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SMURF1
SMAD specific E3 ubiquitin protein ligase 1
E3 ubiquitin-protein ligase that acts as a negative regulator of BMP signaling pathway. Mediates ubiquitination and degradation of SMAD1 and SMAD5, 2 receptor-regulated SMADs specific for the BMP pathway. Promotes ubiquitination and subsequent proteasomal degradation of TRAF family members and RHOA.
| Gene Name: | SMAD specific E3 ubiquitin protein ligase 1 |
| Synonyms: | SMURF1, E3 ubiquitin ligase SMURF1, KIAA1625, HSMURF1 |
| Target Sequences: | NP_851994.1 Q9HCE7 |
Publications (1)
1
Ubiquitination of the GTPase Rap1B by the ubiquitin ligase Smurf2 is required for the establishment of neuronal polarity. Schwamborn JC, Mller M, Becker AH, Pschel AW. The EMBO journal. 2007 26:1410-22.
[PubMed:17318188]
[PMC:PMC1817628]
Related Antibodies: LS-B3450.
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SMURF1 Rabbit anti-Human Polyclonal (aa66-96) Antibody
Mouse, Human
IHC, IHC-P, WB
Unconjugated
200 µl/$440
SMURF1 Mouse anti-Human Monoclonal (1D7) Antibody
Mouse, Human
ELISA, IF, IHC, IHC-P, IP, WB
Unconjugated
50 µg/$440
SMURF1 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
ELISA, IF, IHC
Unconjugated
50 µg/$294; 100 µg/$360
SMURF1 Rabbit anti-Human Polyclonal (FITC) Antibody
Human
ELISA
FITC Conjugated
50 µg/$294; 100 µg/$360
SMURF1 Rabbit anti-Human Polyclonal (aa711-740) Antibody
Human
IHC, IHC-P, WB
Unconjugated
400 µl/$393
SMURF1 Rabbit anti-Human Polyclonal (aa711-740) Antibody
Human
ELISA, IHC, WB
Unconjugated
200 µl/$734
SMURF1 Rabbit anti-Human Polyclonal (aa711-740) (Biotin) Antibody
Human
ELISA, IHC, WB
Biotin Conjugated
200 µl/$952
SMURF1 Rabbit anti-Human Polyclonal (aa711-740) (FITC) Antibody
Human
ELISA, IHC, WB
FITC Conjugated
200 µl/$952
SMURF1 Rabbit anti-Human Polyclonal (aa711-740) (APC) Antibody
Human
ELISA, IHC, WB
APC Conjugated
200 µl/$952
SMURF1 Rabbit anti-Human Polyclonal (aa711-740) (PE) Antibody
Human
ELISA, IHC, WB
PE Conjugated
200 µl/$952
SMURF1 Rabbit anti-Human Polyclonal (aa711-740) (Azide-free) (HRP) Antibody
Human
ELISA, IHC, WB
HRP Conjugated, Azide-free
200 µl/$952
SMURF1 Rabbit anti-Human Polyclonal (aa66-96) Antibody
Mouse, Human
ELISA, IHC, WB
Unconjugated
200 µl/$734
SMURF1 Rabbit anti-Human Polyclonal (aa66-96) (Biotin) Antibody
Mouse, Human
ELISA, IHC, WB
Biotin Conjugated
200 µl/$952
SMURF1 Rabbit anti-Human Polyclonal (aa66-96) (FITC) Antibody
Mouse, Human
ELISA, IHC, WB
FITC Conjugated
200 µl/$952
SMURF1 Rabbit anti-Human Polyclonal (aa66-96) (PE) Antibody
Mouse, Human
ELISA, IHC, WB
PE Conjugated
200 µl/$952
SMURF1 Rabbit anti-Human Polyclonal (aa66-96) (APC) Antibody
Mouse, Human
ELISA, IHC, WB
APC Conjugated
200 µl/$952
SMURF1 Rabbit anti-Human Polyclonal (aa66-96) (Azide-free) (HRP) Antibody
Mouse, Human
ELISA, IHC, WB
HRP Conjugated, Azide-free
200 µl/$952
SMURF1 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, WB
Unconjugated
100 µg/$341
SMURF1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
0.1 mg/$460
SMURF1 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
100 µl/$688
SMURF1 Rabbit anti-Human Polyclonal (aa352-381) Antibody
Mouse, Human
ELISA, WB
Unconjugated
200 µl/$734
SMURF1 Rabbit anti-Human Polyclonal (aa352-381) (Biotin) Antibody
Mouse, Human
ELISA, WB
Biotin Conjugated
200 µl/$952
SMURF1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, WB
Unconjugated
0.1 mg/$394
SMURF1 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
SMURF1 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
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