients with Alzheimer's disease. P37840 NM_000345 NP_000336.1

SNCA Antibody, Alpha-synuclein Antibody, PARK4 Antibody, PD1 Antibody, Synuclein alpha-140 Antibody, NACP Antibody, PARK1 Antibody


Specifications

Target
Human SNCA / Alpha-Synuclein
Host
Rabbit
Reactivity
Human, Mouse, Rat (tested or 100% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated
Purification
Immunoaffinity purified
Modifications
Unmodified
Applications
  • Immunofluorescence (1:100 - 1:200)
  • Western blot (1:500 - 1:1000)
Immunogen
Peptide sequence around amino acids 134-138 (Q-D-Y-E-P) of Human alpha-Synuclein.
Epitope
aa134-138
Specificity
The antibody detects endogenous levels of total a-Synuclein protein.
Presentation
PBS (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Images


Immunofluorescence

Immunofluorescence of methanol-fixed HeLa cells using a-Synuclein (aa134-138) antibody.
Immunofluorescence of methanol-fixed HeLa cells using a-Synuclein (aa134-138) antibody.

Western blot

Western blot of extracts from HeLa and 3T3 cells using a-Synuclein (aa134-138) antibody.
Western blot of extracts from HeLa and 3T3 cells using a-Synuclein (aa134-138) antibody.

Immunofluorescence

Immunofluorescence of methanol-fixed HeLa cells using a-Synuclein (aa134-138) antibody.
Immunofluorescence of methanol-fixed HeLa cells using a-Synuclein (aa134-138) antibody.

Western blot

Western blot of extracts from HeLa and 3T3 cells using a-Synuclein (aa134-138) antibody.
Western blot of extracts from HeLa and 3T3 cells using a-Synuclein (aa134-138) antibody.

Immunofluorescence

Immunofluorescence of methanol-fixed HeLa cells using a-Synuclein (aa134-138) antibody.
Immunofluorescence of methanol-fixed HeLa cells using a-Synuclein (aa134-138) antibody.

Western blot

Western blot of extracts from HeLa and 3T3 cells using a-Synuclein (aa134-138) antibody.
Western blot of extracts from HeLa and 3T3 cells using a-Synuclein (aa134-138) antibody.

Immunofluorescence

Immunofluorescence of methanol-fixed HeLa cells using a-Synuclein (aa134-138) antibody.
Immunofluorescence of methanol-fixed HeLa cells using a-Synuclein (aa134-138) antibody.

Western blot

Western blot of extracts from HeLa and 3T3 cells using a-Synuclein (aa134-138) antibody.
Western blot of extracts from HeLa and 3T3 cells using a-Synuclein (aa134-138) antibody.


Requested From: 
Date Requested: 6/20/2018

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