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Anti-SMYD2 Antibody (Leu148) LS-C178248

Ordering

Wt. Vol. Conc. Price
- 100 µl - Unavailable

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100% Guaranteed 100% Guaranteed
Rabbit Polyclonal to Human SMYD2
Human, Mouse, Rat
Western blot
Unconjugated

Details

Human SMYD2
Rabbit
Human, Mouse, Rat (tested or 100% immunogen sequence identity)
Polyclonal
Unconjugated
Immunoaffinity purified
Unmodified

Applications

Western blot

Specificity and Use

SMYD2 antibody was raised against synthetic peptide around Leu148 of human SMYD2
Leu148
Human SMYD2

Packaging

PBS, pH 7.2, 0.05% sodium azide
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only.

About SMYD2

Q9NRG4 NM_020197 NP_064582.2

SMYD2 Antibody, HSKM-B Antibody, KMT3C Antibody, Lysine N-methyltransferase 3C Antibody, ZMYND14 Antibody

Protein-lysine N-methyltransferase that methylates both histones and non-histone proteins, including p53/TP53 and RB1. Specifically methylates histone H3 'Lys-4' (H3K4me) and dimethylates histone H3 'Lys-36' (H3K36me2). Shows even higher methyltransferase activity on p53/TP53. Monomethylates 'Lys-370' of p53/TP53, leading to decreased DNA-binding activity and subsequent transcriptional regulation activity of p53/TP53. Monomethylates RB1 at 'Lys-860'.

Western blot

Western blot
Western blot of SMYD2 (L148) pAb in extracts from HT29 cells.

Requested From: 
Date Requested: 4/28/2017

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