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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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SMYD2 Antibody (Leu148) LS‑C178248
SMYD2 antibody LS-C178248 is an unconjugated rabbit polyclonal antibody to SMYD2 from human, mouse and rat. Validated for WB.
Catalog
Size
Price
LS-C178248-100
100 µl
Unavailable

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Product Description

SMYD2 antibody LS-C178248 is an unconjugated rabbit polyclonal antibody to SMYD2 from human, mouse and rat. Validated for WB.
About SMYD2
Protein-lysine N-methyltransferase that methylates both histones and non-histone proteins, including p53/TP53 and RB1. Specifically methylates histone H3 'Lys-4' (H3K4me) and dimethylates histone H3 'Lys-36' (H3K36me2). Shows even higher methyltransferase activity on p53/TP53. Monomethylates 'Lys-370' of p53/TP53, leading to decreased DNA-binding activity and subsequent transcriptional regulation activity of p53/TP53. Monomethylates RB1 at 'Lys-860'. Q9NRG4 NM_020197 NP_064582.2

SMYD2 Antibody, HSKM-B Antibody, KMT3C Antibody, Lysine N-methyltransferase 3C Antibody, ZMYND14 Antibody


Specifications

Target
Human SMYD2
Host
Rabbit
Reactivity
Human, Mouse, Rat (tested or 100% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated
Purification
Immunoaffinity purified
Modifications
Unmodified
Applications
  • Western blot
Immunogen
SMYD2 antibody was raised against synthetic peptide around Leu148 of human SMYD2
Epitope
Leu148
Specificity
Human SMYD2
Presentation
PBS, pH 7.2, 0.05% sodium azide
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Images


Western blot

Western blot of SMYD2 (L148) pAb in extracts from HT29 cells.
Western blot of SMYD2 (L148) pAb in extracts from HT29 cells.

Western blot

Western blot of SMYD2 (L148) pAb in extracts from HT29 cells.
Western blot of SMYD2 (L148) pAb in extracts from HT29 cells.

Western blot

Western blot of SMYD2 (L148) pAb in extracts from HT29 cells.
Western blot of SMYD2 (L148) pAb in extracts from HT29 cells.

Western blot

Western blot of SMYD2 (L148) pAb in extracts from HT29 cells.
Western blot of SMYD2 (L148) pAb in extracts from HT29 cells.


Requested From: 
Date Requested: 6/21/2018

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