Products

Antibodies
All Antibodies
Primary Antibodies
Secondary Antibodies
IHC-plus Antibodies
Isotype Control Antibodies

ELISA and Assay Kits
All Kits
Assay Kits
Traditional ELISA Kits
Cell-Based ELISA Kits
DNA-Binding ELISA Kits
Phospho-Specific ELISA Kits
ELISA Development Kits
Chemiluminescent CLIA Kits

Proteins
All Proteins
Recombinant Proteins
Native Proteins
Over-expression Lysates
Cell and Tissue Lysates
Bio-active Proteins
Animal-free Proteins
Synthetic Peptides

Biochemicals
All Biochemicals

Immunohistochemistry
Comprehensive IHC Reports
Custom IHC Services
TCR Screening Services
IHC-plus Antibodies

Services

Immunohistochemistry Services

Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

TCR Screening Services

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

Have a question? CustomerSupport@LSBio.com

Resources

Purchasing
Product Ordering Terms and Conditions
Holiday Schedule
About the LSBio Guarantee
About Our Rewards Program

Reference Material
About LSBio (LifeSpan BioSciences Inc.)
About Our 2-million Specimen Tissue Bank
About Our IHC Validation Process
About Our IHC-plus™ Immunohistochemistry Protocol
Protocols

Secure Logins
Login to Our Secure ShareFile Site
Login to Our IHC Database

Distributors

LSBio
2401 Fourth Avenue Suite 900
Seattle WA 98121

Phone:	866-819-4732 (Toll Free North America) 206-374-1102 (International)

Fax:	866-206-6909 (Toll Free North America) 206-577-4565 (International)

How to Buy - Details about how to buy our products.

Orders@LSBio.com - To submit a new order.

Customer.Support@LSBio.com - To submit questions about existing orders, pricing, availability, bulk quotes, proforma invoice requests, or other billing issues.

Technical.Support@LSBio.com - To request technical information requests about an LSBio product or its application.

Sales@LSBio.com - To request information about fee-for-service contract IHC studies, IHC reports, distribution agreements, or general business development.

Worldwide Distributors List - To find your local distributor if you're not within the United States.

Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions,
rewards, and special promotions.

Login Name:
Password:

Forgot password?

Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions,
rewards, and special promotions.

Login Name*:
Email*:
Password*:
Confirm Password*:
Name:
Organization:
Role:

Fields marked with a * are required.

Wish List

View Cart

Anti-SMYD2 Antibody (Leu148) LS-C178248

Catalog	Size	Price
LS-C178248-100	100 µl	Unavailable

Related Products

20 SMYD2 Antibodies

Most Popular SMYD2 Antibodies

Anti-SMYD2 Antibody (C-Terminus) LS-C111286

Antibody:	Rabbit Polyclonal to Human SMYD2
Reactivity:	Human, Monkey, Mouse, Rat, Bat, Bovine, Dog, Horse, Pig, Rabbit, Zebrafish
Application:	Western blot
Format:	Unconjugated

Anti-SMYD2 Antibody (aa99-148) LS-C200005

Antibody:	Rabbit Polyclonal (IgG) to Human SMYD2
Reactivity:	Human, Mouse, Rat
Application:	Western blot, ELISA
Format:	Unconjugated

Anti-SMYD2 Antibody LS-C334744

Antibody:	Rabbit Polyclonal (IgG) to Human SMYD2
Reactivity:	Human, Mouse, Rat
Application:	IHC, Immunofluorescence, Western blot
Format:	Unconjugated

Anti-SMYD2 Antibody (Internal) LS-C386113

Antibody:	Rabbit Polyclonal (IgG) to Human SMYD2
Reactivity:	Human, Mouse, Rat
Application:	Western blot, ELISA
Format:	Unconjugated

Anti-SMYD2 Antibody LS-C394089

Antibody:	Mouse Monoclonal to Human SMYD2
Reactivity:	Human, Mouse
Application:	Western blot
Format:	Unconjugated

Antibody:	Rabbit Polyclonal to Human SMYD2
Reactivity:	Human, Mouse, Rat
Application:	Western blot
Format:	Unconjugated

Details

Target:	Human SMYD2
Host:	Rabbit
Reactivity:	Human, Mouse, Rat (tested or 100% immunogen sequence identity)
Clonality:	Polyclonal
Conjugations:	Unconjugated
Purification:	Immunoaffinity purified
Modifications:	Unmodified

Applications

Approved:

Western blot

Specificity and Use

Immunogen:	SMYD2 antibody was raised against synthetic peptide around Leu148 of human SMYD2
Epitope:	Leu148
Specificity:	Human SMYD2

Packaging

Presentation:	PBS, pH 7.2, 0.05% sodium azide
Storage:	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Restrictions:	For research use only.

About SMYD2

Uniprot: Q9NRG4 NCBI: NM_020197 NP_064582.2

Synonyms: SMYD2 Antibody, HSKM-B Antibody, KMT3C Antibody, Lysine N-methyltransferase 3C Antibody, ZMYND14 Antibody

Description: Protein-lysine N-methyltransferase that methylates both histones and non-histone proteins, including p53/TP53 and RB1. Specifically methylates histone H3 'Lys-4' (H3K4me) and dimethylates histone H3 'Lys-36' (H3K36me2). Shows even higher methyltransferase activity on p53/TP53. Monomethylates 'Lys-370' of p53/TP53, leading to decreased DNA-binding activity and subsequent transcriptional regulation activity of p53/TP53. Monomethylates RB1 at 'Lys-860'.

(More About SMYD2)

Print This Page Email

Technical Help Review

Review This Product

Western blot

Western blot of SMYD2 (L148) pAb in extracts from HT29 cells.

Requested From:
Date Requested: 10/22/2017

Get Social With Us!

Catalog Number