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Anti-SMURF2 Antibody (aa6-36) LS-C98005

Ordering

Wt. Vol. Conc. Price
- 400 µl - $305
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)
206-374-1102
866-206-6909
Orders@LSBio.com
 

Most Popular SMURF2 Antibodies

Anti-SMURF2 Antibody (aa161-174) LS-C10240
Rabbit Polyclonal (IgG) to Human SMURF2
Human, Monkey, Mouse, Rat, Bat, Bovine, Dog, Hamster, Horse, Rabbit, Chicken, Xenopus, Zebrafish
Western blot
Unconjugated
Anti-SMURF2 Antibody (aa2-15) LS-C132145
Goat Polyclonal (IgG) to Human SMURF2
Human, Mouse, Rabbit
Western blot
Unconjugated
Anti-SMURF2 Antibody (N-Terminus) IHC-plus™ LS-B12061
Rabbit Polyclonal to Human SMURF2
Human, Mouse, Rat
IHC - Paraffin, Immunofluorescence, Western blot, ELISA
Unconjugated
Immunohistochemistry Image

100% Guaranteed 100% Guaranteed Publications Publications (1)
Rabbit Polyclonal to Human SMURF2
Human, Mouse
IHC - Paraffin, Western blot
Unconjugated

Details

Human SMURF2
Rabbit
Human, Mouse (tested or 100% immunogen sequence identity)
Zebrafish (at least 90% immunogen sequence identity)
Polyclonal
Unconjugated
Ammonium sulfate precipitation
Unmodified

Applications

  • IHC - Paraffin (1:50 - 1:100)
  • Western blot (1:1000)

Specificity and Use

LS-E6854 - Lyophilized - 100 µg - $145.00
aa6-36
This SMURF2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 6-36 amino acids from the N-terminal region of human SMURF2.

Packaging

PBS, 0.09% sodium azide
Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
For research use only.

Publications (1)

1
Ubiquitination of the GTPase Rap1B by the ubiquitin ligase Smurf2 is required for the establishment of neuronal polarity. Schwamborn JC, Mller M, Becker AH, Pschel AW. The EMBO journal. 2007 26:1410-22. [PubMed:17318188] [PMC:PMC1817628]

About SMURF2

Q9HAU4 NM_022739 NP_073576.1

SMURF2 Antibody, E3 ubiquitin ligase SMURF2 Antibody, HSMURF2 Antibody

E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Interacts with SMAD1 and SMAD7 in order to trigger their ubiquitination and proteasome-dependent degradation. In addition, interaction with SMAD7 activates autocatalytic degradation, which is prevented by interaction with SCYE1.

Immunohistochemistry

Immunohistochemistry
Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.

Western blot

Western blot
The anti-SMURF2 antibody is used in Western blot to detect SMURF2 in mouse brain tissue lysate.

Requested From: United States
Date Requested: 2/26/2017

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